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ChemicalBook >> CAS DataBase List >> Fluocinolone Acetonide

Fluocinolone Acetonide

Fluocinolone Acetonide price.
  • $55 - $1674.75
  • Product name: Fluocinolone Acetonide
  • CAS: 67-73-2
  • MF: C24H30F2O6
  • MW: 452.49
  • EINECS:200-668-5
  • MDL Number:MFCD00010525
  • Synonyms:(6-alpha,11-beta,16-alpha)-idene)bis(oxy)) ;(6alpha,11beta,16alpha)-idene)bis(oxy)) ;20-dione,6,9-difluoro-11,12-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-,(6-alpha,11-bpregna-4-diene-3 ;6alpha,9alpha-difluoro-16alpha-hydroxyprednisolone16,17-acetonide ;fluocinolone16,17-acetonide ;Fluocinoloneacetate ;fluovitif ;jellin
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  • AHH
  • AK Scientific
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  • ManufacturerAHH
  • Product numberMT-12902
  • Product descriptionFluocinolone acetonide 98%
  • Packaging5g
  • Price$828
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ93291
  • Product descriptionFluocinolone acetonide
  • Packaging1g
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ93291
  • Product descriptionFluocinolone acetonide
  • Packaging5g
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63996
  • Product descriptionFluocinolone acetonide
  • Packaging100mg
  • Price$55.7
  • Updated2023-06-20
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  • ManufacturerAlfa Aesar
  • Product numberJ63996
  • Product descriptionFluocinolone acetonide
  • Packaging1g
  • Price$294
  • Updated2023-06-20
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0006893
  • Product descriptionFLUOCINOLONE ACETONIDE 95.00%
  • Packaging1G
  • Price$1674.75
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberSY057543
  • Product description(6alpha,9alpha,11beta,16beta)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione ≥97%
  • Packaging250mg
  • Price$80
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberSY057543
  • Product description(6alpha,9alpha,11beta,16beta)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione ≥97%
  • Packaging1g
  • Price$95
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberSY057543
  • Product description(6alpha,9alpha,11beta,16beta)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione ≥97%
  • Packaging5g
  • Price$230
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberSY057543
  • Product description(6alpha,9alpha,11beta,16beta)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione ≥97%
  • Packaging10g
  • Price$350
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberSY057543
  • Product description(6alpha,9alpha,11beta,16beta)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione ≥97%
  • Packaging25g
  • Price$695
  • Updated2021-12-16
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  • ManufacturerAronis compounds
  • Product numberBBC/733
  • Product description4b,12-difluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
  • Packaging1g
  • Price$318
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFF15770
  • Product descriptionFluocinolone acetonide
  • Packaging1g
  • Price$55
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFF15770
  • Product descriptionFluocinolone acetonide
  • Packaging2g
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFF15770
  • Product descriptionFluocinolone acetonide
  • Packaging5G
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFF15770
  • Product descriptionFluocinolone acetonide
  • Packaging10g
  • Price$350
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-12902 Fluocinolone acetonide 98% 5g $828 2021-12-16 Buy
AK Scientific J93291 Fluocinolone acetonide 1g $55 2021-12-16 Buy
AK Scientific J93291 Fluocinolone acetonide 5g $195 2021-12-16 Buy
Alfa Aesar J63996 Fluocinolone acetonide 100mg $55.7 2023-06-20 Buy
Alfa Aesar J63996 Fluocinolone acetonide 1g $294 2023-06-20 Buy
American Custom Chemicals Corporation SHG0006893 FLUOCINOLONE ACETONIDE 95.00% 1G $1674.75 2021-12-16 Buy
Arctom SY057543 (6alpha,9alpha,11beta,16beta)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione ≥97% 250mg $80 2021-12-16 Buy
Arctom SY057543 (6alpha,9alpha,11beta,16beta)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione ≥97% 1g $95 2021-12-16 Buy
Arctom SY057543 (6alpha,9alpha,11beta,16beta)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione ≥97% 5g $230 2021-12-16 Buy
Arctom SY057543 (6alpha,9alpha,11beta,16beta)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione ≥97% 10g $350 2021-12-16 Buy
Arctom SY057543 (6alpha,9alpha,11beta,16beta)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione ≥97% 25g $695 2021-12-16 Buy
Aronis compounds BBC/733 4b,12-difluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one 1g $318 2021-12-16 Buy
Biosynth Carbosynth FF15770 Fluocinolone acetonide 1g $55 2021-12-16 Buy
Biosynth Carbosynth FF15770 Fluocinolone acetonide 2g $100 2021-12-16 Buy
Biosynth Carbosynth FF15770 Fluocinolone acetonide 5G $195 2021-12-16 Buy
Biosynth Carbosynth FF15770 Fluocinolone acetonide 10g $350 2021-12-16 Buy

Properties

Melting point :267-269 °C(lit.)
alpha :D +95° (chloroform)
Boiling point :578.5±50.0 °C(Predicted)
Density :1.1826 (estimate)
refractive index :103 ° (C=1, MeOH)
storage temp. :Refrigerator
solubility :Practically insoluble in water, soluble in acetone and in ethanol
pka :12.78±0.70(Predicted)
form :Solid
color :White to Off-White
Water Solubility :Soluble in water (partly), DMSO, alcohol, chloroform and methanol.
Merck :14,4150
InChIKey :FEBLZLNTKCEFIT-VSXGLTOVSA-N
CAS DataBase Reference :67-73-2(CAS DataBase Reference)
EPA Substance Registry System :Fluocinolone acetonide (67-73-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Fluocinolone acetonide is primarily used in dermatology to reduce skin inflammation and relieve itching. It acts as an inhibitor of tumor cells and it can regulate lipid metabolism by modulating gene expression. It can also inhibit the expression of VEGF (vascular endothelial growth factor) in the retinal pigment epithelial cell line due to its high glucocorticoid receptor affinity. Furthermore, it can inhibit TNF-α angiogenesis.

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