N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-aMine
- $55 - $5372
- Product name: N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-aMine
- CAS: 662163-81-7
- MF: C20H22N4
- MW: 318.42
- EINECS:
- MDL Number:MFCD04077630
- Synonyms:N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-aMine;Importazole;CS-2426;ImportazoL;4-Quinazolinamine, N-(1-phenylethyl)-2-(1-pyrrolidinyl)-;Apoptosis,Importazole,Inhibitor,inhibit
18 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number4806CJ
- Product descriptionImportazole
- Packaging250mg
- Price$330
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA528010
- Product descriptionImportazole 98+%
- Packaging5mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA528010
- Product descriptionImportazole 98+%
- Packaging10mg
- Price$93
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA528010
- Product descriptionImportazole 98+%
- Packaging25mg
- Price$158
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA528010
- Product descriptionImportazole 98+%
- Packaging1g
- Price$5372
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS586679
- Product descriptionImportazole ≥98%
- Packaging25mg
- Price$156
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545897
- Product descriptionImportazole >98%
- Packaging5mg
- Price$154.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545897
- Product descriptionImportazole >98%
- Packaging25mg
- Price$389.3
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21491
- Product descriptionImportazole ≥98%
- Packaging5mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21491
- Product descriptionImportazole ≥98%
- Packaging10mg
- Price$115
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21491
- Product descriptionImportazole ≥98%
- Packaging25mg
- Price$239
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21491
- Product descriptionImportazole ≥98%
- Packaging50mg
- Price$448
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC10027
- Product descriptionImportazole >98%
- Packaging100mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10027
- Product descriptionImportazole >98%
- Packaging1g
- Price$1400
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0341
- Product descriptionImportazole ≥98% (HPLC)
- Packaging5mg
- Price$127
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0341
- Product descriptionImportazole ≥98% (HPLC)
- Packaging25mg
- Price$505
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 4806CJ | Importazole | 250mg | $330 | 2021-12-16 | Buy |
Ambeed | A528010 | Importazole 98+% | 5mg | $55 | 2021-12-16 | Buy |
Ambeed | A528010 | Importazole 98+% | 10mg | $93 | 2021-12-16 | Buy |
Ambeed | A528010 | Importazole 98+% | 25mg | $158 | 2021-12-16 | Buy |
Ambeed | A528010 | Importazole 98+% | 1g | $5372 | 2021-12-16 | Buy |
Arctom | AS586679 | Importazole ≥98% | 25mg | $156 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545897 | Importazole >98% | 5mg | $154.7 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545897 | Importazole >98% | 25mg | $389.3 | 2021-12-16 | Buy |
Cayman Chemical | 21491 | Importazole ≥98% | 5mg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 21491 | Importazole ≥98% | 10mg | $115 | 2024-03-01 | Buy |
Cayman Chemical | 21491 | Importazole ≥98% | 25mg | $239 | 2024-03-01 | Buy |
Cayman Chemical | 21491 | Importazole ≥98% | 50mg | $448 | 2024-03-01 | Buy |
DC Chemicals | DC10027 | Importazole >98% | 100mg | $400 | 2021-12-16 | Buy |
DC Chemicals | DC10027 | Importazole >98% | 1g | $1400 | 2021-12-16 | Buy |
Sigma-Aldrich | SML0341 | Importazole ≥98% (HPLC) | 5mg | $127 | 2024-03-01 | Buy |
Sigma-Aldrich | SML0341 | Importazole ≥98% (HPLC) | 25mg | $505 | 2024-03-01 | Buy |
Properties
Boiling point :516.8±42.0 °C(Predicted)
Density :1?+-.0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >5mg/mL
pka :7.27±0.59(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Density :1?+-.0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >5mg/mL
pka :7.27±0.59(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
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Description
Importazole is a cell-permeable inhibitor of importin-β, which transports cargo molecules bearing a nuclear localization signal into the nucleus. Importazole prevents nuclear import of GFP-tagged nuclear factor of activated T cells (NFAT-GFP) in HEK293 cells (IC50 = 15 μM), which is reversible upon importazole washout. Importazole does not interfere with transportin-mediated nuclear import or chromosomal maintenance 1 (CRM1)-mediated nuclear export. Importazole inhibits nuclear import of topoisomerase IIβ binding protein 1 (TopBP1) in Xenopus egg extracts and of NF-κB in multiple myeloma cells. It also induces defects in spindle and microtubule formation in vitro.Related product price
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