API-2
- $47 - $2100
- Product name: API-2
- CAS: 35943-35-2
- MF: C13H16N6O4
- MW: 320.3
- EINECS:
- MDL Number:MFCD00932413
- Synonyms:API-2;6-AMINO-4-METHYL-8-(BETA-D-RIBOFURANOSYL)-4H,8H-PYRROLO[4,3,2-DE]PYRIMIDO[4,5-C]PYRIDAZINE;AKT/PKB SIGNALING INHIBITOR-2;AKT INHIBITOR V;1,5-DIHYDRO-5-METHYL-1-BETA-D-RIBOFURANOSYL-1,4,5,6,8-PENTAAZAACENAPHTHYLEN-3-AMINE;1,4,5,6,8-pentaazaacenaphthylen-3-amine,1,5-dihydro-5-methyl-1-beta-d-ribofura ;API-2 (Tricirbine);TRICIRIBINE
38 prices
Selected condition:
Brand
- AHH
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 2mg
- 10
- 10μg
- 5MG
- 0.01g
- 10mg
- 25MG
- 50mg
- 100mg
- 1g
- 400μL
- ManufacturerAHH
- Product numberMT-09744
- Product description1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8pentaazaacenaphthylen-3-amine 98%
- Packaging0.01g
- Price$415
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001275
- Product descriptionTRICIRIBINE HYDRATE 95.00%
- Packaging5MG
- Price$773.74
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001275
- Product descriptionTRICIRIBINE HYDRATE 95.00%
- Packaging25MG
- Price$1343.73
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8541
- Product descriptionTriciribine
- Packaging5mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8541
- Product descriptionTriciribine
- Packaging10mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8541
- Product descriptionTriciribine
- Packaging50mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60328
- Product descriptionTriciribine ≥98%
- Packaging10mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb530735
- Product descriptionBIRC3
- Packaging10μg
- Price$991.1
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberNT08796
- Product descriptionTriciribine
- Packaging5mg
- Price$72.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberNT08796
- Product descriptionTriciribine
- Packaging10mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberNT08796
- Product descriptionTriciribine
- Packaging25mg
- Price$237.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10010237
- Product descriptionTriciribine ≥98%
- Packaging1mg
- Price$47
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010237
- Product descriptionTriciribine ≥98%
- Packaging5mg
- Price$107
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010237
- Product descriptionTriciribine ≥98%
- Packaging10mg
- Price$161
- Updated2023-06-20
- Buy
- ManufacturerChemenu
- Product numberCM141574
- Product descriptionTriciribine 98%
- Packaging100mg
- Price$1052
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0968
- Product descriptionTriciribine 99.81%
- Packaging5mg
- Price$96
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AHH | MT-09744 | 1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8pentaazaacenaphthylen-3-amine 98% | 0.01g | $415 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0001275 | TRICIRIBINE HYDRATE 95.00% | 5MG | $773.74 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0001275 | TRICIRIBINE HYDRATE 95.00% | 25MG | $1343.73 | 2021-12-16 | Buy |
ApexBio Technology | A8541 | Triciribine | 5mg | $85 | 2021-12-16 | Buy |
ApexBio Technology | A8541 | Triciribine | 10mg | $120 | 2021-12-16 | Buy |
ApexBio Technology | A8541 | Triciribine | 50mg | $400 | 2021-12-16 | Buy |
Arctom | CFN60328 | Triciribine ≥98% | 10mg | $288 | 2021-12-16 | Buy |
Biorbyt Ltd | orb530735 | BIRC3 | 10μg | $991.1 | 2021-12-16 | Buy |
Biosynth Carbosynth | NT08796 | Triciribine | 5mg | $72.5 | 2021-12-16 | Buy |
Biosynth Carbosynth | NT08796 | Triciribine | 10mg | $125 | 2021-12-16 | Buy |
Biosynth Carbosynth | NT08796 | Triciribine | 25mg | $237.5 | 2021-12-16 | Buy |
Cayman Chemical | 10010237 | Triciribine ≥98% | 1mg | $47 | 2024-03-01 | Buy |
Cayman Chemical | 10010237 | Triciribine ≥98% | 5mg | $107 | 2024-03-01 | Buy |
Cayman Chemical | 10010237 | Triciribine ≥98% | 10mg | $161 | 2023-06-20 | Buy |
Chemenu | CM141574 | Triciribine 98% | 100mg | $1052 | 2021-12-16 | Buy |
ChemScene | CS-0968 | Triciribine 99.81% | 5mg | $96 | 2021-12-16 | Buy |
Properties
Melting point :207 °C (decomp)
Boiling point :459.21°C (rough estimate)
Density :1.2633 (rough estimate)
refractive index :1.7000 (estimate)
storage temp. :Store at RT
solubility :DMSO: >10mg/mL
form :powder
pka :12.35±0.70(Predicted)
color :tan
InChIKey :HOGVTUZUJGHKPL-HTVVRFAVSA-N
Boiling point :459.21°C (rough estimate)
Density :1.2633 (rough estimate)
refractive index :1.7000 (estimate)
storage temp. :Store at RT
solubility :DMSO: >10mg/mL
form :powder
pka :12.35±0.70(Predicted)
color :tan
InChIKey :HOGVTUZUJGHKPL-HTVVRFAVSA-N
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
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Description
Triciribine, also known as API-2, suppresses the phosphorylation level and kinase activity of Akt. Akt kinase inhibition has been shown to induce apoptosis and cell growth in cancer cell research. Triciribine can selectively inhibit Akt1, Akt2, and Akt3 without inhibiting known upstream activators,PDK1 and PI 3-Kinase, of Akt. Studies show that Triciribine in duces apoptosis and inhibits cell growth in cells that express atypical Akt1. Additionally, Triciribine has antineoplastic and antiviral activity at low micromolar and submicromolar concentrations, and has been demonstrated to inhibit incorporation of amino acids into proteins and purine nucleotide synthesis.Related product price
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