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Featured Products
Axon 2599
CAS [1419949-20-4]
MF C27H34N4O5MW 494.58
Highly potent, selective and orally active tankyrase inhibitor and antagonist of Wnt pathway activity in the MMTV-Wnt1 mouse xenograft model (IC50 values 0.0155 µM and 0.0060 µM for TNKS1 and TNKS2, respectively and >5000-fold selectivity over PARP1 and PARP2).
KEYWORDS: NVP-TNKS656 | Supplier | Wnt/TNKS inhibitor | TNKS 656 | NVP-TNKS 656 | NVPTNKS656 | TNKS656 | CAS [1419949-20-4] | DNA-RNA | TNKS1 | TNKS2 | PARP | Wnt | XAV939 | KRAS-mutant
N-(cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-4,5,7,8-tetrahydro-3H-pyrano[4,3-d]pyrimidin-2-yl)methyl)acetamide
[1419949-20-4]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue 2021 Spring Edition
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