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ChemicalBook >> CAS DataBase List >> Diacerein

Diacerein

Diacerein price.
  • $5 - $1732.5
  • Product name: Diacerein
  • CAS: 13739-02-1
  • MF: C19H12O8
  • MW: 368.29
  • EINECS:237-310-2
  • MDL Number:MFCD00468030
  • Synonyms:1,8-DIACETOXY-3-CARBOXYANTHRAQUINONE;DIACEREIN;DIACERHEIN;DIACETYL RHEIN;9,10-dihydro-4,5-diacetoxy-9,10-2-anthracenecarboxylicacid ;9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroicaciddiacetate ;9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroicacidiacetate ;artrodar
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  • AHH
  • AK Scientific
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  • 100g
  • 1kg
  • ManufacturerAHH
  • Product numberMT-49909
  • Product descriptionDiacerein 95%
  • Packaging0.5g
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10792
  • Product descriptionDiacerein
  • Packaging25mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10792
  • Product descriptionDiacerein
  • Packaging250mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63775
  • Product descriptionDiacerein
  • Packaging5g
  • Price$434.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63775
  • Product descriptionDiacerein
  • Packaging1g
  • Price$167.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA216806
  • Product descriptionDiacerein 98+%
  • Packaging10mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA216806
  • Product descriptionDiacerein 98+%
  • Packaging50mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA216806
  • Product descriptionDiacerein 98+%
  • Packaging100mg
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA216806
  • Product descriptionDiacerein 98+%
  • Packaging250mg
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA216806
  • Product descriptionDiacerein 98+%
  • Packaging1g
  • Price$33
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA216806
  • Product descriptionDiacerein 98+%
  • Packaging5g
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA216806
  • Product descriptionDiacerein 98+%
  • Packaging10g
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA216806
  • Product descriptionDiacerein 98+%
  • Packaging25g
  • Price$399
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA216806
  • Product descriptionDiacerein 98+%
  • Packaging100g
  • Price$1288
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024493
  • Product descriptionDIACEREIN 95.00%
  • Packaging1G
  • Price$1732.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024493
  • Product descriptionDIACEREIN 95.00%
  • Packaging100MG
  • Price$721.88
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-49909 Diacerein 95% 0.5g $350 2021-12-16 Buy
AK Scientific J10792 Diacerein 25mg $39 2021-12-16 Buy
AK Scientific J10792 Diacerein 250mg $245 2021-12-16 Buy
Alfa Aesar J63775 Diacerein 5g $434.65 2024-03-01 Buy
Alfa Aesar J63775 Diacerein 1g $167.65 2024-03-01 Buy
Ambeed A216806 Diacerein 98+% 10mg $5 2021-12-16 Buy
Ambeed A216806 Diacerein 98+% 50mg $8 2021-12-16 Buy
Ambeed A216806 Diacerein 98+% 100mg $10 2021-12-16 Buy
Ambeed A216806 Diacerein 98+% 250mg $12 2021-12-16 Buy
Ambeed A216806 Diacerein 98+% 1g $33 2021-12-16 Buy
Ambeed A216806 Diacerein 98+% 5g $105 2021-12-16 Buy
Ambeed A216806 Diacerein 98+% 10g $198 2021-12-16 Buy
Ambeed A216806 Diacerein 98+% 25g $399 2021-12-16 Buy
Ambeed A216806 Diacerein 98+% 100g $1288 2021-12-16 Buy
American Custom Chemicals Corporation API0024493 DIACEREIN 95.00% 1G $1732.5 2021-12-16 Buy
American Custom Chemicals Corporation API0024493 DIACEREIN 95.00% 100MG $721.88 2021-12-16 Buy

Properties

Melting point :217-2180C
Boiling point :631.5±55.0 °C(Predicted)
Density :1.491±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO (Sparingly), Methanol (Slightly)
pka :3.01±0.20(Predicted)
form :Solid
color :Light Yellow to Yellow
Water Solubility :240μg/L at 25℃
Merck :14,2960
InChIKey :TYNLGDBUJLVSMA-UHFFFAOYSA-N
LogP :3.126 (est)
CAS DataBase Reference :13739-02-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Diacerein is a diacetyl precursor of rhein, an anthraquinone found in plants. Rhein, at 10 μM, inhibits IL-1β signaling, suppressing signaling through NF-κB and AP-1, and reduces the expression of the matrix metalloproteases MMP-1 and MMP-13. Diacerein, presumably after conversion to rhein, down-regulates the expression of the IL-1β receptor on articular chondrocytes, enhances the expression of TGF-β, and increases collagen and aggrecan. It does not alter COX activity. It is mildly effective in ameliorating osteoarthritis.

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