L-AP4
|
- $56 - $1290
- Product name: L-AP4
- CAS: 23052-81-5
- MF: C4H10NO5P
- MW: 183.1
- EINECS:200-258-5
- MDL Number:MFCD00083244
- Synonyms:L-AP4;L(+)-2-AMINO-4-PHOSPHONOBUTANOIC ACID;L-(+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID;L-(+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID (L-AP4);L(+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID 97%;(2S)-2-Amino-4-phosphonobutyric acid;(S)-4-Phosphono-2-aminobutanoic acid;(S)-4-Phosphono-2-aminobutyric acid
27 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- ApexBio Technology
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 10μg
- 50μG
- 0.5mg
- 5mg
- 50
- 1mg
- 10mg
- 25mg
- 50mg
- ManufacturerAK Scientific
- Product number3480AL
- Product descriptionL-Ap4
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3480AL
- Product descriptionL-Ap4
- Packaging50mg
- Price$640
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64075
- Product description(S)-(+)-2-Amino-4-phosphonobutyric acid, 99%
- Packaging1mg
- Price$93.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64075
- Product description(S)-(+)-2-Amino-4-phosphonobutyric acid, 99%
- Packaging10mg
- Price$216.65
- Updated2024-03-01
- Buy
- ManufacturerApexBio Technology
- Product numberB6202
- Product descriptionL-AP4
- Packaging10mg
- Price$308
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6202
- Product descriptionL-AP4
- Packaging50mg
- Price$1290
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb530414
- Product descriptionGDF5
- Packaging10μg
- Price$822.8
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA01291
- Product descriptionL-AP4
- Packaging10mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA01291
- Product descriptionL-AP4
- Packaging50mg
- Price$437.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14538
- Product descriptionL-AP4 ≥99%
- Packaging1mg
- Price$56
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14538
- Product descriptionL-AP4 ≥99%
- Packaging5mg
- Price$97
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14538
- Product descriptionL-AP4 ≥99%
- Packaging10mg
- Price$166
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14538
- Product descriptionL-AP4 ≥99%
- Packaging50mg
- Price$689
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0020419
- Product descriptionL-AP4 >99.0%
- Packaging5mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0020419
- Product descriptionL-AP4 >99.0%
- Packaging10mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD21010145
- Product description(S)-2-Amino-4-phosphonobutanoicacid 97%
- Packaging1mg
- Price$89
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3480AL | L-Ap4 | 10mg | $218 | 2021-12-16 | Buy |
| AK Scientific | 3480AL | L-Ap4 | 50mg | $640 | 2021-12-16 | Buy |
| Alfa Aesar | J64075 | (S)-(+)-2-Amino-4-phosphonobutyric acid, 99% | 1mg | $93.65 | 2024-03-01 | Buy |
| Alfa Aesar | J64075 | (S)-(+)-2-Amino-4-phosphonobutyric acid, 99% | 10mg | $216.65 | 2024-03-01 | Buy |
| ApexBio Technology | B6202 | L-AP4 | 10mg | $308 | 2021-12-16 | Buy |
| ApexBio Technology | B6202 | L-AP4 | 50mg | $1290 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb530414 | GDF5 | 10μg | $822.8 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA01291 | L-AP4 | 10mg | $125 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA01291 | L-AP4 | 50mg | $437.5 | 2021-12-16 | Buy |
| Cayman Chemical | 14538 | L-AP4 ≥99% | 1mg | $56 | 2024-03-01 | Buy |
| Cayman Chemical | 14538 | L-AP4 ≥99% | 5mg | $97 | 2024-03-01 | Buy |
| Cayman Chemical | 14538 | L-AP4 ≥99% | 10mg | $166 | 2024-03-01 | Buy |
| Cayman Chemical | 14538 | L-AP4 ≥99% | 50mg | $689 | 2024-03-01 | Buy |
| ChemScene | CS-0020419 | L-AP4 >99.0% | 5mg | $240 | 2021-12-16 | Buy |
| ChemScene | CS-0020419 | L-AP4 >99.0% | 10mg | $400 | 2021-12-16 | Buy |
| Crysdot | CD21010145 | (S)-2-Amino-4-phosphonobutanoicacid 97% | 1mg | $89 | 2021-12-16 | Buy |
Properties
Melting point :207-215 °C
Boiling point :491.7±55.0 °C(Predicted)
Density :1.628±0.06 g/cm3(Predicted)
storage temp. :0-6°C
solubility :H2O : 50 mg/mL (273.07 mM; Need ultrasonic)
pka :2.19±0.10(Predicted)
form :solid
color :White
Water Solubility :Soluble to 5 mM in water and to 100 mM in 1eq. NaOH
Sensitive :Light Sensitive
CAS DataBase Reference :23052-81-5(CAS DataBase Reference)
Boiling point :491.7±55.0 °C(Predicted)
Density :1.628±0.06 g/cm3(Predicted)
storage temp. :0-6°C
solubility :H2O : 50 mg/mL (273.07 mM; Need ultrasonic)
pka :2.19±0.10(Predicted)
form :solid
color :White
Water Solubility :Soluble to 5 mM in water and to 100 mM in 1eq. NaOH
Sensitive :Light Sensitive
CAS DataBase Reference :23052-81-5(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
|
||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||||||||||||||||
| Hazard statements: |
|
||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Metabotropic glutamate receptors (mGluR) function to modulate excitatory synaptic transmission in the brain. Eight subtypes (1-8) and multiple splice variants of the mGluR have been identified and grouped based on their pharmacological properties. Group I mGluRs (subtypes 1 and 5) activate the phosphatidyl inositol pathway, while Group II (2 and 3) and Group III (4, 6, 7, and 8) inhibit adenylyl cyclase. L-AP4, an analog of L-glutamic acid, is a selective Group III mGluR agonist that functions presynaptically to suppress glutamate release (IC50 = 2.5 μM). L-AP4 has been shown to depress synaptic transmission in glutamatergic pathways in the hippocampus, olfactory bulb, and retina as well as act as an agonist at the quisqualate-sensitized AP6 site in hippocampus.More related product prices
(S)-2-Amino-2-methyl-4-phosphonobutanoic acid 20263-07-4 1,2-Diaminopropane L-AP4Related product price
- (S)-2-Amino-2-methyl-4-phosphonobutanoic acid
$45-1362 - 20263-07-4
$102-1170 - 13138-33-5
$37-1519.98
