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ChemicalBook >> CAS DataBase List >> 2(1H)-ISOQUINOLINECARBOXYLIC ACID, 3,4-DIHYDRO-7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-, 1,1-DIMETHYLETHYL ESTER

2(1H)-ISOQUINOLINECARBOXYLIC ACID, 3,4-DIHYDRO-7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-, 1,1-DIMETHYLETHYL ESTER

2(1H)-ISOQUINOLINECARBOXYLIC ACID, 3,4-DIHYDRO-7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-, 1,1-DIMETHYLETHYL ESTER price.
  • $123 - $6854
  • Product name: 2(1H)-ISOQUINOLINECARBOXYLIC ACID, 3,4-DIHYDRO-7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-, 1,1-DIMETHYLETHYL ESTER
  • CAS: 937048-76-5
  • MF: C20H30BNO4
  • MW: 359.27
  • EINECS:
  • MDL Number:MFCD11044674
  • Synonyms:2(1H)-ISOQUINOLINECARBOXYLIC ACID, 3,4-DIHYDRO-7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-, 1,1-DIMETHYLETHYL ESTER;tert-Butyl 7-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,4-tetrahydroisoquinoline-2-carboxylate;2-Boc-3,4-dihydro-1H-isoquinoline-7-boronic acid pinacol ester;7-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester;tert-Butyl 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl);tert-Butyl 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carbo;(2-(TERT-BUTOXYCARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL)BORONIC ACID PINACOL ESTER;tert-butyl 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,4-tetrahydroisoquinoline-2-carboxylate
16 prices
Selected condition：
Brand
  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • Chemenu
  • ChemScene
  • Crysdot
  • Matrix Scientific
  • TRC
Package
  • 5MG
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product number4628AJ
  • Product descriptiontert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate
  • Packaging5g
  • Price$6854
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number937048765
  • Product descriptiontert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate
  • Packaging1g
  • Price$1427.76
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA377111
  • Product descriptiontert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 95%
  • Packaging100mg
  • Price$123
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA377111
  • Product descriptiontert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 95%
  • Packaging250mg
  • Price$197
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA377111
  • Product descriptiontert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 95%
  • Packaging1g
  • Price$479
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBOR0005957
  • Product descriptionTERT-BUTYL-7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE 95.00%
  • Packaging1G
  • Price$1080.45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBOR0005957
  • Product descriptionTERT-BUTYL-7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE 95.00%
  • Packaging5MG
  • Price$499.36
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM219179
  • Product descriptiontert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 95%
  • Packaging1g
  • Price$486
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-W000580
  • Product descriptiontert-butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate
  • Packaging100mg
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-W000580
  • Product descriptiontert-butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate
  • Packaging250mg
  • Price$187
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-W000580
  • Product descriptiontert-butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate
  • Packaging1g
  • Price$491
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11009281
  • Product descriptiontert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 95+%
  • Packaging250mg
  • Price$456
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11009281
  • Product descriptiontert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 95+%
  • Packaging1g
  • Price$1141
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number132144
  • Product descriptiontert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 97%
  • Packaging5g
  • Price$5040
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number132144
  • Product descriptiontert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 97%
  • Packaging1g
  • Price$1764
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberT302610
  • Product description7-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-1H-isoquinoline-2-carboxylicAcidtert-ButylEster
  • Packaging500mg
  • Price$775
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4628AJ tert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 5g $6854 2021-12-16 Buy
Alichem 937048765 tert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 1g $1427.76 2021-12-16 Buy
Ambeed A377111 tert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 95% 100mg $123 2021-12-16 Buy
Ambeed A377111 tert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 95% 250mg $197 2021-12-16 Buy
Ambeed A377111 tert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 95% 1g $479 2021-12-16 Buy
American Custom Chemicals Corporation BOR0005957 TERT-BUTYL-7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE 95.00% 1G $1080.45 2021-12-16 Buy
American Custom Chemicals Corporation BOR0005957 TERT-BUTYL-7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE 95.00% 5MG $499.36 2021-12-16 Buy
Chemenu CM219179 tert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 95% 1g $486 2021-12-16 Buy
ChemScene CS-W000580 tert-butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 100mg $126 2021-12-16 Buy
ChemScene CS-W000580 tert-butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 250mg $187 2021-12-16 Buy
ChemScene CS-W000580 tert-butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 1g $491 2021-12-16 Buy
Crysdot CD11009281 tert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 95+% 250mg $456 2021-12-16 Buy
Crysdot CD11009281 tert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 95+% 1g $1141 2021-12-16 Buy
Matrix Scientific 132144 tert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 97% 5g $5040 2021-12-16 Buy
Matrix Scientific 132144 tert-Butyl7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 97% 1g $1764 2021-12-16 Buy
TRC T302610 7-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-1H-isoquinoline-2-carboxylicAcidtert-ButylEster 500mg $775 2021-12-16 Buy

Properties

Boiling point :462.2±45.0 °C(Predicted)
Density :1.10±0.1 g/cm3(Predicted)
storage temp. :2-8°C
pka :-1.54±0.20(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

7-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-1H-isoquinoline-2-carboxylic Acid tert-Butyl Ester is a reactant in the synthesis of tyrosine kinase inhibitors in the treatment of proliferative diseases.