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ChemicalBook >> CAS DataBase List >> TYRPHOSTIN AG 126

TYRPHOSTIN AG 126

TYRPHOSTIN AG 126 price.
  • $28 - $2109
  • Product name: TYRPHOSTIN AG 126
  • CAS: 118409-62-4
  • MF: C10H5N3O3
  • MW: 215.16
  • EINECS:
  • MDL Number:MFCD00236448
  • Synonyms:RARECHEM AL BX 0673;TYRPHOSTIN A10;TYRPHOSTIN AG 126;ag127 ;AG 126;ALPHA-CYANO-(3-HYDROXY-4-NITRO)CINNAMONITRILE;[3-HYDROXY-4-NITROBENZYLIDENE]MALONONITRILE;Tyrphostin 126
35 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 1MG
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number0073BA
  • Product descriptionTyrphostin AG-126
  • Packaging50mg
  • Price$197
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67211
  • Product descriptionTyrphostin AG-126
  • Packaging5mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA860936
  • Product descriptionAG 126 98%
  • Packaging5mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA860936
  • Product descriptionAG 126 98%
  • Packaging10mg
  • Price$106
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA860936
  • Product descriptionAG 126 98%
  • Packaging25mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA860936
  • Product descriptionAG 126 98%
  • Packaging50mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000256
  • Product descriptionTYRPHOSTIN A-10 95.00%
  • Packaging1MG
  • Price$432
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000256
  • Product descriptionTYRPHOSTIN A-10 95.00%
  • Packaging5MG
  • Price$703.86
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000256
  • Product descriptionTYRPHOSTIN A-10 95.00%
  • Packaging25MG
  • Price$1034.48
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4338
  • Product descriptionAG 126
  • Packaging5mg
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4338
  • Product descriptionAG 126
  • Packaging10mg
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4338
  • Product descriptionAG 126
  • Packaging25mg
  • Price$435
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0202
  • Product descriptionAG 126
  • Packaging25mg
  • Price$372
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0202
  • Product descriptionAG 126
  • Packaging10mg
  • Price$183
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0202
  • Product descriptionAG 126
  • Packaging5mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13297
  • Product descriptionAG 126 ≥95%
  • Packaging1mg
  • Price$28
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0073BA Tyrphostin AG-126 50mg $197 2021-12-16 Buy
Alfa Aesar J67211 Tyrphostin AG-126 5mg $132 2021-12-16 Buy
Ambeed A860936 AG 126 98% 5mg $59 2021-12-16 Buy
Ambeed A860936 AG 126 98% 10mg $106 2021-12-16 Buy
Ambeed A860936 AG 126 98% 25mg $138 2021-12-16 Buy
Ambeed A860936 AG 126 98% 50mg $180 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000256 TYRPHOSTIN A-10 95.00% 1MG $432 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000256 TYRPHOSTIN A-10 95.00% 5MG $703.86 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000256 TYRPHOSTIN A-10 95.00% 25MG $1034.48 2021-12-16 Buy
ApexBio Technology C4338 AG 126 5mg $104 2021-12-16 Buy
ApexBio Technology C4338 AG 126 10mg $192 2021-12-16 Buy
ApexBio Technology C4338 AG 126 25mg $435 2021-12-16 Buy
Apolloscientific BISN0202 AG 126 25mg $372 2021-12-16 Buy
Apolloscientific BISN0202 AG 126 10mg $183 2021-12-16 Buy
Apolloscientific BISN0202 AG 126 5mg $115 2021-12-16 Buy
Cayman Chemical 13297 AG 126 ≥95% 1mg $28 2024-03-01 Buy

Properties

storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :≤0.15mg/ml in ethanol;10mg/ml in DMSO;10mg/ml in dimethyl formamide
form :Yellow solid
color :Light yellow to yellow
Sensitive :Light Sensitive

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Tyrphostins are a family of protein tyrosine kinase inhibitors originally developed to inhibit cell growth by blocking the activity of certain growth factor receptor kinases (GFRK). The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM. It blocks the production of TNF-α in vitro and in vivo, attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response in diverse animal models. AG-126 is a poor inhibitor of epidermal GFRK (IC50 = 450 μM) and platelet-derived GFRK (IC50 > 100 μM).