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ChemicalBook >> CAS DataBase List >> Ginkgolide B

Ginkgolide B

Ginkgolide B price.
  • $32 - $2355.15
  • Product name: Ginkgolide B
  • CAS: 15291-77-7
  • MF: C20H24O10
  • MW: 424.4
  • EINECS:604-876-0
  • MDL Number:MFCD05662347
  • Synonyms:7-DEOXYGINKGOLIDE C;BN 52021;GINKGOLIDE B;ginkgolide B from ginkgo leaves;(1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione;ginkgolide b from ginkgo biloba leaves;GinkgolideA,1-hydroxy-, (1β)-;Ginkgolide B, froM Ginkgo biloba
44 prices
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Brand
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • DC Chemicals
  • JR MediChem
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
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  • 100mg
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  • 500MG
  • 0.5g
  • 10
  • 1G
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-G0218-M050
  • Product descriptionGinkgolide B ≥98%(HPLC)
  • Packaging50mg
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1521
  • Product descriptionGinkgolide B 98%
  • Packaging0.5g
  • Price$430
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberO231
  • Product descriptionGinkgolide B
  • Packaging5mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60646
  • Product descriptionGinkgolide B
  • Packaging10mg
  • Price$97.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60646
  • Product descriptionGinkgolide B
  • Packaging50mg
  • Price$330.65
  • Updated2024-03-01
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002828
  • Product descriptionGINKGOLIDE B 95.00%
  • Packaging50MG
  • Price$721.88
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002828
  • Product descriptionGINKGOLIDE B 95.00%
  • Packaging500MG
  • Price$1732.5
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002828
  • Product descriptionGINKGOLIDE B 95.00%
  • Packaging1G
  • Price$2355.15
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberN1879
  • Product descriptionGinkgolide B
  • Packaging20mg
  • Price$50
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberSY073188
  • Product descriptionGinkgolideB,98%,fromGinkgobiloba ≥98%
  • Packaging10mg
  • Price$76.36
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberCFN99640
  • Product descriptionGinkgolide B
  • Packaging20mg
  • Price$70
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number1330
  • Product descriptionGinkgolide B
  • Packaging10mg
  • Price$35
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number1330
  • Product descriptionGinkgolide B
  • Packaging20mg
  • Price$55
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number1330
  • Product descriptionGinkgolide B
  • Packaging1g
  • Price$790
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545816
  • Product descriptionGinkgolide B >98%
  • Packaging10mg
  • Price$136
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb593951
  • Product descriptionGinkgolide B
  • Packaging20mg
  • Price$246.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-G0218-M050 Ginkgolide B ≥98%(HPLC) 50mg $124 2021-12-16 Buy
AHH API-1521 Ginkgolide B 98% 0.5g $430 2021-12-16 Buy
AK Scientific O231 Ginkgolide B 5mg $49 2021-12-16 Buy
Alfa Aesar J60646 Ginkgolide B 10mg $97.65 2024-03-01 Buy
Alfa Aesar J60646 Ginkgolide B 50mg $330.65 2024-03-01 Buy
American Custom Chemicals Corporation API0002828 GINKGOLIDE B 95.00% 50MG $721.88 2021-12-16 Buy
American Custom Chemicals Corporation API0002828 GINKGOLIDE B 95.00% 500MG $1732.5 2021-12-16 Buy
American Custom Chemicals Corporation API0002828 GINKGOLIDE B 95.00% 1G $2355.15 2021-12-16 Buy
ApexBio Technology N1879 Ginkgolide B 20mg $50 2021-12-16 Buy
Arctom SY073188 GinkgolideB,98%,fromGinkgobiloba ≥98% 10mg $76.36 2021-12-16 Buy
Arctom CFN99640 Ginkgolide B 20mg $70 2021-12-16 Buy
AvaChem 1330 Ginkgolide B 10mg $35 2021-12-16 Buy
AvaChem 1330 Ginkgolide B 20mg $55 2021-12-16 Buy
AvaChem 1330 Ginkgolide B 1g $790 2021-12-16 Buy
Biorbyt Ltd orb545816 Ginkgolide B >98% 10mg $136 2021-12-16 Buy
Biorbyt Ltd orb593951 Ginkgolide B 20mg $246.5 2021-12-16 Buy

Properties

Melting point :280°C (dec.)
alpha :D24 -52.6° (c = 1 in ethanol)
Boiling point :762.4±60.0 °C(Predicted)
Density :1?+-.0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 10 mg/ml).
pka :pKa1 7.14; pKa2 8.60; pKa3 11.89(at 25℃)
form :Solid
color :White
Water Solubility :Soluble in DMSO. Slightly soluble in water and ethanol
BRN :4727611
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
InChIKey :SQOJOAFXDQDRGF-MMQTXUMRSA-N
SMILES :[C@@]12(O)[C@]34C(=O)O[C@@H]5C[C@@H](C(C)(C)C)C6([C@@H](O)C(=O)O[C@@]6([H])O3)C45[C@H](O)[C@]1([H])OC(=O)[C@H]2C
LogP :2.070 (est)
CAS DataBase Reference :15291-77-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

Platelet-activating factor (PAF) is an important mediator of cell proliferation, angiogenesis, inflammatory response regulation, vasodilation, superoxide formation, and platelet aggregation. These cellular effects are mediated through its specific G-protein coupled receptor, PAFR. Ginkgolide B, a terpenoid extracted from G. biloba leaves, is a potent PAFR antagonist that inhibits platelet aggregation at concentrations from 10-500 μM. It has been shown to inhibit non-mucinous ovarian cancer proliferation by blocking cell cycling. Ginkgolide B also demonstrates number of other anti-inflammatory, anti-allergic, antioxidant, and neuroprotective effects.

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