Parthenolide
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- $28 - $800
- Product name: Parthenolide
- CAS: 20554-84-1
- MF: C15H20O3
- MW: 248.32
- EINECS:692-532-0
- MDL Number:MFCD00134592
- Synonyms:[1aR-(1aR*,4E,7aS*,10aS*,-10bR*)]-2,3-6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one;(1aR,4E,7aS,10aS,10bS)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one;4,5α-Epoxy-6β-hydroxygermacra-1(10),11(13)-dien-12-oic acid γ-lactone;4,5alpha-epoxy-6beta-hydroxy-germacra-1(10),11(13)-dien-12-oic acid gamma-lactone;Germacra-1(10),11(13)-dien-12-oic acid, 4,5-alpha-epoxy-6-beta-hydroxy-, gamma-lactone;Parthenolide;Parthenolide ((-)-Parthenolide);PartheNAlide
52 prices
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Brand
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- JR MediChem
- Labseeker
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 1unit
- 5mg
- 10mg
- 20mg
- 10mM(in 1mL DMSO)
- 25mg
- 50mg
- 100MG
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- 5g
- 10g
- ManufacturerAdipogen Life Sciences
- Product numberCDX-P0297-M025
- Product descriptionParthenolide ≥98%(HPLC)
- Packaging25mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberV0355
- Product descriptionParthenolide
- Packaging200mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000298
- Product descriptionPARTHENOLIDE 95.00%
- Packaging25MG
- Price$150.15
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000298
- Product descriptionPARTHENOLIDE 95.00%
- Packaging100MG
- Price$642.99
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN1315
- Product descriptionParthenolide
- Packaging250mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN1315
- Product descriptionParthenolide
- Packaging10mM(in 1mL DMSO)
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN1315
- Product descriptionParthenolide
- Packaging100mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN1315
- Product descriptionParthenolide
- Packaging50mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN1315
- Product descriptionParthenolide
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIP0110
- Product descriptionParthenolide
- Packaging50mg
- Price$73
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIP0110
- Product descriptionParthenolide
- Packaging100mg
- Price$116
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIP0110
- Product descriptionParthenolide
- Packaging250mg
- Price$254
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS020015
- Product description(-)-Parthenolide 97%
- Packaging50mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS020015
- Product description(-)-Parthenolide 97%
- Packaging100mg
- Price$38
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN98034
- Product descriptionParthenolide ≥98%
- Packaging20mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS020015
- Product description(-)-Parthenolide 97%
- Packaging250mg
- Price$56
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | CDX-P0297-M025 | Parthenolide ≥98%(HPLC) | 25mg | $59 | 2021-12-16 | Buy |
| AK Scientific | V0355 | Parthenolide | 200mg | $144 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000298 | PARTHENOLIDE 95.00% | 25MG | $150.15 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000298 | PARTHENOLIDE 95.00% | 100MG | $642.99 | 2021-12-16 | Buy |
| ApexBio Technology | N1315 | Parthenolide | 250mg | $140 | 2021-12-16 | Buy |
| ApexBio Technology | N1315 | Parthenolide | 10mM(in 1mL DMSO) | $80 | 2021-12-16 | Buy |
| ApexBio Technology | N1315 | Parthenolide | 100mg | $65 | 2021-12-16 | Buy |
| ApexBio Technology | N1315 | Parthenolide | 50mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | N1315 | Parthenolide | 1unit | $28 | 2021-12-16 | Buy |
| Apolloscientific | BIP0110 | Parthenolide | 50mg | $73 | 2021-12-16 | Buy |
| Apolloscientific | BIP0110 | Parthenolide | 100mg | $116 | 2021-12-16 | Buy |
| Apolloscientific | BIP0110 | Parthenolide | 250mg | $254 | 2021-12-16 | Buy |
| Arctom | AS020015 | (-)-Parthenolide 97% | 50mg | $30 | 2021-12-16 | Buy |
| Arctom | AS020015 | (-)-Parthenolide 97% | 100mg | $38 | 2021-12-16 | Buy |
| Arctom | CFN98034 | Parthenolide ≥98% | 20mg | $40 | 2021-12-16 | Buy |
| Arctom | AS020015 | (-)-Parthenolide 97% | 250mg | $56 | 2021-12-16 | Buy |
Properties
Melting point :115-116 °C (lit.)
alpha :D20 -81.4° (c = 1.04 in chloroform); D22 -71.4° (c = 0.220 in CH2Cl2)
Boiling point :394.1±42.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 20 mg/ml)
form :White solid
color :White
Merck :14,7048
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :InChI=1S/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5+/t11-,12-,13+,15+/m0/s1
InChIKey :KTEXNACQROZXEV-PVLRGYAZSA-N
SMILES :O1C(=O)C(=C)[C@]2([H])CCC(C)=CCC[C@@]3(C)O[C@]3([H])[C@@]12[H] |t:10|
LogP :2.424 (est)
CAS DataBase Reference :20554-84-1
alpha :D20 -81.4° (c = 1.04 in chloroform); D22 -71.4° (c = 0.220 in CH2Cl2)
Boiling point :394.1±42.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 20 mg/ml)
form :White solid
color :White
Merck :14,7048
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :InChI=1S/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5+/t11-,12-,13+,15+/m0/s1
InChIKey :KTEXNACQROZXEV-PVLRGYAZSA-N
SMILES :O1C(=O)C(=C)[C@]2([H])CCC(C)=CCC[C@@]3(C)O[C@]3([H])[C@@]12[H] |t:10|
LogP :2.424 (est)
CAS DataBase Reference :20554-84-1
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Parthenolide is a sesquiterpene lactone from the plant feverfew (T. parthenium). It inhibits the growth of the promastigote form of L. amazonensis (IC50 = 3.6 μg/ml). Parthenolide also induces apoptosis in cancer cells, at least in part by inhibiting NF-κB- and STAT-mediated anti-apoptotic gene transcription. This compound has also been shown to block inflammation by inhibiting signaling through NF-κB. Inhibition of NF-κB by parthenolide can be achieved by direct binding of the pattern recognition receptor NOD2 by parthenolide.Related product price
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Suppliers and manufacturers
Accendatech Co., Ltd.
Shanghai Zheyan Biotech Co., Ltd.
Biochempartner
Chengdu Biopurify Phytochemicals Ltd.
