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ChemicalBook >> CAS DataBase List >> Acarbose

Acarbose

Acarbose price.
  • $6 - $2245.7
  • Product name: Acarbose
  • CAS: 56180-94-0
  • MF: C25H43NO18
  • MW: 645.61
  • EINECS:260-030-7
  • MDL Number:MFCD00869592
  • Synonyms:4)-O-a-D-glucopyranosyl-(1®D-Glucose,O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxyMethyl)-2-cyclohexen-1-yl]aMino]-a-D-glucopyranosyl-(1®Acarbose (Acarbosum);(2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-;O-4,6-Dideoxy-4-[[[1S-(1α,4α,5β,6α)]-4,5,6-trihydroxy-3-(hydroxyMethyl)-2-cyclohexen-1-yl]aMino]-α-D-glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-glucose;Acarbose API;O-4,6-DIDEOXY-4-[[[1S-(1A,4A,5BETA,6A)]-4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-2-CYCLOHEXEN-1-YL]AMINO]-ALPHA-D-GLUCOPYRANOSYL-(1-4)-O-ALPHA-D-GLUCOPYRANOSYL-(1-4)-D-GLUCOSE;5-[5-[3,4-DIHYDROXY-6-METHYL-5-[[4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-1-CYCLOHEX-2-ENYL]AMINO]OXAN-2-YL]OXY-3,4-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]OXY-6-(HYDROXYMETHYL)OXANE-2,3,4-TRIOL
54 prices
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Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
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Package
  • y0000500
  • y0000354
  • 10mM(in 1mL DMSO)
  • 20mg
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  • y0000427
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  • 50mg
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  • 1g
  • 2g
  • 5g
  • 10g
  • 25g
  • 50g
  • 100g
  • ManufacturerAHH
  • Product numberAPI-1392
  • Product descriptionAcarbose 98%
  • Packaging25g
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10300
  • Product descriptionAcarbose Hydrate
  • Packaging100mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2193AH
  • Product descriptionAcarbose
  • Packaging5g
  • Price$162
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61737
  • Product descriptionAcarbose, 95%
  • Packaging1g
  • Price$132
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61737
  • Product descriptionAcarbose, 95%
  • Packaging2g
  • Price$174.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61737
  • Product descriptionAcarbose, 95%
  • Packaging5g
  • Price$268
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA357603
  • Product description(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%
  • Packaging50mg
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA357603
  • Product description(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%
  • Packaging250mg
  • Price$17
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA357603
  • Product description(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%
  • Packaging1g
  • Price$33
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA357603
  • Product description(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%
  • Packaging5g
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA357603
  • Product description(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%
  • Packaging25g
  • Price$386
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2431
  • Product descriptionAcarbose
  • Packaging500mg
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2431
  • Product descriptionAcarbose
  • Packaging1g
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2431
  • Product descriptionAcarbose
  • Packaging10mM(in 1mL DMSO)
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2431
  • Product descriptionAcarbose
  • Packaging2g
  • Price$137
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2431
  • Product descriptionAcarbose
  • Packaging5g
  • Price$304
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1392 Acarbose 98% 25g $450 2021-12-16 Buy
AK Scientific J10300 Acarbose Hydrate 100mg $89 2021-12-16 Buy
AK Scientific 2193AH Acarbose 5g $162 2021-12-16 Buy
Alfa Aesar J61737 Acarbose, 95% 1g $132 2024-03-01 Buy
Alfa Aesar J61737 Acarbose, 95% 2g $174.65 2024-03-01 Buy
Alfa Aesar J61737 Acarbose, 95% 5g $268 2024-03-01 Buy
Ambeed A357603 (2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+% 50mg $6 2021-12-16 Buy
Ambeed A357603 (2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+% 250mg $17 2021-12-16 Buy
Ambeed A357603 (2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+% 1g $33 2021-12-16 Buy
Ambeed A357603 (2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+% 5g $111 2021-12-16 Buy
Ambeed A357603 (2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+% 25g $386 2021-12-16 Buy
ApexBio Technology A2431 Acarbose 500mg $48 2021-12-16 Buy
ApexBio Technology A2431 Acarbose 1g $76 2021-12-16 Buy
ApexBio Technology A2431 Acarbose 10mM(in 1mL DMSO) $130 2021-12-16 Buy
ApexBio Technology A2431 Acarbose 2g $137 2021-12-16 Buy
ApexBio Technology A2431 Acarbose 5g $304 2021-12-16 Buy

Properties

Melting point :165-170°C
alpha :D18 +165° (c = 0.4 in water)
Boiling point :675.05°C (rough estimate)
Density :1.4278 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :2-8°C
solubility :Very soluble in water, soluble in methanol, practically insoluble in methylene chloride.
form :Solid
pka :12.39±0.20(Predicted)
color :White to Off-White
Water Solubility :Soluble in water.
Merck :14,18
Stability :Hygroscopic
InChIKey :XUFXOAAUWZOOIT-JMPDRRIHSA-N
LogP :-7.935 (est)
CAS DataBase Reference :56180-94-0

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Acarbose is the first identified α-glucosidase inhibitor. It has been shown to delay the absorption and digestion of dietary polysaccharides by reversibly inhibiting digestive enzymes such as maltase and sucrase with IC50 values of 0.16 and 2.9 μM, respectively. It has also been shown to bind to phosphorylase kinase, potentiating its activity. In clinical trials, acarbose has been used to inhibit postprandial hyperglycemia associated with diabetes without cardiovascular complications.

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