CID-49830258
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- $49 - $1083
- Product name: CID-49830258
- CAS: 1346527-98-7
- MF: C23H20N6O
- MW: 396.44
- EINECS:
- MDL Number:MFCD28137687
- Synonyms:2-(2-Amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine;CID-49830258;ML240;2-(2-amino-1H-benzo[d]imidazol-1-yl)-N-benzyl-8-methoxyquinazolin-4-amine;2-(2-Amino-1H-benzimidazole-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine;CS-2775;ML240, >98%;4-Quinazolinamine, 2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-
31 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 25mg
- 50
- 10mg
- 50mg
- 100mg
- 250mg
- 500mg
- ManufacturerAK Scientific
- Product numberSYN5296
- Product descriptionML240
- Packaging50mg
- Price$634
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5296
- Product descriptionML240
- Packaging100mg
- Price$1083
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4926
- Product descriptionML240
- Packaging5mg
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4926
- Product descriptionML240
- Packaging10mg
- Price$213
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4926
- Product descriptionML240
- Packaging25mg
- Price$449
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4926
- Product descriptionML240
- Packaging50mg
- Price$764
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBM177450
- Product descriptionML 240 NEW
- Packaging25mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBM177450
- Product descriptionML 240 NEW
- Packaging50mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBM177450
- Product descriptionML 240 NEW
- Packaging100mg
- Price$370
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBM177450
- Product descriptionML 240 NEW
- Packaging250mg
- Price$625
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBM177450
- Product descriptionML 240 NEW
- Packaging500mg
- Price$850
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17373
- Product descriptionML-240 ≥95%
- Packaging1mg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17373
- Product descriptionML-240 ≥95%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17373
- Product descriptionML-240 ≥95%
- Packaging10mg
- Price$168
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17373
- Product descriptionML-240 ≥95%
- Packaging25mg
- Price$298
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5653
- Product descriptionML240 99.76%
- Packaging5mg
- Price$84
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5296 | ML240 | 50mg | $634 | 2021-12-16 | Buy |
| AK Scientific | SYN5296 | ML240 | 100mg | $1083 | 2021-12-16 | Buy |
| ApexBio Technology | B4926 | ML240 | 5mg | $132 | 2021-12-16 | Buy |
| ApexBio Technology | B4926 | ML240 | 10mg | $213 | 2021-12-16 | Buy |
| ApexBio Technology | B4926 | ML240 | 25mg | $449 | 2021-12-16 | Buy |
| ApexBio Technology | B4926 | ML240 | 50mg | $764 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BM177450 | ML 240 NEW | 25mg | $210 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BM177450 | ML 240 NEW | 50mg | $280 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BM177450 | ML 240 NEW | 100mg | $370 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BM177450 | ML 240 NEW | 250mg | $625 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BM177450 | ML 240 NEW | 500mg | $850 | 2021-12-16 | Buy |
| Cayman Chemical | 17373 | ML-240 ≥95% | 1mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 17373 | ML-240 ≥95% | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 17373 | ML-240 ≥95% | 10mg | $168 | 2024-03-01 | Buy |
| Cayman Chemical | 17373 | ML-240 ≥95% | 25mg | $298 | 2024-03-01 | Buy |
| ChemScene | CS-5653 | ML240 99.76% | 5mg | $84 | 2021-12-16 | Buy |
Properties
Boiling point :696.6±65.0 °C(Predicted)
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :powder
pka :4.53±0.10(Predicted)
color :white to yellow to light brown
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :powder
pka :4.53±0.10(Predicted)
color :white to yellow to light brown
Safety Information
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Description
The p97 AAA (ATPase associated with diverse cellular activities) uses energy from ATP hydrolysis to unfold proteins or disassemble protein complexes. p97 is a hexameric protein consisting of two AAA domains (D1 and D2) that form two stacked rings and an N-terminal domain that recruits cofactor/substrate specificity factors. It functions in many regulatory processes to maintain protein homeostasis and has become a therapeutic target for cancer and neurodegenerative diseases. ML-240 is an ATP-competitive inhibitor of the D2 domain of the p97 ATPase (IC50 = 0.11 μM; Ki = 0.22 μM). It disrupts the endoplasmic reticulum-associated degradation and autophagy pathways, preventing the degradation of p97-dependent proteasome substrates (IC50 = 0.9 μM) and causing accumulation of ubiquitin conjugates in nuclear membrane and cytosolic compartments at 5-10 μM. ML-240 has also been shown to block proliferation of HCT15 and SW403 colon cancer cell lines (GI50s = 0.76 and 0.5 μM, respectively) and to rapidly mobilize caspase-3 and -7, inducing apoptosis.More related product prices
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