CYT997
- $44 - $2839
- Product name: CYT997
- CAS: 917111-44-5
- MF: C24H30N6O2
- MW: 434.53
- EINECS:604-604-1
- MDL Number:MFCD18206787
- Synonyms:CYT997;N-Ethyl-N'-[2-methoxy-4-[5-methyl-4-[[(1S)-1-(3-pyridinyl)butyl]amino]-2-pyrimidinyl]phenyl]urea;CYT997 (Lexibulin);Lexibulin;1-ethyl-3-(2-methoxy-4-(5-methyl-4-((S)-1-(pyridin-3-yl)butylamino)pyrimidin-2-yl)phenyl)urea;CYT 997 N-Ethyl-N'-[2-methoxy-4-[5-methyl-4-[[(1S)-1-(3-pyridinyl)butyl]amino]-2-pyrimidinyl]phenyl]urea;N-Ethyl-N'-[2-methoxy-4-[5-methyl-4-[[(1S)-1-(3-pyridinyl)butyl]amino]-2-pyrimidinyl]phenyl]urea CYT997 (Lexibulin);Lexibulin(CYT-997)
21 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
Package
- 1MG
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberX7569
- Product descriptionLexibulin
- Packaging10mg
- Price$478
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000428
- Product descriptionCYT-997 95.00%
- Packaging1MG
- Price$148.05
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000428
- Product descriptionCYT-997 95.00%
- Packaging5MG
- Price$504.09
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1635
- Product descriptionCYT997(Lexibulin)
- Packaging5mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1635
- Product descriptionCYT997(Lexibulin)
- Packaging10mg
- Price$268
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1635
- Product descriptionCYT997(Lexibulin)
- Packaging50mg
- Price$961
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154725
- Product descriptionlexibulin (CYT997) >98%
- Packaging100mg
- Price$727.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154725
- Product descriptionlexibulin (CYT997) >98%
- Packaging250mg
- Price$1431.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154725
- Product descriptionlexibulin (CYT997) >98%
- Packaging1g
- Price$2839
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18395
- Product descriptionCYT997 ≥98%
- Packaging50mg
- Price$1148
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18395
- Product descriptionCYT997 ≥98%
- Packaging10mg
- Price$341
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18395
- Product descriptionCYT997 ≥98%
- Packaging5mg
- Price$193
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18395
- Product descriptionCYT997 ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM167884
- Product descriptionN-Ethyl-N''-[2-methoxy-4-[5-methyl-4-[[(1S)-1-(3-pyridinyl)butyl]amino]-2-pyrimidinyl]phenyl]urea 98%
- Packaging10mg
- Price$166
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM167884
- Product descriptionN-Ethyl-N''-[2-methoxy-4-[5-methyl-4-[[(1S)-1-(3-pyridinyl)butyl]amino]-2-pyrimidinyl]phenyl]urea 98%
- Packaging50mg
- Price$548
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3599
- Product descriptionLexibulin 98.08%
- Packaging5mg
- Price$114
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | X7569 | Lexibulin | 10mg | $478 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000428 | CYT-997 95.00% | 1MG | $148.05 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000428 | CYT-997 95.00% | 5MG | $504.09 | 2021-12-16 | Buy |
ApexBio Technology | B1635 | CYT997(Lexibulin) | 5mg | $150 | 2021-12-16 | Buy |
ApexBio Technology | B1635 | CYT997(Lexibulin) | 10mg | $268 | 2021-12-16 | Buy |
ApexBio Technology | B1635 | CYT997(Lexibulin) | 50mg | $961 | 2021-12-16 | Buy |
Biorbyt Ltd | orb154725 | lexibulin (CYT997) >98% | 100mg | $727.6 | 2021-12-16 | Buy |
Biorbyt Ltd | orb154725 | lexibulin (CYT997) >98% | 250mg | $1431.4 | 2021-12-16 | Buy |
Biorbyt Ltd | orb154725 | lexibulin (CYT997) >98% | 1g | $2839 | 2021-12-16 | Buy |
Cayman Chemical | 18395 | CYT997 ≥98% | 50mg | $1148 | 2024-03-01 | Buy |
Cayman Chemical | 18395 | CYT997 ≥98% | 10mg | $341 | 2024-03-01 | Buy |
Cayman Chemical | 18395 | CYT997 ≥98% | 5mg | $193 | 2024-03-01 | Buy |
Cayman Chemical | 18395 | CYT997 ≥98% | 1mg | $44 | 2024-03-01 | Buy |
Chemenu | CM167884 | N-Ethyl-N''-[2-methoxy-4-[5-methyl-4-[[(1S)-1-(3-pyridinyl)butyl]amino]-2-pyrimidinyl]phenyl]urea 98% | 10mg | $166 | 2021-12-16 | Buy |
Chemenu | CM167884 | N-Ethyl-N''-[2-methoxy-4-[5-methyl-4-[[(1S)-1-(3-pyridinyl)butyl]amino]-2-pyrimidinyl]phenyl]urea 98% | 50mg | $548 | 2021-12-16 | Buy |
ChemScene | CS-3599 | Lexibulin 98.08% | 5mg | $114 | 2021-12-16 | Buy |
Properties
Boiling point :546.9±50.0 °C(Predicted)
Density :1.195
storage temp. :Store at -20°C
solubility :DMSO:69.0(Max Conc. mg/mL);158.79(Max Conc. mM)
Ethanol:51.0(Max Conc. mg/mL);117.37(Max Conc. mM) pka :14.01±0.70(Predicted)
form :Powder
color :White to off-white
Density :1.195
storage temp. :Store at -20°C
solubility :DMSO:69.0(Max Conc. mg/mL);158.79(Max Conc. mM)
Ethanol:51.0(Max Conc. mg/mL);117.37(Max Conc. mM) pka :14.01±0.70(Predicted)
form :Powder
color :White to off-white
Safety Information
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Signal word: | Warning | |||||||
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Precautionary statements: |
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Description
CYT997 is an orally available inhibitor of microtubule polymerization (IC50 = ~3 μM) that blocks cell cycling at the G2-M phase, which leads to cell death. It is cytotoxic to a range of cancer cell lines (IC50s = 9-101 nM) and demonstrates antivascular activity in tumors both in vitro and in vivo. CYT997 is being examined in clinical trials for efficacy against advanced solid tumors.Related product price
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