EHT1864
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- $32 - $1423
- Product name: EHT1864
- CAS: 754240-09-0
- MF: C25H27F3N2O4S2HCl
- MW: 0
- EINECS:
- MDL Number:MFCD11114384
- Synonyms:5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride;EHT 1864;2-(4-morpholinylmethyl)-5-[[5-[[7-(trifluoromethyl)-4-quinolinyl]thio]pentyl]oxy]-4H-pyran-4-one,hydrochloride (1:2);EHT 1864, >=98%;2-(morpholin-4-ylmethyl)-5-[5-[7-(trifluoromethyl)quinolin-4-yl]sulfanylpentoxy]pyran-4-one,dihydrochloride;CS-1239;CS-1343;EHT-1864;EHT-1864
23 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 250mg
- 100mg
- 50
- 10mM(in 1mL DMSO)
- 1mg
- 5mg
- 10mg
- 50mg
- ManufacturerAK Scientific
- Product number2391AH
- Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride
- Packaging1mg
- Price$82
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA638191
- Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+%
- Packaging50mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA638191
- Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+%
- Packaging10mg
- Price$117
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA638191
- Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+%
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000998
- Product descriptionEHT 1864 95.00%
- Packaging10MG
- Price$745.85
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000998
- Product descriptionEHT 1864 95.00%
- Packaging50MG
- Price$1417.71
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5487
- Product descriptionEHT 1864
- Packaging10mM(in 1mL DMSO)
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE103242
- Product descriptionEHT 1864
- Packaging10mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE103242
- Product descriptionEHT 1864
- Packaging50mg
- Price$472.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17258
- Product descriptionEHT 1864 ≥98%
- Packaging50mg
- Price$911
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17258
- Product descriptionEHT 1864 ≥98%
- Packaging10mg
- Price$214
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17258
- Product descriptionEHT 1864 ≥98%
- Packaging5mg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17258
- Product descriptionEHT 1864 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-3154
- Product descriptionEHT 1864 99.85%
- Packaging5mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3154
- Product descriptionEHT 1864 99.85%
- Packaging10mg
- Price$156
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3154
- Product descriptionEHT 1864 99.85%
- Packaging50mg
- Price$720
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2391AH | 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride | 1mg | $82 | 2021-12-16 | Buy |
| Ambeed | A638191 | 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+% | 50mg | $198 | 2021-12-16 | Buy |
| Ambeed | A638191 | 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+% | 10mg | $117 | 2021-12-16 | Buy |
| Ambeed | A638191 | 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+% | 5mg | $90 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000998 | EHT 1864 95.00% | 10MG | $745.85 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000998 | EHT 1864 95.00% | 50MG | $1417.71 | 2021-12-16 | Buy |
| ApexBio Technology | B5487 | EHT 1864 | 10mM(in 1mL DMSO) | $115 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE103242 | EHT 1864 | 10mg | $135 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE103242 | EHT 1864 | 50mg | $472.5 | 2021-12-16 | Buy |
| Cayman Chemical | 17258 | EHT 1864 ≥98% | 50mg | $911 | 2024-03-01 | Buy |
| Cayman Chemical | 17258 | EHT 1864 ≥98% | 10mg | $214 | 2024-03-01 | Buy |
| Cayman Chemical | 17258 | EHT 1864 ≥98% | 5mg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 17258 | EHT 1864 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| ChemScene | CS-3154 | EHT 1864 99.85% | 5mg | $108 | 2021-12-16 | Buy |
| ChemScene | CS-3154 | EHT 1864 99.85% | 10mg | $156 | 2021-12-16 | Buy |
| ChemScene | CS-3154 | EHT 1864 99.85% | 50mg | $720 | 2021-12-16 | Buy |
Properties
Melting point :>195°C (dec.)
storage temp. :2-8°C
solubility :H2O: soluble10mg/mL, clear
form :powder
color :white to beige
CAS DataBase Reference :754240-09-0
storage temp. :2-8°C
solubility :H2O: soluble10mg/mL, clear
form :powder
color :white to beige
CAS DataBase Reference :754240-09-0
Safety Information
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Description
EHT 1864 is an inhibitor of the Rac subfamily of Rho GTPases, that binds to Rac1, Rac1b, Rac2, and Rac3 with Kd values of 40, 50, 50, and 250 nM, respectively. It can reverse transformation of NIH 3T3 fibroblasts caused by constitutively activated Rac1, as well as Rac-dependent transformation caused by Tiam1 or Ras. EHT 1864 inhibits APP processing by γ-secretase, reducing Αβ40 and Αβ42 accumulation. It blocks breast cancer cell invasion in a collagen matrix assay and, at 10 μM, increases the size but decreases the density of dendritic spines of hippocampal neurons in culture.More related product prices
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