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ChemicalBook >> CAS DataBase List >> Brimonidine Tartrate

Brimonidine Tartrate

Brimonidine Tartrate price.
  • $5 - $3500
  • Product name: Brimonidine Tartrate
  • CAS: 70359-46-5
  • MF: C15H16BrN5O6
  • MW: 442.22
  • EINECS:629-848-5
  • MDL Number:MFCD07773072
  • Synonyms:5-BROMO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-6-QUINOXALINAMINE TARTRATE;5-BROMO-6-(2-IMIDAZOLIN-2-YLAMINO)QUINOXALINE TARTRATE;BRIMONIDINE D-TARTRATE;BRIMONIDINE TARTATE;UK 14,304 TARTRATE;Brimonidine-L-Tartrate;Brimonidinne tartrate;Brimonidine Tartrate(Alphagan)
41 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Arctom
  • AstaTech
  • AvaChem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 5mg
  • 10mg
  • 25mg
  • 10
  • 50mg
  • 100mg
  • 250mg
  • 500MG
  • 1g
  • 5g
  • y0001658
  • 0.25/ G
  • 1/ G
  • 5/ G
  • ManufacturerAK Scientific
  • Product numberJ11117
  • Product descriptionBrimonidineD-tartrate
  • Packaging5mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberG159
  • Product descriptionBrimonidineD-tartrate
  • Packaging250mg
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA139688
  • Product description5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate 98+%
  • Packaging10mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA139688
  • Product description5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate 98+%
  • Packaging50mg
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA139688
  • Product description5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate 98+%
  • Packaging100mg
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA139688
  • Product description5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate 98+%
  • Packaging250mg
  • Price$24
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA139688
  • Product description5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate 98+%
  • Packaging1g
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA139688
  • Product description5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate 98+%
  • Packaging5g
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007142
  • Product descriptionBRIMONIDINE TARTRATE 95.00%
  • Packaging100MG
  • Price$521.88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007142
  • Product descriptionBRIMONIDINE TARTRATE 95.00%
  • Packaging1G
  • Price$1532.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007142
  • Product descriptionBRIMONIDINE TARTRATE 95.00%
  • Packaging5G
  • Price$3500
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS448786
  • Product description5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate ≥98%
  • Packaging50mg
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS448786
  • Product description5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate ≥98%
  • Packaging100mg
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS448786
  • Product description5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate ≥98%
  • Packaging250mg
  • Price$24
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS448786
  • Product description5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate ≥98%
  • Packaging1g
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number21416
  • Product descriptionBRIMONIDINEL-TARTRATE 95%
  • Packaging0.25/ G
  • Price$95
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J11117 BrimonidineD-tartrate 5mg $20 2021-12-16 Buy
AK Scientific G159 BrimonidineD-tartrate 250mg $129 2021-12-16 Buy
Ambeed A139688 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate 98+% 10mg $5 2021-12-16 Buy
Ambeed A139688 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate 98+% 50mg $9 2021-12-16 Buy
Ambeed A139688 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate 98+% 100mg $16 2021-12-16 Buy
Ambeed A139688 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate 98+% 250mg $24 2021-12-16 Buy
Ambeed A139688 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate 98+% 1g $84 2021-12-16 Buy
Ambeed A139688 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate 98+% 5g $119 2021-12-16 Buy
American Custom Chemicals Corporation API0007142 BRIMONIDINE TARTRATE 95.00% 100MG $521.88 2021-12-16 Buy
American Custom Chemicals Corporation API0007142 BRIMONIDINE TARTRATE 95.00% 1G $1532.5 2021-12-16 Buy
American Custom Chemicals Corporation API0007142 BRIMONIDINE TARTRATE 95.00% 5G $3500 2021-12-16 Buy
Arctom AS448786 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate ≥98% 50mg $9 2021-12-16 Buy
Arctom AS448786 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate ≥98% 100mg $16 2021-12-16 Buy
Arctom AS448786 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate ≥98% 250mg $24 2021-12-16 Buy
Arctom AS448786 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine(2R,3R)-2,3-dihydroxysuccinate ≥98% 1g $39 2021-12-16 Buy
AstaTech 21416 BRIMONIDINEL-TARTRATE 95% 0.25/ G $95 2021-12-16 Buy

Properties

Melting point :207-208°C (dec.)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: 1 mg/ml; PBS (pH 7.2): 3 mg/ml
form :Solid
color :White to off-white
InChIKey :QZHBYNSSDLTCRG-WUUYCOTASA-N
CAS DataBase Reference :70359-46-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Brimonidine is a selective α2-adrenergic receptor agonist that lowers intraocular pressure by decreasing aqueous humor synthesis and increasing drainage through uveoscleral outflow. By stimulating α2-adrenergic receptors coupled to their G proteins (Ki = 183 nM), brimonidine inhibits adenylate cyclase activity and reduces cAMP. Furthermore, at 1 mg/kg/day brimonidine has been shown to protect rat retinal ganglion cells against glutamate excitotoxicity by inhibiting glutamate release and blocking the upregulation of NDMA receptor 1 and 2A protein expression.

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