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ChemicalBook >> CAS DataBase List >> NAPHTHOFLUORESCEIN

NAPHTHOFLUORESCEIN

NAPHTHOFLUORESCEIN price.
  • $32 - $969.6
  • Product name: NAPHTHOFLUORESCEIN
  • CAS: 61419-02-1
  • MF: C28H16O5
  • MW: 432.42
  • EINECS:634-716-5
  • MDL Number:MFCD00329026
  • Synonyms:NAPHTHOFLUORESCEIN;NAPHTHOFLUORESCEIN, FOR FLUORESCENCE;NAPHTHOFLUORESCEIN FOR FLUORESCENCE 95+%;Naphthafluorescein;Spiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one,3,11-dihydroxy-
11 prices
Selected condition：
Brand
  • AK Scientific
  • Alichem
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
Package
  • 1MG
  • 5MG
  • 10mg
  • 50mg
  • 100mg
  • 500mg
  • 1g
  • ManufacturerAK Scientific
  • Product number1910AH
  • Product descriptionNaphthofluorescein
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number61419021
  • Product description2-(11-Hydroxy-3-oxo-3H-dibenzo[c,h]xanthen-7-yl)benzoicacid
  • Packaging1g
  • Price$969.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberFRL0000171
  • Product descriptionNAPHTHOFLUORESCEIN 95.00%
  • Packaging1MG
  • Price$416
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberFRL0000171
  • Product descriptionNAPHTHOFLUORESCEIN 95.00%
  • Packaging5MG
  • Price$426
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberFRL0000171
  • Product descriptionNAPHTHOFLUORESCEIN 95.00%
  • Packaging10MG
  • Price$452
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13055
  • Product descriptionNaphthofluorescein ≥98%
  • Packaging5mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13055
  • Product descriptionNaphthofluorescein ≥98%
  • Packaging10mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13055
  • Product descriptionNaphthofluorescein ≥98%
  • Packaging50mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number70420
  • Product descriptionNaphthofluorescein suitable for fluorescence
  • Packaging100mg
  • Price$85.7
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number70420
  • Product descriptionNaphthofluorescein suitable for fluorescence
  • Packaging500mg
  • Price$311
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberN369013
  • Product descriptionNaphthofluorescein
  • Packaging1mg
  • Price$45
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1910AH Naphthofluorescein 10mg $160 2021-12-16 Buy
Alichem 61419021 2-(11-Hydroxy-3-oxo-3H-dibenzo[c,h]xanthen-7-yl)benzoicacid 1g $969.6 2021-12-16 Buy
American Custom Chemicals Corporation FRL0000171 NAPHTHOFLUORESCEIN 95.00% 1MG $416 2021-12-16 Buy
American Custom Chemicals Corporation FRL0000171 NAPHTHOFLUORESCEIN 95.00% 5MG $426 2021-12-16 Buy
American Custom Chemicals Corporation FRL0000171 NAPHTHOFLUORESCEIN 95.00% 10MG $452 2021-12-16 Buy
Cayman Chemical 13055 Naphthofluorescein ≥98% 5mg $32 2024-03-01 Buy
Cayman Chemical 13055 Naphthofluorescein ≥98% 10mg $57 2024-03-01 Buy
Cayman Chemical 13055 Naphthofluorescein ≥98% 50mg $214 2024-03-01 Buy
Sigma-Aldrich 70420 Naphthofluorescein suitable for fluorescence 100mg $85.7 2024-03-01 Buy
Sigma-Aldrich 70420 Naphthofluorescein suitable for fluorescence 500mg $311 2024-03-01 Buy
TRC N369013 Naphthofluorescein 1mg $45 2021-12-16 Buy

Properties

Melting point :189 °C (dec.)(lit.)
Boiling point :755.5±60.0 °C(Predicted)
Density :1.58±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: soluble
form :A crystalline solid
pka :8.82±0.20(Predicted)
color :Purple to purplish red
BRN :61335
InChIKey :IXQIUDNVFVTQLJ-UHFFFAOYSA-N
EPA Substance Registry System :

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Furin is a proprotein convertase, converting precursor proteins to functional proteins within the Golgi/trans-Golgi secretory pathway. Naphthofluorescein is a cell-permeable inhibitor of furin (IC50 = 12 μM). It inhibits furin-mediated cleavage of the pro-form of membrane type-1 matrix metalloproteinase MT1-MMP, resulting in decreased levels of active MT1-MMP. This, in turn, suppresses MMP-2 activation and reduces cell motility in CHO cells expressing proMT1-MMP. Napthofluorescein significantly inhibits the invasion of Matrigel by the human fibrosarcoma cell line, HT1080. The effects of this furin inhibitor on other furin-mediated processes, in vivo or in vitro, remain to be determined.

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