Lometrexol
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- $97 - $1395
- Product name: Lometrexol
- CAS: 106400-81-1
- MF: C21H25N5O6
- MW: 443.45
- EINECS:
- MDL Number:
- Synonyms:Lometrexol;(6R)-5,10-Dideaza-5,6,7,8-tetrahydrofolic acid;N-[4-[2-[[(6R)-2-Amino-3,4,5,6,7,8-hexahydro-4-oxopyrido[2,3-d]pyrimidin]-6-yl]ethyl]benzoyl]-L-glutamic acid;N-[4-[2-[[(R)-2-Amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin]-6-yl]ethyl]benzoyl]-L-glutamic acid;L-Glutamic acid, N-(4-(2-((6R)-2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-D)pyrimidin-6-yl)ethyl)benzoyl)-;L-Glutamic acid, N-(4-(2-(2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-D)pyrimidin-6-yl)ethyl)benzoyl)-, (R)-;Lometrexolum;Lometrexolum [inn-latin]
11 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Sigma-Aldrich
Package
- 1mg
- 5MG
- 10mg
- 25mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0027262
- Product descriptionLOMETREXOL HYDRATE 95.00%
- Packaging5MG
- Price$500.35
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18049
- Product descriptionLometrexol ≥98%
- Packaging1mg
- Price$97
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18049
- Product descriptionLometrexol ≥98%
- Packaging5mg
- Price$243
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0003423
- Product descriptionLometrexol
- Packaging1mg
- Price$275
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0003423
- Product descriptionLometrexol
- Packaging5mg
- Price$830
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0108147
- Product descriptionLometrexol hydrate 99.20%
- Packaging5mg
- Price$830
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0108147
- Product descriptionLometrexol hydrate 99.20%
- Packaging10mg
- Price$1395
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0003423
- Product descriptionLometrexol
- Packaging10mg
- Price$1395
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number27666
- Product descriptionLometrexol hydrate >95%
- Packaging1mg
- Price$990
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0040
- Product descriptionLometrexol hydrate ≥95% (HPLC)
- Packaging5mg
- Price$254
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0040
- Product descriptionLometrexol hydrate ≥95% (HPLC)
- Packaging25mg
- Price$666
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0027262 | LOMETREXOL HYDRATE 95.00% | 5MG | $500.35 | 2021-12-16 | Buy |
| Cayman Chemical | 18049 | Lometrexol ≥98% | 1mg | $97 | 2024-03-01 | Buy |
| Cayman Chemical | 18049 | Lometrexol ≥98% | 5mg | $243 | 2024-03-01 | Buy |
| ChemScene | CS-0003423 | Lometrexol | 1mg | $275 | 2021-12-16 | Buy |
| ChemScene | CS-0003423 | Lometrexol | 5mg | $830 | 2021-12-16 | Buy |
| ChemScene | CS-0108147 | Lometrexol hydrate 99.20% | 5mg | $830 | 2021-12-16 | Buy |
| ChemScene | CS-0108147 | Lometrexol hydrate 99.20% | 10mg | $1395 | 2021-12-16 | Buy |
| ChemScene | CS-0003423 | Lometrexol | 10mg | $1395 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 27666 | Lometrexol hydrate >95% | 1mg | $990 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML0040 | Lometrexol hydrate ≥95% (HPLC) | 5mg | $254 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0040 | Lometrexol hydrate ≥95% (HPLC) | 25mg | $666 | 2024-03-01 | Buy |
Properties
Density :1.56±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL
pka :3.60±0.10(Predicted)
form :powder
color :white to light yellow
Stability :Hygroscopic
storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL
pka :3.60±0.10(Predicted)
form :powder
color :white to light yellow
Stability :Hygroscopic
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Glycinamide ribonucleotide formyltransferase (GART) is a folate-dependent enzyme required for de novo purine synthesis. Lometrexol is a folate analog antimetabolite with antineoplastic activity. At nanomolar conentrations, it inhibits GART preventing de novo purine synthesis, inhibiting DNA synthesis, arresting cells in the S phase of the cell cycle, and inhibiting tumor cell proliferation.Related product price
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