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ChemicalBook >> CAS DataBase List >> FGF-401

FGF-401

FGF-401 price.
  • $38 - $2400
  • Product name: FGF-401
  • CAS: 1708971-55-4
  • MF: C25H30N8O4
  • MW: 506.56
  • EINECS:-0
  • MDL Number:MFCD31381923
  • Synonyms:8-naphthyridine-1(2H)-carboxamide;0997;FGF-401;N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide;N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide;Roblitinib（FGF-401）;FGF 401;FGF-401;N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide
15 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 1mg
  • 2mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2323EF
  • Product descriptionRoblitinib
  • Packaging1mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0005698
  • Product descriptionN-(5-CYANO-4-((2-METHOXYETHYL)AMINO)PYRIDIN-2-YL)-7-FORMYL-6-((4-METHYL-2-OXOPIPERAZIN-1-YL)METHYL)-3,4-DIHYDRO-1,8-NAPHTHYRIDINE-1(2H)-CARBOXAMIDE 95.00%
  • Packaging5MG
  • Price$454.85
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23029
  • Product descriptionFGF401
  • Packaging1mg
  • Price$38
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23029
  • Product descriptionFGF401
  • Packaging5mg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23029
  • Product descriptionFGF401
  • Packaging10mg
  • Price$292
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23029
  • Product descriptionFGF401
  • Packaging25mg
  • Price$638
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6853
  • Product descriptionRoblitinib 99.33%
  • Packaging2mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6853
  • Product descriptionRoblitinib 99.33%
  • Packaging5mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6853
  • Product descriptionRoblitinib 99.33%
  • Packaging10mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6853
  • Product descriptionRoblitinib 99.33%
  • Packaging50mg
  • Price$690
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6853
  • Product descriptionRoblitinib 99.33%
  • Packaging100mg
  • Price$1170
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD00008110
  • Product descriptionFGF401 98+%
  • Packaging10mg
  • Price$168
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD00008110
  • Product descriptionFGF401 98+%
  • Packaging50mg
  • Price$535
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD00008110
  • Product descriptionFGF401 98+%
  • Packaging250mg
  • Price$1766
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10128
  • Product descriptionFGF401(Roblitinib) >98%
  • Packaging1g
  • Price$2400
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2323EF Roblitinib 1mg $139 2021-12-16 Buy
American Custom Chemicals Corporation INB0005698 N-(5-CYANO-4-((2-METHOXYETHYL)AMINO)PYRIDIN-2-YL)-7-FORMYL-6-((4-METHYL-2-OXOPIPERAZIN-1-YL)METHYL)-3,4-DIHYDRO-1,8-NAPHTHYRIDINE-1(2H)-CARBOXAMIDE 95.00% 5MG $454.85 2021-12-16 Buy
Cayman Chemical 23029 FGF401 1mg $38 2024-03-01 Buy
Cayman Chemical 23029 FGF401 5mg $166 2024-03-01 Buy
Cayman Chemical 23029 FGF401 10mg $292 2024-03-01 Buy
Cayman Chemical 23029 FGF401 25mg $638 2024-03-01 Buy
ChemScene CS-6853 Roblitinib 99.33% 2mg $95 2021-12-16 Buy
ChemScene CS-6853 Roblitinib 99.33% 5mg $130 2021-12-16 Buy
ChemScene CS-6853 Roblitinib 99.33% 10mg $210 2021-12-16 Buy
ChemScene CS-6853 Roblitinib 99.33% 50mg $690 2021-12-16 Buy
ChemScene CS-6853 Roblitinib 99.33% 100mg $1170 2021-12-16 Buy
Crysdot CD00008110 FGF401 98+% 10mg $168 2021-12-16 Buy
Crysdot CD00008110 FGF401 98+% 50mg $535 2021-12-16 Buy
Crysdot CD00008110 FGF401 98+% 250mg $1766 2021-12-16 Buy
DC Chemicals DC10128 FGF401(Roblitinib) >98% 1g $2400 2021-12-16 Buy

Properties

Boiling point :852.1±65.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:5.4(Max Conc. mg/mL);10.66(Max Conc. mM)
Chloroform:30.0(Max Conc. mg/mL);59.22(Max Conc. mM) form :A crystalline solid
pka :11.40±0.20(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

FGF401 is an inhibitor of FGF receptor 4 (FGFR4; IC50 = 1.9 nM). It inhibits proliferation of Huh7 carcinoma cells with an IC50 value of 12 nM. FGF401 induces bile acid synthesis in dogs, increasing plasma and fecal levels of bile acids when administered at a dose of 45 mg/kg per day for four weeks. It also decreases serum cholesterol when administered at doses ranging from 5 to 45 mg/kg per day.

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