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ChemicalBook >> CAS DataBase List >> Osthole

Osthole

Osthole price.
  • $7 - $2021.25
  • Product name: Osthole
  • CAS: 484-12-8
  • MF: C15H16O3
  • MW: 244.29
  • EINECS:1532714-185-1
  • MDL Number:MFCD00076049
  • Synonyms:Cnidiumfruitextract;Osthol/Osthole;Cnidium;OSTHOLE(P);Epiandrosterone, 99%, HPLC;Cnidiumlactone，Osthol;7-Methoxy-8-prenyl-2H-1-benzopyran-2-one;7-Methoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one
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  • Adipogen Life Sciences
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  • Cayman Chemical
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Package
  • 25MG
  • 10mM(in 1mL DMSO)
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-O0097-M010
  • Product descriptionOsthole ≥95%(HPLC)
  • Packaging10mg
  • Price$71
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10077
  • Product descriptionOsthol
  • Packaging5mg
  • Price$34.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberW1256
  • Product descriptionOsthol
  • Packaging10g
  • Price$68
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ10077
  • Product descriptionOsthol
  • Packaging100mg
  • Price$298.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA141553
  • Product description7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one 98+%
  • Packaging250mg
  • Price$7
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA141553
  • Product description7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one 98+%
  • Packaging1g
  • Price$18
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA141553
  • Product description7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one 98+%
  • Packaging5g
  • Price$57
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA141553
  • Product description7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one 98+%
  • Packaging10g
  • Price$107
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA141553
  • Product description7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one 98+%
  • Packaging25g
  • Price$206
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0005322
  • Product description7-METHOXY-8-(3-METHYL-BUT-2-ENYL)-CHROMEN-2-ONE 95.00%
  • Packaging25MG
  • Price$226.8
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0005322
  • Product description7-METHOXY-8-(3-METHYL-BUT-2-ENYL)-CHROMEN-2-ONE 95.00%
  • Packaging1G
  • Price$831.6
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0005322
  • Product description7-METHOXY-8-(3-METHYL-BUT-2-ENYL)-CHROMEN-2-ONE 95.00%
  • Packaging5G
  • Price$1409.1
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0005322
  • Product description7-METHOXY-8-(3-METHYL-BUT-2-ENYL)-CHROMEN-2-ONE 95.00%
  • Packaging10G
  • Price$2021.25
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberN1825
  • Product descriptionOsthole
  • Packaging500mg
  • Price$50
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberN1825
  • Product descriptionOsthole
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS032908
  • Product description7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one ≥98%
  • Packaging250mg
  • Price$7
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-O0097-M010 Osthole ≥95%(HPLC) 10mg $71 2021-12-16 Buy
AK Scientific J10077 Osthol 5mg $34.6 2021-12-16 Buy
AK Scientific W1256 Osthol 10g $68 2021-12-16 Buy
AK Scientific J10077 Osthol 100mg $298.6 2021-12-16 Buy
Ambeed A141553 7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one 98+% 250mg $7 2021-12-16 Buy
Ambeed A141553 7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one 98+% 1g $18 2021-12-16 Buy
Ambeed A141553 7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one 98+% 5g $57 2021-12-16 Buy
Ambeed A141553 7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one 98+% 10g $107 2021-12-16 Buy
Ambeed A141553 7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one 98+% 25g $206 2021-12-16 Buy
American Custom Chemicals Corporation PXT0005322 7-METHOXY-8-(3-METHYL-BUT-2-ENYL)-CHROMEN-2-ONE 95.00% 25MG $226.8 2021-12-16 Buy
American Custom Chemicals Corporation PXT0005322 7-METHOXY-8-(3-METHYL-BUT-2-ENYL)-CHROMEN-2-ONE 95.00% 1G $831.6 2021-12-16 Buy
American Custom Chemicals Corporation PXT0005322 7-METHOXY-8-(3-METHYL-BUT-2-ENYL)-CHROMEN-2-ONE 95.00% 5G $1409.1 2021-12-16 Buy
American Custom Chemicals Corporation PXT0005322 7-METHOXY-8-(3-METHYL-BUT-2-ENYL)-CHROMEN-2-ONE 95.00% 10G $2021.25 2021-12-16 Buy
ApexBio Technology N1825 Osthole 500mg $50 2021-12-16 Buy
ApexBio Technology N1825 Osthole 10mM(in 1mL DMSO) $50 2021-12-16 Buy
Arctom AS032908 7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one ≥98% 250mg $7 2021-12-16 Buy

Properties

Melting point :83-84°C
Boiling point :347.2°C (rough estimate)
Density :1.1263 (rough estimate)
refractive index :1.5570 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :methanol: soluble10mg/mL, clear, colorless
form :powder
color :white
Odor :at 100.00 %. dry musty herbal
Odor Type :dry
Water Solubility :12mg/L(25 ºC)
λmax :322nm(MeOH)(lit.)
Merck :14,6895
InChIKey :MBRLOUHOWLUMFF-UHFFFAOYSA-N
LogP :3.686 (est)
CAS DataBase Reference :484-12-8(CAS DataBase Reference)
NIST Chemistry Reference :Osthole(484-12-8)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

Osthole is a natural coumarin that was first isolated from several medicinal plants, including C. monnieri and A. pubescens. It is reported to induce a nonspecific elevation of cAMP and cGMP levels through its ability to inhibit phosphodiesterases, which leads to a modulation of calcium channel signaling and vasorelaxant effects. Osthole exhibits immunomodulatory, antioxidative, and anti-inflammatory properties, by regulating the expression of TNF-α, NF-κB, TGF-β, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. It also demonstrates antifibrotic effects in both hepatic and myocardial tissues and has been suggested to be a natural activator of defective delta F508-cystic fibrosis transmembrane conductance regulator chloride channel gating.

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