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ChemicalBook >> CAS DataBase List >> N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-aMine

N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-aMine

N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-aMine price.
  • $55 - $5372
  • Product name: N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-aMine
  • CAS: 662163-81-7
  • MF: C20H22N4
  • MW: 318.42
  • EINECS:
  • MDL Number:MFCD04077630
  • Synonyms:N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-aMine;Importazole;CS-2426;ImportazoL;4-Quinazolinamine, N-(1-phenylethyl)-2-(1-pyrrolidinyl)-;Apoptosis,Importazole,Inhibitor,inhibit
18 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number4806CJ
  • Product descriptionImportazole
  • Packaging250mg
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA528010
  • Product descriptionImportazole 98+%
  • Packaging5mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA528010
  • Product descriptionImportazole 98+%
  • Packaging10mg
  • Price$93
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA528010
  • Product descriptionImportazole 98+%
  • Packaging25mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA528010
  • Product descriptionImportazole 98+%
  • Packaging1g
  • Price$5372
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS586679
  • Product descriptionImportazole ≥98%
  • Packaging25mg
  • Price$156
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545897
  • Product descriptionImportazole >98%
  • Packaging5mg
  • Price$154.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545897
  • Product descriptionImportazole >98%
  • Packaging25mg
  • Price$389.3
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21491
  • Product descriptionImportazole ≥98%
  • Packaging5mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21491
  • Product descriptionImportazole ≥98%
  • Packaging10mg
  • Price$115
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21491
  • Product descriptionImportazole ≥98%
  • Packaging25mg
  • Price$239
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21491
  • Product descriptionImportazole ≥98%
  • Packaging50mg
  • Price$448
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10027
  • Product descriptionImportazole >98%
  • Packaging100mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10027
  • Product descriptionImportazole >98%
  • Packaging1g
  • Price$1400
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0341
  • Product descriptionImportazole ≥98% (HPLC)
  • Packaging5mg
  • Price$127
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0341
  • Product descriptionImportazole ≥98% (HPLC)
  • Packaging25mg
  • Price$505
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4806CJ Importazole 250mg $330 2021-12-16 Buy
Ambeed A528010 Importazole 98+% 5mg $55 2021-12-16 Buy
Ambeed A528010 Importazole 98+% 10mg $93 2021-12-16 Buy
Ambeed A528010 Importazole 98+% 25mg $158 2021-12-16 Buy
Ambeed A528010 Importazole 98+% 1g $5372 2021-12-16 Buy
Arctom AS586679 Importazole ≥98% 25mg $156 2021-12-16 Buy
Biorbyt Ltd orb545897 Importazole >98% 5mg $154.7 2021-12-16 Buy
Biorbyt Ltd orb545897 Importazole >98% 25mg $389.3 2021-12-16 Buy
Cayman Chemical 21491 Importazole ≥98% 5mg $62 2024-03-01 Buy
Cayman Chemical 21491 Importazole ≥98% 10mg $115 2024-03-01 Buy
Cayman Chemical 21491 Importazole ≥98% 25mg $239 2024-03-01 Buy
Cayman Chemical 21491 Importazole ≥98% 50mg $448 2024-03-01 Buy
DC Chemicals DC10027 Importazole >98% 100mg $400 2021-12-16 Buy
DC Chemicals DC10027 Importazole >98% 1g $1400 2021-12-16 Buy
Sigma-Aldrich SML0341 Importazole ≥98% (HPLC) 5mg $127 2024-03-01 Buy
Sigma-Aldrich SML0341 Importazole ≥98% (HPLC) 25mg $505 2024-03-01 Buy

Properties

Boiling point :516.8±42.0 °C(Predicted)
Density :1?+-.0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >5mg/mL
pka :7.27±0.59(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Importazole is a cell-permeable inhibitor of importin-β, which transports cargo molecules bearing a nuclear localization signal into the nucleus. Importazole prevents nuclear import of GFP-tagged nuclear factor of activated T cells (NFAT-GFP) in HEK293 cells (IC50 = 15 μM), which is reversible upon importazole washout. Importazole does not interfere with transportin-mediated nuclear import or chromosomal maintenance 1 (CRM1)-mediated nuclear export. Importazole inhibits nuclear import of topoisomerase IIβ binding protein 1 (TopBP1) in Xenopus egg extracts and of NF-κB in multiple myeloma cells. It also induces defects in spindle and microtubule formation in vitro.

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