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ChemicalBook >> CAS DataBase List >> Endoxifen

Endoxifen

Endoxifen price.
  • $42 - $1437.11
  • Product name: Endoxifen
  • CAS: 112093-28-4
  • MF: C25H27NO2
  • MW: 373.49
  • EINECS:
  • MDL Number:
  • Synonyms:(Z)-4-Hydroxy-N-desmethyl Tamoxifen;4-[(1Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol;Endoxifen;Phenol, 4-[(1Z)-1-[4-[2-(MethylaMino)ethoxy]phenyl]-2-phenyl-1-butenyl]-;(Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer) see D292043;(Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer) ;(Z)-4-Hydroxy-N-DesMethyl TaMoxifen (Endoxifen);(Z)-Endoxifen
20 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • ChemScene
  • Crysdot
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 0.5mg
  • 50
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50MG
  • 100mg
  • ManufacturerAK Scientific
  • Product numberX5886
  • Product descriptionN-Desmethyl-4-hydroxytamoxifen,(mixtureofisomers)
  • Packaging10mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010318
  • Product description(Z)-ENDOXIFEN 95.00%
  • Packaging10MG
  • Price$794.36
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010318
  • Product description(Z)-ENDOXIFEN 95.00%
  • Packaging50MG
  • Price$1437.11
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7481
  • Product descriptionEndoxifen
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7481
  • Product descriptionEndoxifen
  • Packaging50mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFE15969
  • Product descriptionEndoxifen
  • Packaging25mg
  • Price$620
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFE15969
  • Product descriptionEndoxifen
  • Packaging10mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFE15969
  • Product descriptionEndoxifen
  • Packaging5mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFE15969
  • Product descriptionEndoxifen
  • Packaging2mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFE15969
  • Product descriptionEndoxifen
  • Packaging1mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5082
  • Product descriptionEndoxifenZ-isomer
  • Packaging5mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5082
  • Product descriptionEndoxifenZ-isomer
  • Packaging10mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004542
  • Product descriptionEndoxifen 98+%
  • Packaging5mg
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004542
  • Product descriptionEndoxifen 98+%
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004542
  • Product descriptionEndoxifen 98+%
  • Packaging50mg
  • Price$196
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004542
  • Product descriptionEndoxifen 98+%
  • Packaging100mg
  • Price$336
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X5886 N-Desmethyl-4-hydroxytamoxifen,(mixtureofisomers) 10mg $280 2021-12-16 Buy
American Custom Chemicals Corporation API0010318 (Z)-ENDOXIFEN 95.00% 10MG $794.36 2021-12-16 Buy
American Custom Chemicals Corporation API0010318 (Z)-ENDOXIFEN 95.00% 50MG $1437.11 2021-12-16 Buy
ApexBio Technology B7481 Endoxifen 10mg $75 2021-12-16 Buy
ApexBio Technology B7481 Endoxifen 50mg $245 2021-12-16 Buy
Biosynth Carbosynth FE15969 Endoxifen 25mg $620 2021-12-16 Buy
Biosynth Carbosynth FE15969 Endoxifen 10mg $300 2021-12-16 Buy
Biosynth Carbosynth FE15969 Endoxifen 5mg $180 2021-12-16 Buy
Biosynth Carbosynth FE15969 Endoxifen 2mg $112 2021-12-16 Buy
Biosynth Carbosynth FE15969 Endoxifen 1mg $75 2021-12-16 Buy
ChemScene CS-5082 EndoxifenZ-isomer 5mg $160 2021-12-16 Buy
ChemScene CS-5082 EndoxifenZ-isomer 10mg $280 2021-12-16 Buy
Crysdot CD31004542 Endoxifen 98+% 5mg $42 2021-12-16 Buy
Crysdot CD31004542 Endoxifen 98+% 10mg $60 2021-12-16 Buy
Crysdot CD31004542 Endoxifen 98+% 50mg $196 2021-12-16 Buy
Crysdot CD31004542 Endoxifen 98+% 100mg $336 2021-12-16 Buy

Properties

Melting point :127-129°C
Boiling point :519.3±50.0 °C(Predicted)
Density :1.099±0.06 g/cm3(Predicted)
storage temp. :Amber Vial, -86°C Freezer, Under Inert Atmosphere
solubility :DMSO : 50 mg/mL (133.87 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form :Powder
pka :10.36±0.15(Predicted)
color :White to off-white
Stability :Light Sensitive, Temperature Sensitive

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.

Description

Tamoxifen (TMX; ) is a selective estrogen receptor (ER) modulator used as adjuvant therapy for estrogen-dependent breast cancer. Endoxifen is an active metabolite of TMX, produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-fold greater affinity for ERs than TMX. As the efficient conversion of TMX to endoxifen depends on CYP2D6, polymorphisms in this CYP isoform can impact the effectiveness of TMX treatment.