| Identification | Back Directory | [Name]
Lometrexol | [CAS]
106400-81-1 | [Synonyms]
LY 264618
Lometrexol
Lometrexolum
LY 264618 hydrate
Lometrexol hydrate
Lometrexol(LY 264618)
Lometrexolum [inn-latin]
(6R)-5,10-Dideaza-5,6,7,8-tetrahydrofolic acid
N-[4-[2-[[(R)-2-Amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin]-6-yl]ethyl]benzoyl]-L-glutamic acid
L-Glutamic acid, N-(4-(2-((6R)-2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-D)pyrimidin-6-yl)ethyl)benzoyl)-
N-[4-[2-[[(6R)-2-Amino-3,4,5,6,7,8-hexahydro-4-oxopyrido[2,3-d]pyrimidin]-6-yl]ethyl]benzoyl]-L-glutamic acid
L-Glutamic acid, N-[4-[2-[(6R)-2-amino-3,4,5,6,7,8-hexahydro-4-oxopyrido[2,3-d]pyrimidin-6-yl]ethyl]benzoyl]-
L-Glutamic acid, N-(4-(2-(2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-D)pyrimidin-6-yl)ethyl)benzoyl)-, (R)-
N-[4-[2-[(6R)-2-amino-3,4,5,6,7,8-hexahydro-4-oxopyrido[2,3-d]pyrimidin-6-yl]ethyl]benzoyl]-L-glutamic acid hydrate | [Molecular Formula]
C21H25N5O6 | [MOL File]
106400-81-1.mol | [Molecular Weight]
443.45 |
| Chemical Properties | Back Directory | [density ]
1.56±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: ≥5mg/mL | [form ]
powder | [pka]
3.60±0.10(Predicted) | [color ]
white to light yellow |
| Hazard Information | Back Directory | [Uses]
It is an antifolate which inhibits glycinamide ribonucleotide formyltransferase (GARFT), an enzyme essential for de novo purine synthesis. |
|
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LGM Pharma
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Sigma-Aldrich
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DC Chemicals
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MedChemExpress
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