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ChemicalBook >> CAS DataBase List >> BAF-312(SiponiMod)

BAF-312(SiponiMod)

BAF-312(SiponiMod) price.
  • $32 - $2000
  • Product name: BAF-312(SiponiMod)
  • CAS: 1230487-00-9
  • MF: C29H35F3N2O3
  • MW: 516.59
  • EINECS:
  • MDL Number:MFCD26142651
  • Synonyms:BAF-312(SiponiMod);3-Azetidinecarboxylic acid, 1-[[4-[(1E)-1-[[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]imino]ethyl]-2-ethylphenyl]methyl]-;1-(4-[1-[(E)-4-Cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl]-2-ethyl-benzyl)-azetidine-3-carboxylic acid;BAF312 (Siponimod) 1-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-ethylphenyl]methyl]azetidine-3-carboxylic acid;Siponimod [INN];CS-1753;BAF-312(SiponiMod) USP/EP/BP;Siponimod D11
22 prices
Selected condition：
Brand
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 500mg
  • 1g
  • ManufacturerApexBio Technology
  • Product numberB3225
  • Product descriptionBAF312(Siponimod)
  • Packaging5mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3225
  • Product descriptionBAF312(Siponimod)
  • Packaging25mg
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3225
  • Product descriptionBAF312(Siponimod)
  • Packaging100mg
  • Price$580
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS103613
  • Product descriptionSiponimod
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS103613
  • Product descriptionSiponimod
  • Packaging10mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS103613
  • Product descriptionSiponimod
  • Packaging25mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS103613
  • Product descriptionSiponimod
  • Packaging50mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22057
  • Product descriptionSiponimod ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22057
  • Product descriptionSiponimod ≥98%
  • Packaging5mg
  • Price$131
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22057
  • Product descriptionSiponimod ≥98%
  • Packaging10mg
  • Price$230
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22057
  • Product descriptionSiponimod ≥98%
  • Packaging25mg
  • Price$456
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM200514
  • Product description(E)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylicacid 98%
  • Packaging100mg
  • Price$523
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3876
  • Product descriptionSiponimod 99.06%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3876
  • Product descriptionSiponimod 99.06%
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3876
  • Product descriptionSiponimod 99.06%
  • Packaging50mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3876
  • Product descriptionSiponimod 99.06%
  • Packaging100mg
  • Price$360
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B3225 BAF312(Siponimod) 5mg $80 2021-12-16 Buy
ApexBio Technology B3225 BAF312(Siponimod) 25mg $230 2021-12-16 Buy
ApexBio Technology B3225 BAF312(Siponimod) 100mg $580 2021-12-16 Buy
Biosynth Carbosynth FS103613 Siponimod 5mg $50 2021-12-16 Buy
Biosynth Carbosynth FS103613 Siponimod 10mg $80 2021-12-16 Buy
Biosynth Carbosynth FS103613 Siponimod 25mg $125 2021-12-16 Buy
Biosynth Carbosynth FS103613 Siponimod 50mg $195 2021-12-16 Buy
Cayman Chemical 22057 Siponimod ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 22057 Siponimod ≥98% 5mg $131 2024-03-01 Buy
Cayman Chemical 22057 Siponimod ≥98% 10mg $230 2024-03-01 Buy
Cayman Chemical 22057 Siponimod ≥98% 25mg $456 2024-03-01 Buy
Chemenu CM200514 (E)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylicacid 98% 100mg $523 2021-12-16 Buy
ChemScene CS-3876 Siponimod 99.06% 5mg $60 2021-12-16 Buy
ChemScene CS-3876 Siponimod 99.06% 10mg $90 2021-12-16 Buy
ChemScene CS-3876 Siponimod 99.06% 50mg $260 2021-12-16 Buy
ChemScene CS-3876 Siponimod 99.06% 100mg $360 2021-12-16 Buy

Properties

Melting point :154 - 157°C
Boiling point :602.0±65.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
pka :2.69±0.20(Predicted)
form :Solid
color :White to Off-White
InChIKey :KIHYPELVXPAIDH-HNSNBQBZSA-N
SMILES :N1(CC2=CC=C(/C(=N/OCC3=CC=C(C4CCCCC4)C(C(F)(F)F)=C3)/C)C=C2CC)CC(C(O)=O)C1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

S1p signaling is important for immune, cardiovascular, and CNS function.Like its FDA approved predecessor fingolimod, siponimod is an oral S1p signaling modulator.While fin- golimod binds four out of five known S1p receptors, siponimod is selective for receptor sub- types 1 and 5. This selectivity may allow for an improved adverse event profile.