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ChemicalBook >> CAS DataBase List >> Endosidin 2

Endosidin 2

Endosidin 2 price.
  • $65 - $424
  • Product name: Endosidin 2
  • CAS: 1839524-44-5
  • MF: C15H12FIN2O3
  • MW: 414.17
  • EINECS:
  • MDL Number:
  • Synonyms:Endosidin 2;Endosidin-2 (ES-2);Benzoic acid, 3-fluoro-, (2E)-2-[(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]hydrazide;3-fluoro-benzoicacid,(2E)-2-[(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]hydrazide;(E)-3-Fluoro-N'-(4-hydroxy-3-iodo-5-methoxybenzylidene)benzohydrazide;3-fluoro-N'-[(E)-(4-hydroxy-3-iodo-5-methoxyphenyl)methylidene]benzohydrazide
5 prices
Selected condition:
Brand
  • Cayman Chemical
  • Sigma-Aldrich
Package
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerCayman Chemical
  • Product number21888
  • Product descriptionEndosidin 2 ≥98%
  • Packaging5mg
  • Price$65
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21888
  • Product descriptionEndosidin 2 ≥98%
  • Packaging10mg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21888
  • Product descriptionEndosidin 2 ≥98%
  • Packaging25mg
  • Price$254
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML1681
  • Product descriptionEndosidin2 ≥98% (HPLC)
  • Packaging5MG
  • Price$105
  • Updated2023-06-20
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML1681
  • Product descriptionEndosidin2 ≥98% (HPLC)
  • Packaging25MG
  • Price$424
  • Updated2023-06-20
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 21888 Endosidin 2 ≥98% 5mg $65 2024-03-01 Buy
Cayman Chemical 21888 Endosidin 2 ≥98% 10mg $121 2024-03-01 Buy
Cayman Chemical 21888 Endosidin 2 ≥98% 25mg $254 2024-03-01 Buy
Sigma-Aldrich SML1681 Endosidin2 ≥98% (HPLC) 5MG $105 2023-06-20 Buy
Sigma-Aldrich SML1681 Endosidin2 ≥98% (HPLC) 25MG $424 2023-06-20 Buy

Properties

Density :1.67±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (greater than 40 mg/ml), in DMF (up to 35 mg/ml) or in Ethanol (up to 10 mg/ml)
form :powder
pka :7.75±0.36(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO, DMF or ethanol may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Endosidin-2 (1839524-44-5) binds to the EXO70 subunit of the exocyst complex which results in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking. EXO70 is a component of the octameric exocyst complex which tethers post-Golgi vesicles to the plasma membrane before SNARE- mediated membrane fusion.2?Endosidin-2 was previously identified as a plant endomembrane trafficking disruptor.3?Inhibits intracellular glucose transporter, GLUT4 trafficking to the membrane and impairs glucose uptake in response to insulin.4?It is a valuable new tool for the study of exocytosis.

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