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ChemicalBook >> CAS DataBase List >> CHK2 INHIBITOR II

CHK2 INHIBITOR II

CHK2 INHIBITOR II price.
  • $32 - $1500
  • Product name: CHK2 INHIBITOR II
  • CAS: 516480-79-8
  • MF: C20H14ClN3O2
  • MW: 363.8
  • EINECS:
  • MDL Number:MFCD08276917
  • Synonyms:C 3742;BML-277;2-(4-(4-CHLOROPHENOXY)PHENYL)-1H-BENZO[D]IMIDAZOLE-5-CARBOXAMIDE;2-[4-(4-Chlorophenoxy)phenyl]-1H-benzimidazole-5-carboxylic acid amide;C 3742 BML-277;InSolution? Chk2 Inhibitor II ;2-[4-(4-chlorophenoxy)phenyl]-1H-benzimidazole-6-carboxamide;2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide hydrate
22 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAK Scientific
  • Product number3100AH
  • Product description2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamidehydrate
  • Packaging1mg
  • Price$92
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3100AH
  • Product description2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamidehydrate
  • Packaging100mg
  • Price$281
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000174
  • Product descriptionBML-277 95.00%
  • Packaging1MG
  • Price$409
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000174
  • Product descriptionBML-277 95.00%
  • Packaging25MG
  • Price$547
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1236
  • Product descriptionBML-277
  • Packaging10mg
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1236
  • Product descriptionBML-277
  • Packaging10mM(in 1mL DMSO)
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1236
  • Product descriptionBML-277
  • Packaging50mg
  • Price$304
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545802
  • Product descriptionbML-277 >98%
  • Packaging10mg
  • Price$226.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545802
  • Product descriptionbML-277 >98%
  • Packaging50mg
  • Price$654.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17552
  • Product descriptionChk2 Inhibitor II ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17552
  • Product descriptionChk2 Inhibitor II ≥98%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17552
  • Product descriptionChk2 Inhibitor II ≥98%
  • Packaging10mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM161164
  • Product description2-(4-(4-chlorophenoxy)phenyl)-1H-benzo[d]imidazole-6-carboxamide 98%
  • Packaging50mg
  • Price$287
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1809
  • Product descriptionBML-277 97.94%
  • Packaging10mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1809
  • Product descriptionBML-277 97.94%
  • Packaging50mg
  • Price$384
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001668
  • Product descriptionBML-277 98+%
  • Packaging50mg
  • Price$304
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3100AH 2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamidehydrate 1mg $92 2021-12-16 Buy
AK Scientific 3100AH 2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamidehydrate 100mg $281 2021-12-16 Buy
American Custom Chemicals Corporation INB0000174 BML-277 95.00% 1MG $409 2021-12-16 Buy
American Custom Chemicals Corporation INB0000174 BML-277 95.00% 25MG $547 2021-12-16 Buy
ApexBio Technology B1236 BML-277 10mg $76 2021-12-16 Buy
ApexBio Technology B1236 BML-277 10mM(in 1mL DMSO) $88 2021-12-16 Buy
ApexBio Technology B1236 BML-277 50mg $304 2021-12-16 Buy
Biorbyt Ltd orb545802 bML-277 >98% 10mg $226.1 2021-12-16 Buy
Biorbyt Ltd orb545802 bML-277 >98% 50mg $654.5 2021-12-16 Buy
Cayman Chemical 17552 Chk2 Inhibitor II ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 17552 Chk2 Inhibitor II ≥98% 5mg $93 2024-03-01 Buy
Cayman Chemical 17552 Chk2 Inhibitor II ≥98% 10mg $120 2024-03-01 Buy
Chemenu CM161164 2-(4-(4-chlorophenoxy)phenyl)-1H-benzo[d]imidazole-6-carboxamide 98% 50mg $287 2021-12-16 Buy
ChemScene CS-1809 BML-277 97.94% 10mg $96 2021-12-16 Buy
ChemScene CS-1809 BML-277 97.94% 50mg $384 2021-12-16 Buy
Crysdot CD31001668 BML-277 98+% 50mg $304 2021-12-16 Buy

Properties

Boiling point :637.1±63.0 °C(Predicted)
Density :1.390±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 18 mg/mL
form :solid
pka :10.40±0.10(Predicted)
color :tan
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Chk2 inhibitor II is a selective, ATP-competitive inhibitor of the DNA damage control kinase, checkpoint kinase 2 (IC50 = 15 nM). It has been shown to prevent apoptosis in human T-cells exposed to ionizing radiation (EC50 = 3-7.6 μM). This compound has been used to target the role of Chk2 in cellular signaling in response to DNA damage.

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