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ChemicalBook >> CAS DataBase List >> N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE

N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE

N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE price.
  • $62 - $815
  • Product name: N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE
  • CAS: 269390-69-4
  • MF: C19H16ClN3O
  • MW: 337.8
  • EINECS:
  • MDL Number:MFCD09037563
  • Synonyms:VEGFR Tyrosine Kinase Inhibitor II;N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE;VEGF RECEPTOR TYROSINE KINASE INHIBITOR II;Valatinib;Benzamide, N-(4-chlorophenyl)-2-[(4-pyridinylmethyl)amino]-;VEGFR-IN-1;VEGFR Tyrosine Kinase;VEGFR IN 1,VEGFRIN1
9 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 2.5mg
  • 5MG
  • 10mg
  • ManufacturerAK Scientific
  • Product number3074CR
  • Product descriptionN-(4-Chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide
  • Packaging1mg
  • Price$166
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0352681
  • Product descriptionN-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE 95.00%
  • Packaging5MG
  • Price$495.87
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4603
  • Product descriptionVEGFRTyrosineKinaseInhibitorII
  • Packaging1mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4603
  • Product descriptionVEGFRTyrosineKinaseInhibitorII
  • Packaging5mg
  • Price$204
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17654
  • Product descriptionVEGFR Tyrosine Kinase Inhibitor II ≥98%
  • Packaging1mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17654
  • Product descriptionVEGFR Tyrosine Kinase Inhibitor II ≥98%
  • Packaging5mg
  • Price$180
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number676481
  • Product descriptionVEGFR Tyrosine Kinase Inhibitor II - CAS 269390-69-4 - Calbiochem
  • Packaging5MG
  • Price$207
  • Updated2022-05-15
  • Buy
  • ManufacturerTRC
  • Product numberV756803
  • Product descriptionVEGFRTyrosineKinaseInhibitorII
  • Packaging2.5mg
  • Price$270
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberV756803
  • Product descriptionVEGFRTyrosineKinaseInhibitorII
  • Packaging10mg
  • Price$815
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3074CR N-(4-Chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide 1mg $166 2021-12-16 Buy
American Custom Chemicals Corporation HCH0352681 N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE 95.00% 5MG $495.87 2021-12-16 Buy
ApexBio Technology C4603 VEGFRTyrosineKinaseInhibitorII 1mg $68 2021-12-16 Buy
ApexBio Technology C4603 VEGFRTyrosineKinaseInhibitorII 5mg $204 2021-12-16 Buy
Cayman Chemical 17654 VEGFR Tyrosine Kinase Inhibitor II ≥98% 1mg $62 2024-03-01 Buy
Cayman Chemical 17654 VEGFR Tyrosine Kinase Inhibitor II ≥98% 5mg $180 2024-03-01 Buy
Sigma-Aldrich 676481 VEGFR Tyrosine Kinase Inhibitor II - CAS 269390-69-4 - Calbiochem 5MG $207 2022-05-15 Buy
TRC V756803 VEGFRTyrosineKinaseInhibitorII 2.5mg $270 2021-12-16 Buy
TRC V756803 VEGFRTyrosineKinaseInhibitorII 10mg $815 2021-12-16 Buy

Properties

Boiling point :463.6±40.0 °C(Predicted)
Density :1.331±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 25 mg/ml
form :A crystalline solid
pka :12.62±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

VEGFR tyrosine kinase inhibitor II is a pyridinyl-anthranilamide compound that inhibits the kinase activities of VEGFR2 (KDR), VEGFR1 (FLT1), and c-Kit (IC50s = 20, 180, and 240 nM, respectively). It displays minimal activity against c-Src and EGFR (IC50s = 7 and 7.3 μM, respectively) and is inactive against Cdk1, c-Met, IGF-1R, and PKA (IC50s > 10 μM). VEGFR tyrosine kinase inhibitor II has been investigated for its potential to inhibit tumor induced angiogenesis.

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