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ChemicalBook >> CAS DataBase List >> Erlotinib

Erlotinib

Erlotinib price.
  • $5 - $1900
  • Product name: Erlotinib
  • CAS: 183321-74-6
  • MF: C22H23N3O4
  • MW: 393.44
  • EINECS:689-196-2
  • MDL Number:MFCD02089651
  • Synonyms:ERLOTINIB;ERLOTINIB HCL SALT;4-[(3-ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline;n-(3-ethynylphenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine;Erlotinib Hydrochloirde;4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-;ERLOTININ;N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine
47 prices
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Brand
  • AccelPharmtech
  • Activate Scientific
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Chemtos
  • Crysdot
  • DC Chemicals
Package
  • 25mg
  • 50mg
  • 1mg
  • 10mM(in 1mL DMSO)
  • 001
  • 100MG
  • 250mg
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  • 1g
  • 2g
  • 5G
  • 10g
  • 25G
  • ManufacturerAccelPharmtech
  • Product number093333
  • Product descriptionErlotinib 99%
  • Packaging001
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberAT7548
  • Product descriptionErlotinib 99%
  • Packaging25G
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS59585
  • Product descriptionErlotinib 95%
  • Packaging1g
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS59585
  • Product descriptionErlotinib 95%
  • Packaging5G
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberP443
  • Product descriptionErlotinib
  • Packaging1g
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121900
  • Product description4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+%
  • Packaging25mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121900
  • Product description4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+%
  • Packaging250mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121900
  • Product description4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+%
  • Packaging1g
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121900
  • Product description4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+%
  • Packaging5g
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121900
  • Product description4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+%
  • Packaging25g
  • Price$235
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024668
  • Product descriptionERLOTINIB 95.00%
  • Packaging100MG
  • Price$179.55
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024668
  • Product descriptionERLOTINIB 95.00%
  • Packaging500MG
  • Price$701.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024668
  • Product descriptionERLOTINIB 95.00%
  • Packaging1G
  • Price$752.14
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024668
  • Product descriptionERLOTINIB 95.00%
  • Packaging5G
  • Price$1325.59
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3397
  • Product descriptionErlotinib
  • Packaging1g
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3397
  • Product descriptionErlotinib
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AccelPharmtech 093333 Erlotinib 99% 001 $40 2021-12-16 Buy
AccelPharmtech AT7548 Erlotinib 99% 25G $180 2021-12-16 Buy
Activate Scientific AS59585 Erlotinib 95% 1g $42 2021-12-16 Buy
Activate Scientific AS59585 Erlotinib 95% 5G $155 2021-12-16 Buy
AK Scientific P443 Erlotinib 1g $27 2021-12-16 Buy
Ambeed A121900 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+% 25mg $5 2021-12-16 Buy
Ambeed A121900 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+% 250mg $7 2021-12-16 Buy
Ambeed A121900 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+% 1g $14 2021-12-16 Buy
Ambeed A121900 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+% 5g $55 2021-12-16 Buy
Ambeed A121900 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline 95+% 25g $235 2021-12-16 Buy
American Custom Chemicals Corporation API0024668 ERLOTINIB 95.00% 100MG $179.55 2021-12-16 Buy
American Custom Chemicals Corporation API0024668 ERLOTINIB 95.00% 500MG $701.2 2021-12-16 Buy
American Custom Chemicals Corporation API0024668 ERLOTINIB 95.00% 1G $752.14 2021-12-16 Buy
American Custom Chemicals Corporation API0024668 ERLOTINIB 95.00% 5G $1325.59 2021-12-16 Buy
ApexBio Technology A3397 Erlotinib 1g $50 2021-12-16 Buy
ApexBio Technology A3397 Erlotinib 10mM(in 1mL DMSO) $55 2021-12-16 Buy

Properties

Melting point :159-160 °C
Boiling point :553.6±50.0 °C(Predicted)
Density :1.24
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :5.32±0.30(Predicted)
color :White
CAS DataBase Reference :183321-74-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
H304 May be fatal if swallowed and enters airways Aspiration hazard Category 1 Danger GHS hazard pictograms
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P331 Do NOT induce vomiting.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 μM). This inhibits tumor growth in human head and neck carcinoma (HN5) tumor xenografts in mice with an ED50 value of 9 mg/kg. Erlotinib also suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 μM) and JAK2 mutant JAK2V617F (IC50 = 5 μM), which is associated with polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia. The drug form of Erlotinib, Tarceva?, is used to treat certain forms of cancer, including non-small cell lung cancer.

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