Ilomastat
- $32 - $5661
- Product name: Ilomastat
- CAS: 142880-36-2
- MF: C20H28N4O4
- MW: 388.46
- EINECS:
- MDL Number:MFCD00917040
- Synonyms:(2R)-N4-Hydroxy-N1-[(1S)-1-(1H-indol-3-ylmethyl)-2-(methylamino)-2-oxoethyl]-2-(2-methylpropyl)-butanediamide Ilomastat (GM6001, Galardin);Galardin CS 610;Ilomastat, >=98%;(r)-n4-hydroxy-n1-[(s)-2-(1h-indol-3-yl)-1-methylcarbamoly-ethyl]-2-isobutyl-succinamide;galardin tm;(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide;Galardin, GM6001, Ilomastat;SANTACRUZ
39 prices
Selected condition:
Brand
- Alfa Aesar
- Ambeed
- ApexBio Technology
- Arctom
- Ark Pharm
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 500μg
- 1mg
- 2mg
- 2.5mg
- 5mg
- 10mg
- 50mg
- 100mg
- 250mg
- 1000mg
- 1g
- ManufacturerAlfa Aesar
- Product numberJ65687
- Product descriptionGM 6001
- Packaging1mg
- Price$81.1
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ65687
- Product descriptionGM 6001
- Packaging5mg
- Price$366
- Updated2023-06-20
- Buy
- ManufacturerAmbeed
- Product numberA237914
- Product descriptionGM 6001 98%
- Packaging2mg
- Price$57
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA237914
- Product descriptionGM 6001 98%
- Packaging5mg
- Price$74
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA237914
- Product descriptionGM 6001 98%
- Packaging10mg
- Price$122
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA237914
- Product descriptionGM 6001 98%
- Packaging50mg
- Price$407
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA237914
- Product descriptionGM 6001 98%
- Packaging100mg
- Price$666
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA237914
- Product descriptionGM 6001 98%
- Packaging1g
- Price$5661
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4050
- Product descriptionGM 6001
- Packaging5mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS488887
- Product descriptionGM 6001 ≥98%
- Packaging2mg
- Price$56
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS488887
- Product descriptionGM 6001 ≥98%
- Packaging5mg
- Price$73
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS488887
- Product descriptionGM 6001 ≥98%
- Packaging10mg
- Price$121
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS488887
- Product descriptionGM 6001 ≥98%
- Packaging50mg
- Price$403
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS488887
- Product descriptionGM 6001 ≥98%
- Packaging100mg
- Price$659
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberAK468728
- Product descriptionGM 6001 98%
- Packaging2mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberAK468728
- Product descriptionGM 6001 98%
- Packaging10mg
- Price$244
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Alfa Aesar | J65687 | GM 6001 | 1mg | $81.1 | 2021-12-16 | Buy |
Alfa Aesar | J65687 | GM 6001 | 5mg | $366 | 2023-06-20 | Buy |
Ambeed | A237914 | GM 6001 98% | 2mg | $57 | 2021-12-16 | Buy |
Ambeed | A237914 | GM 6001 98% | 5mg | $74 | 2021-12-16 | Buy |
Ambeed | A237914 | GM 6001 98% | 10mg | $122 | 2021-12-16 | Buy |
Ambeed | A237914 | GM 6001 98% | 50mg | $407 | 2021-12-16 | Buy |
Ambeed | A237914 | GM 6001 98% | 100mg | $666 | 2021-12-16 | Buy |
Ambeed | A237914 | GM 6001 98% | 1g | $5661 | 2021-12-16 | Buy |
ApexBio Technology | A4050 | GM 6001 | 5mg | $100 | 2021-12-16 | Buy |
Arctom | AS488887 | GM 6001 ≥98% | 2mg | $56 | 2021-12-16 | Buy |
Arctom | AS488887 | GM 6001 ≥98% | 5mg | $73 | 2021-12-16 | Buy |
Arctom | AS488887 | GM 6001 ≥98% | 10mg | $121 | 2021-12-16 | Buy |
Arctom | AS488887 | GM 6001 ≥98% | 50mg | $403 | 2021-12-16 | Buy |
Arctom | AS488887 | GM 6001 ≥98% | 100mg | $659 | 2021-12-16 | Buy |
Ark Pharm | AK468728 | GM 6001 98% | 2mg | $110 | 2021-12-16 | Buy |
Ark Pharm | AK468728 | GM 6001 98% | 10mg | $244 | 2021-12-16 | Buy |
Properties
Density :1.228±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO, and 100% ethanol.
pka :9.16±0.20(Predicted)
form :Off-white solid
color :White
Sensitive :Moisture Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :NITYDPDXAAFEIT-DYVFJYSZSA-N
storage temp. :2-8°C
solubility :Soluble in DMSO, and 100% ethanol.
pka :9.16±0.20(Predicted)
form :Off-white solid
color :White
Sensitive :Moisture Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :NITYDPDXAAFEIT-DYVFJYSZSA-N
Safety Information
Symbol(GHS): | ||||||||||||||||||||||
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Signal word: | Warning | |||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs). It inhibits zinc-containing thermolysin and elastase from P. aeruginosa, both with Ki values of 20 nM. GM 6001 inhibits MMP-1, -2, -7, -8, -9, -12, -13, -14, -16, and -26 with Ki or IC50 values between 0.1 and 10 nM. It inhibits disintegrin and metalloproteinase domain-containing (ADAM) proteins ADAM9, ADAM10, ADAM12, and ADAM17 at nanomolar concentrations. It less potently inhibits lethal factor from B. anthracis anthrax lethal toxin (Ki = 2.74 μM). GM 6001 also impairs the growth of the human pathogen Chlamydia by inhibiting peptide deformylase, which contains iron rather than zinc (IC50 = 38 nM).More related product prices
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