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ChemicalBook >> CAS DataBase List >> Afimoxifene

Afimoxifene

Afimoxifene price.
  • $32 - $2523
  • Product name: Afimoxifene
  • CAS: 68392-35-8
  • MF: C26H29NO2
  • MW: 387.51
  • EINECS:
  • MDL Number:
  • Synonyms:AFIMOXIFENE;4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol;4-Hydroxytamoxifen, (E)-isomer;4-Hydroxytamoxifen, (Z)-isomer;4-Monohydroxytamoxifen;4-Oht hydrotamoxifen;C016601;(E/Z)-4-Hydroxy Tamoxifen
22 prices
Selected condition：
Brand
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 5MG
  • 10mg
  • 25mg
  • 50MG
  • 100mg
  • 250mg
  • 1ml
  • 1g
  • ManufacturerAmbeed
  • Product numberA982086
  • Product descriptionAfimoxifene 98%
  • Packaging100mg
  • Price$421
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA982086
  • Product descriptionAfimoxifene 98%
  • Packaging250mg
  • Price$841
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA982086
  • Product descriptionAfimoxifene 98%
  • Packaging1g
  • Price$2523
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005112
  • Product descriptionAFIMOXIFENE 95.00%
  • Packaging5MG
  • Price$284.9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005112
  • Product descriptionAFIMOXIFENE 95.00%
  • Packaging50MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6167
  • Product description4-Hydroxytamoxifen
  • Packaging10mg
  • Price$82
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6167
  • Product description4-Hydroxytamoxifen
  • Packaging50mg
  • Price$348
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17308
  • Product description(E/Z)-4-hydroxy Tamoxifen ≥98% (E) and (Z) isomers (50:50)
  • Packaging5mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17308
  • Product description(E/Z)-4-hydroxy Tamoxifen ≥98% (E) and (Z) isomers (50:50)
  • Packaging10mg
  • Price$61
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17308
  • Product description(E/Z)-4-hydroxy Tamoxifen ≥98% (E) and (Z) isomers (50:50)
  • Packaging25mg
  • Price$131
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17308
  • Product description(E/Z)-4-hydroxy Tamoxifen ≥98% (E) and (Z) isomers (50:50)
  • Packaging50mg
  • Price$230
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10832
  • Product description(E/Z)-4-hydroxyTamoxifen >98%
  • Packaging100mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10832
  • Product description(E/Z)-4-hydroxyTamoxifen >98%
  • Packaging250mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10832
  • Product description(E/Z)-4-hydroxyTamoxifen >98%
  • Packaging1g
  • Price$1450
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number46779
  • Product description(E/Z)-4-HydroxyTamoxifen
  • Packaging5mg
  • Price$640
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberT176
  • Product description4-Hydroxytamoxifen analytical standard, (
  • Packaging10mg
  • Price$88.8
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A982086 Afimoxifene 98% 100mg $421 2021-12-16 Buy
Ambeed A982086 Afimoxifene 98% 250mg $841 2021-12-16 Buy
Ambeed A982086 Afimoxifene 98% 1g $2523 2021-12-16 Buy
American Custom Chemicals Corporation API0005112 AFIMOXIFENE 95.00% 5MG $284.9 2021-12-16 Buy
American Custom Chemicals Corporation API0005112 AFIMOXIFENE 95.00% 50MG $1871.1 2021-12-16 Buy
ApexBio Technology B6167 4-Hydroxytamoxifen 10mg $82 2021-12-16 Buy
ApexBio Technology B6167 4-Hydroxytamoxifen 50mg $348 2021-12-16 Buy
Cayman Chemical 17308 (E/Z)-4-hydroxy Tamoxifen ≥98% (E) and (Z) isomers (50:50) 5mg $32 2024-03-01 Buy
Cayman Chemical 17308 (E/Z)-4-hydroxy Tamoxifen ≥98% (E) and (Z) isomers (50:50) 10mg $61 2024-03-01 Buy
Cayman Chemical 17308 (E/Z)-4-hydroxy Tamoxifen ≥98% (E) and (Z) isomers (50:50) 25mg $131 2024-03-01 Buy
Cayman Chemical 17308 (E/Z)-4-hydroxy Tamoxifen ≥98% (E) and (Z) isomers (50:50) 50mg $230 2024-03-01 Buy
DC Chemicals DC10832 (E/Z)-4-hydroxyTamoxifen >98% 100mg $350 2021-12-16 Buy
DC Chemicals DC10832 (E/Z)-4-hydroxyTamoxifen >98% 250mg $700 2021-12-16 Buy
DC Chemicals DC10832 (E/Z)-4-hydroxyTamoxifen >98% 1g $1450 2021-12-16 Buy
Medical Isotopes, Inc. 46779 (E/Z)-4-HydroxyTamoxifen 5mg $640 2021-12-16 Buy
Sigma-Aldrich T176 4-Hydroxytamoxifen analytical standard, ( 10mg $88.8 2024-03-01 Buy

Properties

Melting point :135-144°C
Boiling point :514.4±50.0 °C(Predicted)
Density :1.092
storage temp. :2-8°C
solubility :methanol: soluble10mg/mL
form :solution
pka :9.38±0.15(Predicted)
color :white to off-white

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Tamoxifen is a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer. Although it is an antagonist of ER action in breast tissue, it acts as an ER agonist in bone and blood vessels and a partial ER agonist in uterine tissues. ?(E/Z)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen that is formed by the action of cytochrome P450 2D6 in human liver. It exhibits more potent estrogen agonist/antagonist activity than its parent compound and can inhibit MCF-7 and MDA-MB-231 cell proliferation with IC50 values of 27 and 18 μM, respectively. ?(E/Z)-4-hydroxy Tamoxifen has been used to stimulate LC3 lipidation and formation of autophagic vesicles in a superoxide-dependent manner.

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