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ChemicalBook >> CAS DataBase List >> 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite

2-Cyanoethyl N,N-diisopropylchlorophosphoramidite

2-Cyanoethyl N,N-diisopropylchlorophosphoramidite price.
  • $39.1 - $3496
  • Product name: 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite
  • CAS: 89992-70-1
  • MF: C9H18ClN2OP
  • MW: 236.68
  • EINECS:628-591-6
  • MDL Number:MFCD00011544
  • Synonyms:Phosphoramidochloridous acid, bis(1-methylethyl)-, 2-cyanoethyl ester;2-CYANOETHYL DIISOPROPYLCHLOROPHOSPHORAMIDITE, 14.0%-15.7% CL;2-Cyanoethoxy-N,N'-Diisopropyl Chlorophosphoramidate;2-CYANOETHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE;2-CYANOETHYL DIISDPROPYLCHLOROPHOSPHORAMIDITE;2-CYANOETHYL DIISOPROPYLCHLOROPHOSPHORAMIDITE;CHLORO(DIISOPROPYLAMINO)-BETA-CYANOETHOXYPHOSPHINE;CYANOETHYL N,N-DIISOPROPYL PHOSPHOAMIDOCHLORIDITE
15 prices
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Brand
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • Chemenu
  • JR MediChem
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 250mg
  • 1g
  • 2.5g
  • 5g
  • 25G
  • 500g
  • ManufacturerAlfa Aesar
  • Product numberL18575
  • Product description2-Cyanoethyl diisopropylchlorophosphoramidite, 95%
  • Packaging1g
  • Price$87.1
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberL18575
  • Product description2-Cyanoethyl diisopropylchlorophosphoramidite, 95%
  • Packaging5g
  • Price$288
  • Updated2024-03-01
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberING0005415
  • Product description2-CYANOETHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE 95.00%
  • Packaging1G
  • Price$465
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberING0005415
  • Product description2-CYANOETHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE 95.00%
  • Packaging5G
  • Price$615
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberING0005415
  • Product description2-CYANOETHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE 95.00%
  • Packaging25G
  • Price$1395
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM328519
  • Product description3-[chloro-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile 95%+
  • Packaging500g
  • Price$3496
  • Updated2021-12-16
  • Buy
  • ManufacturerJR MediChem
  • Product numberAS-2197
  • Product description2-Cyanoethyl N,N-diisopropylchlorophosphoramidite 98%
  • Packaging5g
  • Price$298
  • Updated2021-12-16
  • Buy
  • ManufacturerJR MediChem
  • Product numberAS-2197
  • Product description2-Cyanoethyl N,N-diisopropylchlorophosphoramidite 98%
  • Packaging25g
  • Price$680
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number8640
  • Product descriptionCyanoethylN,N-diisopropylphosphoamidochloridite
  • Packaging1g
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberM072000
  • Product description2-Cyanoethyl ≥97.0% (31P-NMR)
  • Packaging5g
  • Price$424
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number302309
  • Product description2-Cyanoethyl N,N-diisopropylchlorophosphoramidite Cl 13.5-15.5%
  • Packaging5g
  • Price$308
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number302309
  • Product description2-Cyanoethyl N,N-diisopropylchlorophosphoramidite Cl 13.5-15.5%
  • Packaging1g
  • Price$91.1
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number302309
  • Product description2-Cyanoethyl N,N-diisopropylchlorophosphoramidite Cl 13.5-15.5%
  • Packaging250mg
  • Price$39.1
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberC980000
  • Product descriptionCyanoethylN,N-DiisopropylPhosphoamidochloridite
  • Packaging1g
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC980000
  • Product descriptionCyanoethylN,N-DiisopropylPhosphoamidochloridite
  • Packaging2.5g
  • Price$150
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alfa Aesar L18575 2-Cyanoethyl diisopropylchlorophosphoramidite, 95% 1g $87.1 2024-03-01 Buy
Alfa Aesar L18575 2-Cyanoethyl diisopropylchlorophosphoramidite, 95% 5g $288 2024-03-01 Buy
American Custom Chemicals Corporation ING0005415 2-CYANOETHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE 95.00% 1G $465 2021-12-16 Buy
American Custom Chemicals Corporation ING0005415 2-CYANOETHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE 95.00% 5G $615 2021-12-16 Buy
American Custom Chemicals Corporation ING0005415 2-CYANOETHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE 95.00% 25G $1395 2021-12-16 Buy
Chemenu CM328519 3-[chloro-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile 95%+ 500g $3496 2021-12-16 Buy
JR MediChem AS-2197 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite 98% 5g $298 2021-12-16 Buy
JR MediChem AS-2197 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite 98% 25g $680 2021-12-16 Buy
Medical Isotopes, Inc. 8640 CyanoethylN,N-diisopropylphosphoamidochloridite 1g $290 2021-12-16 Buy
Sigma-Aldrich M072000 2-Cyanoethyl ≥97.0% (31P-NMR) 5g $424 2024-03-01 Buy
Sigma-Aldrich 302309 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite Cl 13.5-15.5% 5g $308 2024-03-01 Buy
Sigma-Aldrich 302309 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite Cl 13.5-15.5% 1g $91.1 2024-03-01 Buy
Sigma-Aldrich 302309 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite Cl 13.5-15.5% 250mg $39.1 2024-03-01 Buy
TRC C980000 CyanoethylN,N-DiisopropylPhosphoamidochloridite 1g $65 2021-12-16 Buy
TRC C980000 CyanoethylN,N-DiisopropylPhosphoamidochloridite 2.5g $150 2021-12-16 Buy

Properties

Boiling point :103-105°C 0,08mm
Density :1.061 g/mL at 25 °C(lit.)
refractive index :n20/D 1.479
Flash point :>230 °F
storage temp. :−20°C
solubility :Miscible with chloroform and dichloromethane.
form :Crystalline Powder
pka :0.83±0.70(Predicted)
color :clear to very slightly hazy colorless
Sensitive :Moisture Sensitive
BRN :3588525
Stability :Hygroscopic, Moisture Sensitive
InChI :InChI=1S/C9H18ClN2OP/c1-8(2)12(9(3)4)14(10)13-7-5-6-11/h8-9H,5,7H2,1-4H3
InChIKey :QWTBDIBOOIAZEF-UHFFFAOYSA-N
SMILES :P(N(C(C)C)C(C)C)(Cl)OCCC#N
CAS DataBase Reference :89992-70-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H250 Catches fire spontaneously if exposed to air Pyrophoric liquids; Pyrorophoric solids Category 1 Danger GHS hazard pictograms P210, P222, P280, P302+P334,P370+P378, P422
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P334 IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P370+P378 In case of fire: Use … for extinction.

Description

2-Cyanoethyl diisopropylchlorophosphoramidite is a useful intermediate in organic synthesis. It acts as a protecting reagent in DNA synthesis. It is involved in the selective monophosphorylation of carbohydrates and nucleosides. It plays an essential role in the conversion of protected ribonucleosides to phosphoramidites. It is also utilized as phosphitylating reagent for 3'-hydroxyl groups in the synthesis of oligodeoxyribonucleotides.

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