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ChemicalBook >> CAS DataBase List >> NVP-TNKS656

NVP-TNKS656

NVP-TNKS656 price.
  • $57 - $2930
  • Product name: NVP-TNKS656
  • CAS: 1419949-20-4
  • MF: C27H34N4O5
  • MW: 494.58
  • EINECS:604-604-1
  • MDL Number:MFCD28167762
  • Synonyms:NVP-TNKS656;TNKS656;N-(cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-3,5,7,8-tetrahydro-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl)acetamide;NVP-TNKS656 - TNKS 656;TNKS656; TNKS-656;TNKS 656;CS-1333;N-(cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-4,5,7,8-tetrahydro-3H-pyrano[4,3-d]pyrimidin-2-yl)methyl)acetamide;1-Piperidineacetamide, N-(cyclopropylmethyl)-4-(4-methoxybenzoyl)-N-[(3,5,7,8-tetrahydro-4-oxo-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl]-
32 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 500μg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 10mM(in 1mL DMSO)
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number7527EM
  • Product descriptionNvp-tnks656
  • Packaging5mg
  • Price$556
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA474769
  • Product descriptionNVP-TNKS656 98+%
  • Packaging1mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA474769
  • Product descriptionNVP-TNKS656 98+%
  • Packaging5mg
  • Price$208
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA474769
  • Product descriptionNVP-TNKS656 98+%
  • Packaging10mg
  • Price$353
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA474769
  • Product descriptionNVP-TNKS656 98+%
  • Packaging25mg
  • Price$599
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004719
  • Product descriptionNVP-TNKS656 95.00%
  • Packaging5MG
  • Price$499.53
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6046
  • Product descriptionNVP-TNKS656
  • Packaging2mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6046
  • Product descriptionNVP-TNKS656
  • Packaging5mg
  • Price$345
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6046
  • Product descriptionNVP-TNKS656
  • Packaging10mM(in 1mL DMSO)
  • Price$376
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6046
  • Product descriptionNVP-TNKS656
  • Packaging10mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6046
  • Product descriptionNVP-TNKS656
  • Packaging25mg
  • Price$1080
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6046
  • Product descriptionNVP-TNKS656
  • Packaging50mg
  • Price$1800
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6046
  • Product descriptionNVP-TNKS656
  • Packaging100mg
  • Price$2930
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2599
  • Product descriptionNVP-TNKS656-TNKS656 99%
  • Packaging25mg
  • Price$588.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19930
  • Product descriptionNVP-TNKS656 ≥98%
  • Packaging500μg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19930
  • Product descriptionNVP-TNKS656 ≥98%
  • Packaging1mg
  • Price$100
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7527EM Nvp-tnks656 5mg $556 2021-12-16 Buy
Ambeed A474769 NVP-TNKS656 98+% 1mg $59 2021-12-16 Buy
Ambeed A474769 NVP-TNKS656 98+% 5mg $208 2021-12-16 Buy
Ambeed A474769 NVP-TNKS656 98+% 10mg $353 2021-12-16 Buy
Ambeed A474769 NVP-TNKS656 98+% 25mg $599 2021-12-16 Buy
American Custom Chemicals Corporation INB0004719 NVP-TNKS656 95.00% 5MG $499.53 2021-12-16 Buy
ApexBio Technology B6046 NVP-TNKS656 2mg $150 2021-12-16 Buy
ApexBio Technology B6046 NVP-TNKS656 5mg $345 2021-12-16 Buy
ApexBio Technology B6046 NVP-TNKS656 10mM(in 1mL DMSO) $376 2021-12-16 Buy
ApexBio Technology B6046 NVP-TNKS656 10mg $600 2021-12-16 Buy
ApexBio Technology B6046 NVP-TNKS656 25mg $1080 2021-12-16 Buy
ApexBio Technology B6046 NVP-TNKS656 50mg $1800 2021-12-16 Buy
ApexBio Technology B6046 NVP-TNKS656 100mg $2930 2021-12-16 Buy
Axon Medchem Axon2599 NVP-TNKS656-TNKS656 99% 25mg $588.5 2021-12-16 Buy
Cayman Chemical 19930 NVP-TNKS656 ≥98% 500μg $57 2024-03-01 Buy
Cayman Chemical 19930 NVP-TNKS656 ≥98% 1mg $100 2024-03-01 Buy

Properties

Boiling point :700.7±70.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :6.66±0.10(Predicted)
color :White to light yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

NVP-TNKS656 is an orally bioavailable inhibitor of tankyrase 2 (TNKS2; IC50 = 6 nM). It is selective for TNKS2 over poly(ADP-ribose) polymerase (PARP) 1 and 2 (IC50s = >19 and 32 nM, respectively). NVP-TNKS656 inhibits Wnt ligand-induced signaling with an IC50 value of 3.5 nM in an HEK293 cell reporter assay. In vivo, NVP-TNKS656 (350 mg/kg) reduces Axin 2 mRNA expression, a Wnt/β-catenin target gene, in MMTV-Wnt1 tumor bearing mice.

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