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ChemicalBook >> CAS DataBase List >> Dexrazoxane

Dexrazoxane

Dexrazoxane price.
  • $5 - $1224
  • Product name: Dexrazoxane
  • CAS: 24584-09-6
  • MF: C11H16N4O4
  • MW: 268.27
  • EINECS:206-169-7
  • MDL Number:MFCD00866449
  • Synonyms:DEXRAZOXANE;(s)-4,4'-(1-methyl-1,2-ethanediyl)bis-2,6-piperazinedione;4’-(1-methyl-1,2-ethanediyl)bis-6-piperazinedion(+)-4 ;4’-propylenedi-6-piperazinedion(+)-4 ;adr529 ;cardioxane ;DEXTRAZOXANE;DEXTRORAZOXANE
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  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
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  • Biorbyt Ltd
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  • ManufacturerAK Scientific
  • Product numberJ90038
  • Product descriptionDexrazoxane
  • Packaging5g
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA170417
  • Product descriptionDexrazoxane 98+%
  • Packaging1mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA170417
  • Product descriptionDexrazoxane 98+%
  • Packaging10mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA170417
  • Product descriptionDexrazoxane 98+%
  • Packaging50mg
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA170417
  • Product descriptionDexrazoxane 98+%
  • Packaging100mg
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA170417
  • Product descriptionDexrazoxane 98+%
  • Packaging250mg
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA170417
  • Product descriptionDexrazoxane 98+%
  • Packaging1g
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA170417
  • Product descriptionDexrazoxane 98+%
  • Packaging5g
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006306
  • Product descriptionDEXRAZOXANE 95.00%
  • Packaging10MG
  • Price$653.68
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3407
  • Product descriptionDexrazoxane
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3407
  • Product descriptionDexrazoxane
  • Packaging100mg
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS008006
  • Product descriptionDexrazoxane ≥98%
  • Packaging10mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS008006
  • Product descriptionDexrazoxane ≥98%
  • Packaging50mg
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS008006
  • Product descriptionDexrazoxane ≥98%
  • Packaging100mg
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS008006
  • Product descriptionDexrazoxane ≥98%
  • Packaging250mg
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS008006
  • Product descriptionDexrazoxane ≥98%
  • Packaging1g
  • Price$85
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J90038 Dexrazoxane 5g $600 2021-12-16 Buy
Ambeed A170417 Dexrazoxane 98+% 1mg $5 2021-12-16 Buy
Ambeed A170417 Dexrazoxane 98+% 10mg $13 2021-12-16 Buy
Ambeed A170417 Dexrazoxane 98+% 50mg $19 2021-12-16 Buy
Ambeed A170417 Dexrazoxane 98+% 100mg $23 2021-12-16 Buy
Ambeed A170417 Dexrazoxane 98+% 250mg $34 2021-12-16 Buy
Ambeed A170417 Dexrazoxane 98+% 1g $86 2021-12-16 Buy
Ambeed A170417 Dexrazoxane 98+% 5g $290 2021-12-16 Buy
American Custom Chemicals Corporation API0006306 DEXRAZOXANE 95.00% 10MG $653.68 2021-12-16 Buy
ApexBio Technology B3407 Dexrazoxane 10mg $50 2021-12-16 Buy
ApexBio Technology B3407 Dexrazoxane 100mg $360 2021-12-16 Buy
Arctom AS008006 Dexrazoxane ≥98% 10mg $13 2021-12-16 Buy
Arctom AS008006 Dexrazoxane ≥98% 50mg $19 2021-12-16 Buy
Arctom AS008006 Dexrazoxane ≥98% 100mg $23 2021-12-16 Buy
Arctom AS008006 Dexrazoxane ≥98% 250mg $34 2021-12-16 Buy
Arctom AS008006 Dexrazoxane ≥98% 1g $85 2021-12-16 Buy

Properties

Melting point :194-196°C
alpha :D +11.35° (c = 5 in DMF)
Boiling point :531.5±50.0 °C(Predicted)
Density :1.333±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :powder
pka :2.1(at 25℃)
color :white to off-white
Merck :14,8123
InChIKey :BMKDZUISNHGIBY-ZETCQYMHSA-N
CAS DataBase Reference :24584-09-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Dexrazoxane is an intracellular iron chelator and an inhibitor of topoisomerase IIα. Through these activities, dexazoxane is highly protective in reducing anthracycline-induced cardiotoxicity and extravasation injury. Dexrazoxane has also been shown to act as an antioxidant that scavenges hydroxyl (IC50 = 2.1 mM), superoxide (IC50 = 0.4 mM), lipid (IC50 = 4.4 mM), 2,2-diphenyl-1-picrylhydrazyl (IC50 = 3.5 μM), and 2,2’-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (IC50 = 3.8 mM) free radicals.

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