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ChemicalBook >> CAS DataBase List >> Nedaplatin

Nedaplatin

Nedaplatin price.
  • $15 - $1500
  • Product name: Nedaplatin
  • CAS: 95734-82-0
  • MF: C2H6N2O3Pt
  • MW: 301.17
  • EINECS:
  • MDL Number:MFCD00866374
  • Synonyms:(glycolato-o,o')diammineplatinum(ii);cis-diammine(glycolato)platinum(ii);NEDAPLATIN;254-s ;o(sup2))-diammine(hydroxyacetato(2-)-o(sup1(sp-4-3)-platinu ;Nedaplait;o(sup 2))- diammine(hydroxyacetato(2-)-o(sup 1 (sp-4-3)-platinu (glycolato-o,o')diammineplatinum(ii) 254-s cis-diammine(glycolato)platinum(ii) nedaplatin nsc 375101d;2,2-diaMino-1,3-dioxa-2-platinacyclopentan-4-one
28 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 5mg
  • 10MG
  • 25MG
  • 50MG
  • 100mg
  • 0.1g
  • 250mg
  • 1g
  • ManufacturerAHH
  • Product numberMT-56816
  • Product descriptionNedaplatin 98%
  • Packaging0.1g
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberM754
  • Product descriptionNedaplatin
  • Packaging100mg
  • Price$800
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003521
  • Product descriptionNEDAPLATIN 95.00%
  • Packaging10MG
  • Price$702.43
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003521
  • Product descriptionNEDAPLATIN 95.00%
  • Packaging25MG
  • Price$896.58
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003521
  • Product descriptionNEDAPLATIN 95.00%
  • Packaging50MG
  • Price$1171.88
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1986
  • Product descriptionNedaplatin
  • Packaging10mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS425197
  • Product description(SP-4-3)-Diammine[2-(hydroxy-κO)acetato(2-)-κO]platinum ≥98%
  • Packaging5mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS425197
  • Product description(SP-4-3)-Diammine[2-(hydroxy-κO)acetato(2-)-κO]platinum ≥98%
  • Packaging10mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS425197
  • Product description(SP-4-3)-Diammine[2-(hydroxy-κO)acetato(2-)-κO]platinum ≥98%
  • Packaging50mg
  • Price$33
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS425197
  • Product description(SP-4-3)-Diammine[2-(hydroxy-κO)acetato(2-)-κO]platinum ≥98%
  • Packaging100mg
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS425197
  • Product description(SP-4-3)-Diammine[2-(hydroxy-κO)acetato(2-)-κO]platinum ≥98%
  • Packaging250mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS425197
  • Product description(SP-4-3)-Diammine[2-(hydroxy-κO)acetato(2-)-κO]platinum ≥98%
  • Packaging1g
  • Price$217
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29001
  • Product descriptionNedaplatin
  • Packaging25mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29001
  • Product descriptionNedaplatin
  • Packaging50mg
  • Price$152
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29001
  • Product descriptionNedaplatin
  • Packaging100mg
  • Price$287
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29001
  • Product descriptionNedaplatin
  • Packaging250mg
  • Price$671
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-56816 Nedaplatin 98% 0.1g $400 2021-12-16 Buy
AK Scientific M754 Nedaplatin 100mg $800 2021-12-16 Buy
American Custom Chemicals Corporation API0003521 NEDAPLATIN 95.00% 10MG $702.43 2021-12-16 Buy
American Custom Chemicals Corporation API0003521 NEDAPLATIN 95.00% 25MG $896.58 2021-12-16 Buy
American Custom Chemicals Corporation API0003521 NEDAPLATIN 95.00% 50MG $1171.88 2021-12-16 Buy
ApexBio Technology B1986 Nedaplatin 10mg $77 2021-12-16 Buy
Arctom AS425197 (SP-4-3)-Diammine[2-(hydroxy-κO)acetato(2-)-κO]platinum ≥98% 5mg $15 2021-12-16 Buy
Arctom AS425197 (SP-4-3)-Diammine[2-(hydroxy-κO)acetato(2-)-κO]platinum ≥98% 10mg $20 2021-12-16 Buy
Arctom AS425197 (SP-4-3)-Diammine[2-(hydroxy-κO)acetato(2-)-κO]platinum ≥98% 50mg $33 2021-12-16 Buy
Arctom AS425197 (SP-4-3)-Diammine[2-(hydroxy-κO)acetato(2-)-κO]platinum ≥98% 100mg $57 2021-12-16 Buy
Arctom AS425197 (SP-4-3)-Diammine[2-(hydroxy-κO)acetato(2-)-κO]platinum ≥98% 250mg $89 2021-12-16 Buy
Arctom AS425197 (SP-4-3)-Diammine[2-(hydroxy-κO)acetato(2-)-κO]platinum ≥98% 1g $217 2021-12-16 Buy
Cayman Chemical 29001 Nedaplatin 25mg $86 2024-03-01 Buy
Cayman Chemical 29001 Nedaplatin 50mg $152 2024-03-01 Buy
Cayman Chemical 29001 Nedaplatin 100mg $287 2024-03-01 Buy
Cayman Chemical 29001 Nedaplatin 250mg $671 2024-03-01 Buy

Properties

storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :H2O : 13.6 mg/mL (44.86 mM; Need ultrasonic and warming; DMSO can inactivate Nedaplatin's activity)DMF : < 1 mg/mL (insoluble; DMSO can inactivate Nedaplatin's activity)
form :Powder
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Nedaplatin, a novel second generation platinum complex, was marketed in Japan for the treatment of a variety of cancers including: head and neck, small-cell and non-small cell lung, oesophageal, prostatic, testicular, ovarian, cervical, bladder, and uterine cancers. Platinum anticancer agents, prototyped by cisplatin, have been reported to be hydrolyzed to the mono- or diaquated species of diamine platinum which react with nucleophilic sites on DNA to cause intrastrand and interstrand crosslinks and DNA-protein crosslinks, which result in cytotoxicity. Nedaplatin was reportedly more active than cisplatin against several solid tumors while sharing less nephro- and gastrointestinal toxicity to cisplatin in viva The minimal renal toxicity displayed by nedaplatin allows its use in patients with deteriorated renal function.

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