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ChemicalBook >> CAS DataBase List >> (-)-Blebbistatin

(-)-Blebbistatin

(-)-Blebbistatin price.
  • $28 - $2500
  • Product name: (-)-Blebbistatin
  • CAS: 856925-71-8
  • MF: C18H16N2O2
  • MW: 292.33
  • EINECS:
  • MDL Number:MFCD08460907
  • Synonyms:(-)-BLEBBISTATIN;4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-phenyl-, (3aS)-;(+/-)-BLEBBISTATIN;(S)-(-)-BLEBBISTATIN;3a-Hydroxy-6-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one (-)-Blebbistatin;3a-Hydroxy-6-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one 1,2,3,3atetrahydro3ahydroxy6methyl1phenyl4Hpyrrolo[2,3b]quinolin4one;(S)-3a-Hydroxy-6-methyl-1-phenyl-3,3a-dihydro-1H-pyrrolo[2,3-b]quinolin-4(2H)-one;(-)-Blebbistatin - CAS 856925-71-8 - Calbiochem
31 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 2mg
  • 25mg
  • 10
  • 100mg
  • 1g
  • 1
  • 1mg
  • 1unit
  • 5mg
  • 10mg
  • 50mg
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number1003AH
  • Product description(-)-Blebbistatin
  • Packaging1mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA182285
  • Product description(-)-Blebbistatin 98+%
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA182285
  • Product description(-)-Blebbistatin 98+%
  • Packaging10mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA182285
  • Product description(-)-Blebbistatin 98+%
  • Packaging50mg
  • Price$365
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCBL0000345
  • Product description(-)-Blebbistatin 95.00%
  • Packaging1MG
  • Price$174.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCBL0000345
  • Product description(-)-Blebbistatin 95.00%
  • Packaging5MG
  • Price$756.25
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1387
  • Product description(-)-Blebbistatin
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1387
  • Product description(-)-Blebbistatin
  • Packaging10mM(in 1mL DMSO)
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1387
  • Product description(-)-Blebbistatin
  • Packaging10mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1387
  • Product description(-)-Blebbistatin
  • Packaging25mg
  • Price$259
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60379
  • Product description(-)-Blebbistatin ≥98%
  • Packaging10mg
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon3074
  • Product description(-)-Blebbistatin 98%
  • Packaging2mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB18839
  • Product description(S)-(-)-Blebbistatin
  • Packaging10mg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB18839
  • Product description(S)-(-)-Blebbistatin
  • Packaging50mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13013
  • Product description(-)-Blebbistatin ≥98%
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13013
  • Product description(-)-Blebbistatin ≥98%
  • Packaging5mg
  • Price$208
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1003AH (-)-Blebbistatin 1mg $225 2021-12-16 Buy
Ambeed A182285 (-)-Blebbistatin 98+% 5mg $90 2021-12-16 Buy
Ambeed A182285 (-)-Blebbistatin 98+% 10mg $144 2021-12-16 Buy
Ambeed A182285 (-)-Blebbistatin 98+% 50mg $365 2021-12-16 Buy
American Custom Chemicals Corporation CBL0000345 (-)-Blebbistatin 95.00% 1MG $174.3 2021-12-16 Buy
American Custom Chemicals Corporation CBL0000345 (-)-Blebbistatin 95.00% 5MG $756.25 2021-12-16 Buy
ApexBio Technology B1387 (-)-Blebbistatin 1unit $28 2021-12-16 Buy
ApexBio Technology B1387 (-)-Blebbistatin 10mM(in 1mL DMSO) $65 2021-12-16 Buy
ApexBio Technology B1387 (-)-Blebbistatin 10mg $119 2021-12-16 Buy
ApexBio Technology B1387 (-)-Blebbistatin 25mg $259 2021-12-16 Buy
Arctom CFN60379 (-)-Blebbistatin ≥98% 10mg $238 2021-12-16 Buy
Axon Medchem Axon3074 (-)-Blebbistatin 98% 2mg $99 2021-12-16 Buy
Biosynth Carbosynth FB18839 (S)-(-)-Blebbistatin 10mg $185 2021-12-16 Buy
Biosynth Carbosynth FB18839 (S)-(-)-Blebbistatin 50mg $700 2021-12-16 Buy
Cayman Chemical 13013 (-)-Blebbistatin ≥98% 1mg $57 2024-03-01 Buy
Cayman Chemical 13013 (-)-Blebbistatin ≥98% 5mg $208 2024-03-01 Buy

Properties

Melting point :210-212°C
Boiling point :507.3±60.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble5mg/mL
form :Yellow solid
pka :11.15±0.20(Predicted)
color :Light Yellow to Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(?)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50 = 0.5-5.0 μM), while poorly inhibiting smooth muscle myosin (IC50 = 80 μM). Through these effects, blebbistatin blocks apoptosis-related bleb formation, directed cell migration and cytokinesis in vertebrate cells. Blebbistatin is inactivated by UV light, which may be particularly important in fluorescent cell imaging applications.

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