Phlorizin
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- $12 - $875
- Product name: Phlorizin
- CAS: 60-81-1
- MF: C21H24O10
- MW: 436.41
- EINECS:200-487-1
- MDL Number:MFCD00006591
- Synonyms:1-propanone,1-(2-(beta-d-glucopyranosyloxy)-4,6-dihydroxyphenyl)-3-(4-hydroxyp ;phlorhizin ;phloridzine ;phlorizine ;phlorizoside ;1-Propanone, 1-[2-(β-D-glucopyranosyloxy)-;4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-;Floridzin
52 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- JR MediChem
- Labseeker
- Matrix Scientific
- Medical Isotopes, Inc.
- Oakwood
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 10mM(in 1mL DMSO)
- 5MG
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- 2g
- 2.5g
- 5G
- 10g
- 20g
- 25g
- 100g
- 250G
- ManufacturerAdipogen Life Sciences
- Product numberCDX-P0263-G001
- Product descriptionPhloridzin ≥98%(HPLC)
- Packaging1g
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-57943
- Product descriptionPhloridzin 98%
- Packaging20g
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberQ438
- Product descriptionPhloridzin
- Packaging25g
- Price$114
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberQ438
- Product descriptionPhloridzin
- Packaging100g
- Price$343
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCCH0011618
- Product description1-[2,4-DIHYDROXY-6-[(2S,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]OXYPHENYL]-3-(4-HYDROXYPHENYL)PROPAN-1-ONE 95.00%
- Packaging5MG
- Price$499.11
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN1876
- Product descriptionPhloridzin
- Packaging1g
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN1876
- Product descriptionPhloridzin
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS026279
- Product descriptionPhloridzin
- Packaging25g
- Price$97
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS026279
- Product descriptionPhloridzin
- Packaging10g
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN97038
- Product descriptionPhlorizin ≥98%
- Packaging20mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS026279
- Product descriptionPhloridzin
- Packaging1g
- Price$12
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3283
- Product descriptionPhlorizin
- Packaging25mg
- Price$29
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3283
- Product descriptionPhlorizin
- Packaging100mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3283
- Product descriptionPhlorizin
- Packaging250mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3283
- Product descriptionPhlorizin
- Packaging1g
- Price$89
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb259436
- Product descriptionPhlorizin 99%
- Packaging100mg
- Price$306
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | CDX-P0263-G001 | Phloridzin ≥98%(HPLC) | 1g | $59 | 2021-12-16 | Buy |
| AHH | MT-57943 | Phloridzin 98% | 20g | $350 | 2021-12-16 | Buy |
| AK Scientific | Q438 | Phloridzin | 25g | $114 | 2021-12-16 | Buy |
| AK Scientific | Q438 | Phloridzin | 100g | $343 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CCH0011618 | 1-[2,4-DIHYDROXY-6-[(2S,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]OXYPHENYL]-3-(4-HYDROXYPHENYL)PROPAN-1-ONE 95.00% | 5MG | $499.11 | 2021-12-16 | Buy |
| ApexBio Technology | N1876 | Phloridzin | 1g | $50 | 2021-12-16 | Buy |
| ApexBio Technology | N1876 | Phloridzin | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| Arctom | AS026279 | Phloridzin | 25g | $97 | 2021-12-16 | Buy |
| Arctom | AS026279 | Phloridzin | 10g | $45 | 2021-12-16 | Buy |
| Arctom | CFN97038 | Phlorizin ≥98% | 20mg | $30 | 2021-12-16 | Buy |
| Arctom | AS026279 | Phloridzin | 1g | $12 | 2021-12-16 | Buy |
| AvaChem | 3283 | Phlorizin | 25mg | $29 | 2021-12-16 | Buy |
| AvaChem | 3283 | Phlorizin | 100mg | $39 | 2021-12-16 | Buy |
| AvaChem | 3283 | Phlorizin | 250mg | $49 | 2021-12-16 | Buy |
| AvaChem | 3283 | Phlorizin | 1g | $89 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb259436 | Phlorizin 99% | 100mg | $306 | 2021-12-16 | Buy |
Properties
Melting point :113-114 °C(lit.)
Boiling point :468.89°C (rough estimate)
Density :1.3178 (rough estimate)
refractive index :-54 ° (C=3.2, 95% EtOH)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :7.15±0.40(Predicted)
color :Light Yellow to Tan
Merck :14,7327
InChIKey :IOUVKUPGCMBWBT-LKLLPNDVNA-N
SMILES :C(C1C(=CC(O)=CC=1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O)(=O)CCC1C=CC(O)=CC=1 |&1:9,10,11,13,15,r|
LogP :0.452 (est)
CAS DataBase Reference :60-81-1(CAS DataBase Reference)
EPA Substance Registry System :Phlorizin (60-81-1)
Boiling point :468.89°C (rough estimate)
Density :1.3178 (rough estimate)
refractive index :-54 ° (C=3.2, 95% EtOH)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :7.15±0.40(Predicted)
color :Light Yellow to Tan
Merck :14,7327
InChIKey :IOUVKUPGCMBWBT-LKLLPNDVNA-N
SMILES :C(C1C(=CC(O)=CC=1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O)(=O)CCC1C=CC(O)=CC=1 |&1:9,10,11,13,15,r|
LogP :0.452 (est)
CAS DataBase Reference :60-81-1(CAS DataBase Reference)
EPA Substance Registry System :Phlorizin (60-81-1)
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Sodium-glucose cotransporter 1 (SGLT1) is a high affinity, low capacity transporter abundant in the small intestine, with some expression in the kidney as well. SGLT2 is a low affinity, high capacity transporter in the kidney that accounts for approximately 90% of glucose reabsorption into the blood stream. Selective inhibition of SGLT2 is a potential strategy for reducing plasma glucose levels as a treatment for diabetes. Phlorizin is a natural product, first isolated from the bark of apple trees, that reduces plasma glucose levels by blocking renal and intestinal glucose absorption through inhibition of SGLT1 and SGLT2. It competitively inhibits the initial rate of a-methyl-D-glucopyranoside (a-MDG) uptake in human COS-1 cells expressing hSGLT1 and hSGLT2 with IC50 values of 400 and 65 nM, respectively. In HEK293T cells expressing human SGLT1 and SGLT2, phlorizin exhibits Ki values of 140 and 11 nM, respectively, at 37°C.Related product price
- 1,3-Dihydroxyacetone
$9-2868.16 - Hydroxyacetone
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$5-3326.4
Suppliers and manufacturers
Shaanxi LonierHerb Bio Technology Co Ltd
Hangzhou FandaChem Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Shanghai Zheyan Biotech Co., Ltd.
