(1S,2S,6S,9R)-9-hydroxy-9-(hydroxymethyl)-2-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-oxabicyclo[4.3.0]nona-4,7-diene-5-carboxylic acid
![(1S,2S,6S,9R)-9-hydroxy-9-(hydroxymethyl)-2-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-oxabicyclo[4.3.0]nona-4,7-diene-5-carboxylic acid price.](/CAS/GIF/5945-50-6.gif)
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- $40 - $1095.15
- Product name: (1S,2S,6S,9R)-9-hydroxy-9-(hydroxymethyl)-2-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-oxabicyclo[4.3.0]nona-4,7-diene-5-carboxylic acid
- CAS: 5945-50-6
- MF: C16H22O11
- MW: 390.34
- EINECS:
- MDL Number:MFCD00238650
- Synonyms:(1S,2S,6S,9R)-9-hydroxy-9-(hydroxymethyl)-2-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-oxabicyclo[4.3.0]nona-4,7-diene-5-carboxylic acid;1α-(β-D-Glucopyranosyloxy)-1,4aα,7,7aα-tetrahydro-7β-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid;Monotropein;Morinda officinalis How;Monotropein, 98%, from Monotropa uniflora L.;Monotropeine;Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,7,7a-tetrahydro-7-hydroxy-7-(hydroxymethyl)-, (1S,4aS,7R,7aS)-;Monotropein >=98% (HPLC)
29 prices
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Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Usbiological
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250MG
- ManufacturerAK Scientific
- Product numberY0138
- Product descriptionMonotropein
- Packaging5mg
- Price$349
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0003630
- Product descriptionMONOTROPEIN 95.00%
- Packaging5MG
- Price$503.4
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0003630
- Product descriptionMONOTROPEIN 95.00%
- Packaging250MG
- Price$1095.15
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN2386
- Product descriptionMonotropein
- Packaging10mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN99523
- Product descriptionMonotropein
- Packaging20mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY068758
- Product descriptionMonotropein,98%,fromMonotropaunifloraLinn. ≥98%
- Packaging10mg
- Price$199.09
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2408
- Product descriptionMonotropein
- Packaging5mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2408
- Product descriptionMonotropein
- Packaging10mg
- Price$189
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2408
- Product descriptionMonotropein
- Packaging20mg
- Price$269
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2408
- Product descriptionMonotropein
- Packaging100mg
- Price$790
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594123
- Product descriptionMonotropein
- Packaging20mg
- Price$306
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594123
- Product descriptionMonotropein
- Packaging100mg
- Price$552.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb105447
- Product descriptionmonotropein >98%,Standard References Grade
- Packaging20mg
- Price$569.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM65578
- Product descriptionMonotropein
- Packaging1mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM65578
- Product descriptionMonotropein
- Packaging2mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM65578
- Product descriptionMonotropein
- Packaging5mg
- Price$150
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y0138 | Monotropein | 5mg | $349 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0003630 | MONOTROPEIN 95.00% | 5MG | $503.4 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0003630 | MONOTROPEIN 95.00% | 250MG | $1095.15 | 2021-12-16 | Buy |
| ApexBio Technology | N2386 | Monotropein | 10mg | $200 | 2021-12-16 | Buy |
| Arctom | CFN99523 | Monotropein | 20mg | $90 | 2021-12-16 | Buy |
| Arctom | SY068758 | Monotropein,98%,fromMonotropaunifloraLinn. ≥98% | 10mg | $199.09 | 2021-12-16 | Buy |
| AvaChem | 2408 | Monotropein | 5mg | $119 | 2021-12-16 | Buy |
| AvaChem | 2408 | Monotropein | 10mg | $189 | 2021-12-16 | Buy |
| AvaChem | 2408 | Monotropein | 20mg | $269 | 2021-12-16 | Buy |
| AvaChem | 2408 | Monotropein | 100mg | $790 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594123 | Monotropein | 20mg | $306 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594123 | Monotropein | 100mg | $552.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb105447 | monotropein >98%,Standard References Grade | 20mg | $569.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FM65578 | Monotropein | 1mg | $40 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FM65578 | Monotropein | 2mg | $70 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FM65578 | Monotropein | 5mg | $150 | 2021-12-16 | Buy |
Properties
Melting point :170-173 °C
Boiling point :717.6±60.0 °C(Predicted)
Density :1.73±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in methanol and water
form :powder
pka :4.31±0.60(Predicted)
color :White
Boiling point :717.6±60.0 °C(Predicted)
Density :1.73±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in methanol and water
form :powder
pka :4.31±0.60(Predicted)
color :White
Safety Information
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Description
Monotropein is an iridoid glycoside originally isolated from M. officinalis roots and has diverse biological activities. It increases cell viability and migration of bone marrow-derived endothelial progenitor cells (BM-EPCs) when used at concentrations ranging from 0.1 to 1,000 μM. Monotropein inhibits apoptosis and reduces levels of matrix metalloproteinase-3 (MMP-3) and MMP-13 in chondrocytes. It inhibits LPS-induced nuclear translocation of NF-κB and reduces COX-2, inducible nitric oxide synthase (iNOS), TNF-α, and IL-1β mRNA expression in RAW 264.7 cells. Monotropein (100 and 200 mg/kg) reduces colonic myeloperoxidase (MPO) activity, COX-2 and iNOS mRNA expression, and disease severity in a mouse model of ulcerative colitis induced by dextran sulfate sodium (DSS; ). It increases bone mineral content, bone mineral density, and improves bone microstructure in ovariectomized mice when administered at doses of 40 or 80 mg/kg. Monotropein (20 and 30 mg/kg) reduces acetic acid-induced writhing in mice and carrageenan-induced paw edema in rats. It also decreases macrophage infiltration and wound healing time and increases blood vessel formation in a rat model of wound healing.More related product prices
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![(1S,2S,6S,9R)-9-hydroxy-9-(hydroxymethyl)-2-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-oxabicyclo[4.3.0]nona-4,7-diene-5-carboxylic acid](https://img.chemicalbook.com/ProductImageEN/2019-5/small/8f04fe1e-723d-4899-9310-c2f58d63d94f.jpg){kind=small}
