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ChemicalBook >> CAS DataBase List >> Doxofylline

Doxofylline

Doxofylline price.
  • $32 - $970
  • Product name: Doxofylline
  • CAS: 69975-86-6
  • MF: C11H14N4O4
  • MW: 266.25
  • EINECS:274-239-6
  • MDL Number:MFCD00865218
  • Synonyms:DOXOFYLLINE;2-(7’-teofillinmetil)-1,3-diossolano ;Doxofyliine;7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethyl-purine-2,6-dione;DOXOFYLLINE [7-(1,3-DIOXOLAN-2-YLMETHYL)-3,7-DIHYDRO-1,3-DIMETHYL-1H-PURINE-2,6-DIONE];MAXIVENT;Ansirnar;Doxof3rlline
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  • ManufacturerAHH
  • Product numberMT-50720
  • Product descriptionDoxofylline 98%
  • Packaging25g
  • Price$530
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH488
  • Product descriptionDoxofylline
  • Packaging25g
  • Price$576
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberJ60575
  • Product descriptionDoxofylline
  • Packaging5g
  • Price$129.65
  • Updated2024-03-01
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  • ManufacturerAvaChem
  • Product number1651
  • Product descriptionDoxofylline
  • Packaging100mg
  • Price$49
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number1651
  • Product descriptionDoxofylline
  • Packaging1g
  • Price$169
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberBD164389
  • Product descriptionDoxofylline
  • Packaging100mg
  • Price$50
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFD65012
  • Product descriptionDoxofylline
  • Packaging10g
  • Price$95
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFD65012
  • Product descriptionDoxofylline
  • Packaging25g
  • Price$220
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFD65012
  • Product descriptionDoxofylline
  • Packaging50g
  • Price$395
  • Updated2021-12-16
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  • ManufacturerCayman Chemical
  • Product number18746
  • Product descriptionDoxofylline ≥98%
  • Packaging1g
  • Price$32
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number18746
  • Product descriptionDoxofylline ≥98%
  • Packaging5g
  • Price$139
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number18746
  • Product descriptionDoxofylline ≥98%
  • Packaging10g
  • Price$243
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number18746
  • Product descriptionDoxofylline ≥98%
  • Packaging25g
  • Price$381
  • Updated2024-03-01
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  • ManufacturerChemenu
  • Product numberCM254614
  • Product description7-((1,3-Dioxolan-2-yl)methyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione 95%
  • Packaging100g
  • Price$153
  • Updated2021-12-16
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  • ManufacturerChemenu
  • Product numberCM254614
  • Product description7-((1,3-Dioxolan-2-yl)methyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione 95%
  • Packaging500g
  • Price$449
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number32544
  • Product descriptionDoxofylline,98%(HPLC,AT) 98%(HPLC,AT)
  • Packaging1G
  • Price$33.6
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-50720 Doxofylline 98% 25g $530 2021-12-16 Buy
AK Scientific H488 Doxofylline 25g $576 2021-12-16 Buy
Alfa Aesar J60575 Doxofylline 5g $129.65 2024-03-01 Buy
AvaChem 1651 Doxofylline 100mg $49 2021-12-16 Buy
AvaChem 1651 Doxofylline 1g $169 2021-12-16 Buy
Biosynth Carbosynth BD164389 Doxofylline 100mg $50 2021-12-16 Buy
Biosynth Carbosynth FD65012 Doxofylline 10g $95 2021-12-16 Buy
Biosynth Carbosynth FD65012 Doxofylline 25g $220 2021-12-16 Buy
Biosynth Carbosynth FD65012 Doxofylline 50g $395 2021-12-16 Buy
Cayman Chemical 18746 Doxofylline ≥98% 1g $32 2024-03-01 Buy
Cayman Chemical 18746 Doxofylline ≥98% 5g $139 2024-03-01 Buy
Cayman Chemical 18746 Doxofylline ≥98% 10g $243 2024-03-01 Buy
Cayman Chemical 18746 Doxofylline ≥98% 25g $381 2024-03-01 Buy
Chemenu CM254614 7-((1,3-Dioxolan-2-yl)methyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione 95% 100g $153 2021-12-16 Buy
Chemenu CM254614 7-((1,3-Dioxolan-2-yl)methyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione 95% 500g $449 2021-12-16 Buy
Chem-Impex 32544 Doxofylline,98%(HPLC,AT) 98%(HPLC,AT) 1G $33.6 2021-12-16 Buy

Properties

Melting point :144-146°C
Boiling point :409.46°C (rough estimate)
Density :1.2896 (rough estimate)
refractive index :1.6000 (estimate)
RTECS :XH5135000
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :0.42±0.70(Predicted)
color :White to Off-White
Water Solubility :Soluble
Merck :14,3438
InChI :InChI=1S/C11H14N4O4/c1-13-9-8(10(16)14(2)11(13)17)15(6-12-9)5-7-18-3-4-19-7/h6-7H,3-5H2,1-2H3
InChIKey :HWXIGFIVGWUZAO-UHFFFAOYSA-N
SMILES :N1(CC2OCCO2)C2=C(N(C)C(=O)N(C)C2=O)N=C1
CAS DataBase Reference :69975-86-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Doxofylline is a methylxanthine bronchodilator that has been examined in clinical trials involving patients with either bronchial asthma or chronic obstructive pulmonary disease. Its mechanism of action is related to its ability to inhibit phosphodiesterase activity and, thus, increase cAMP. Compared to other xanthine derivatives, which have direct arrhythmogenic effects, doxofylline demonstrates decreased affinity towards adenosine A1 and A2 receptors, does not interfere with calcium influx into cells, and does not antagonize the action of calcium-channel blockers.

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