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ChemicalBook >> CAS DataBase List >> Halobetasol propionate

Halobetasol propionate

Halobetasol propionate price.
  • $32 - $1593.9
  • Product name: Halobetasol propionate
  • CAS: 66852-54-8
  • MF: C25H31ClF2O5
  • MW: 484.96
  • EINECS:686-247-0
  • MDL Number:MFCD00866013
  • Synonyms:ulobetasol propionate;HALOBETASOL PROPIONATE;BMY-30056;CGP-14458;Uiobetasol Propionate;Ultravate;21-chloro-6alpha,9-difluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate;6 alpha-fluoroclobetasol 17-propionate
14 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10MG
  • 25mg
  • 50mg
  • 100MG
  • 200MG
  • 1g
  • ManufacturerAHH
  • Product numberMT-52277
  • Product descriptionHalobetasolpropionate 98%
  • Packaging1g
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberK097
  • Product descriptionHalobetasolpropionate
  • Packaging50mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberK097
  • Product descriptionHalobetasolpropionate
  • Packaging5mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002882
  • Product descriptionHALOBETASOL PROPIONATE 95.00%
  • Packaging100MG
  • Price$1593.9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002882
  • Product descriptionHALOBETASOL PROPIONATE 95.00%
  • Packaging10MG
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23781
  • Product descriptionHalobetasol Propionate ≥95%
  • Packaging5mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23781
  • Product descriptionHalobetasol Propionate ≥95%
  • Packaging10mg
  • Price$55
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23781
  • Product descriptionHalobetasol Propionate ≥95%
  • Packaging25mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23781
  • Product descriptionHalobetasol Propionate ≥95%
  • Packaging50mg
  • Price$169
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM201161
  • Product descriptionHalobetasolpropionate 98%
  • Packaging100mg
  • Price$107
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001115
  • Product descriptionHalobetasolpropionate 98+%
  • Packaging100mg
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001115
  • Product descriptionHalobetasolpropionate 98+%
  • Packaging50mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number1302906
  • Product descriptionHalobetasol propionate United States Pharmacopeia (USP) Reference Standard
  • Packaging200MG
  • Price$174.4
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberH102300
  • Product descriptionHalobetasolPropionate
  • Packaging25mg
  • Price$85
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-52277 Halobetasolpropionate 98% 1g $330 2021-12-16 Buy
AK Scientific K097 Halobetasolpropionate 50mg $138 2021-12-16 Buy
AK Scientific K097 Halobetasolpropionate 5mg $39 2021-12-16 Buy
American Custom Chemicals Corporation API0002882 HALOBETASOL PROPIONATE 95.00% 100MG $1593.9 2021-12-16 Buy
American Custom Chemicals Corporation API0002882 HALOBETASOL PROPIONATE 95.00% 10MG $704.55 2021-12-16 Buy
Cayman Chemical 23781 Halobetasol Propionate ≥95% 5mg $32 2024-03-01 Buy
Cayman Chemical 23781 Halobetasol Propionate ≥95% 10mg $55 2024-03-01 Buy
Cayman Chemical 23781 Halobetasol Propionate ≥95% 25mg $116 2024-03-01 Buy
Cayman Chemical 23781 Halobetasol Propionate ≥95% 50mg $169 2024-03-01 Buy
Chemenu CM201161 Halobetasolpropionate 98% 100mg $107 2021-12-16 Buy
Crysdot CD31001115 Halobetasolpropionate 98+% 100mg $104 2021-12-16 Buy
Crysdot CD31001115 Halobetasolpropionate 98+% 50mg $55 2021-12-16 Buy
Sigma-Aldrich 1302906 Halobetasol propionate United States Pharmacopeia (USP) Reference Standard 200MG $174.4 2024-03-01 Buy
TRC H102300 HalobetasolPropionate 25mg $85 2021-12-16 Buy

Properties

Melting point :213-215°C
Boiling point :570.7±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Dioxane (Sparingly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :12.55±0.70(Predicted)
color :White to Off-White
InChIKey :BDSYKGHYMJNPAB-QNGYMBKVNA-N
SMILES :O([C@@]1([C@H](C[C@@]2([H])[C@]3([H])C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C)C(=O)CCl)C(=O)CC |&1:1,2,4,6,9,17,19,21,24,r|
CAS DataBase Reference :66852-54-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P281 Use personal protective equipment as required.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P314 Get medical advice/attention if you feel unwell.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Halobetasol propionate is a new ultra-potent topical corticosteroid exhibiting both antiinflammatory and antihyperplasia properties. The compound is recommended for the treatment of moderate to severe corticosteroid-responsive dermatoses and appears to be particularly effective in patients with plaque psoriasis.  It inhibits dermatitis induced by ultraviolet light in guinea pigs (ED50 = 1.45 μg/animal) and by oxazolone in mice (ED50 = 0.8 μg/animal). Halobetasol propionate also has anti-inflammatory effects on croton oil-induced ear edema in rats (ED50s = 10 μg/ml and 0.5 μg/ear) and mice (ED50s = 1.2 and <0.32 μg/ear after 6 and 24 hours of treatment, respectively). Topical formulations containing halobetasol propionate have been used for inflammatory and pruritic dermatitis.

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