Zoledronate disodium tetrahydrate
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- $49.5 - $1720
- Product name: Zoledronate disodium tetrahydrate
- CAS: 165800-07-7
- MF: C5H13N2NaO8P2
- MW: 314.1
- EINECS:
- MDL Number:MFCD07357645
- Synonyms:ZOLEDRONATE DISODIUM, TETRAHYDRATE;ZOLEDRONIC ACID, DISODIUM SALT, TETRAHYDRATE;Zoledronate Disodium, CGP-42446A;(1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid disodium salt tetrahydrate;CGP-42446A;Zoledronate DisodiuM (C5H8N2Na2O7P24H2O);Sodium (1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl)phosphonate tetrahydrate;Disodium salt tetrahydrate
12 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- Chemenu
- Crysdot
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 25mg
- 50MG
- 100mg
- 250mg
- 500MG
- 1g
- ManufacturerAK Scientific
- Product number8418AA
- Product descriptionSodium(1-hydroxy-2-(1H-imidazol-1-yl)-1-Phosphonoethyl)phosphonatetetrahydrate
- Packaging25mg
- Price$116
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8418AA
- Product descriptionSodium(1-hydroxy-2-(1H-imidazol-1-yl)-1-Phosphonoethyl)phosphonatetetrahydrate
- Packaging100mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004653
- Product descriptionZOLEDRONATE DISODIUM TETRAHYDRATE 95.00%
- Packaging50MG
- Price$704.55
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004653
- Product descriptionZOLEDRONATE DISODIUM TETRAHYDRATE 95.00%
- Packaging500MG
- Price$1593.9
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFZ28773
- Product descriptionZoledronic acid, disodium salt, tetrahydrate
- Packaging25mg
- Price$49.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFZ28773
- Product descriptionZoledronic acid, disodium salt, tetrahydrate
- Packaging100mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM187425
- Product descriptionSodium(1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl)phosphonatetetrahydrate 95%
- Packaging1g
- Price$729
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD61001150
- Product descriptionSodium(1-hydroxy-2-(1H-imidazol-1-yl)-1-Phosphonoethyl)phosphonatetetrahydrate 95+%
- Packaging1g
- Price$772
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number095289
- Product descriptionSodium (1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl)phosphonate tetrahydrate 95+%
- Packaging1g
- Price$1647
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number14214
- Product descriptionZoledronicAcidDisodiumSaltTetrahydrate
- Packaging250mg
- Price$1720
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberZ623500
- Product descriptionZoledronicAcidDisodiumSaltTetrahydrate
- Packaging100mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product numberZ0787
- Product descriptionZoledronic Acid, Disodium Salt, Tetrahydrate
- Packaging50mg
- Price$283
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8418AA | Sodium(1-hydroxy-2-(1H-imidazol-1-yl)-1-Phosphonoethyl)phosphonatetetrahydrate | 25mg | $116 | 2021-12-16 | Buy |
| AK Scientific | 8418AA | Sodium(1-hydroxy-2-(1H-imidazol-1-yl)-1-Phosphonoethyl)phosphonatetetrahydrate | 100mg | $210 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004653 | ZOLEDRONATE DISODIUM TETRAHYDRATE 95.00% | 50MG | $704.55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004653 | ZOLEDRONATE DISODIUM TETRAHYDRATE 95.00% | 500MG | $1593.9 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FZ28773 | Zoledronic acid, disodium salt, tetrahydrate | 25mg | $49.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FZ28773 | Zoledronic acid, disodium salt, tetrahydrate | 100mg | $119 | 2021-12-16 | Buy |
| Chemenu | CM187425 | Sodium(1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl)phosphonatetetrahydrate 95% | 1g | $729 | 2021-12-16 | Buy |
| Crysdot | CD61001150 | Sodium(1-hydroxy-2-(1H-imidazol-1-yl)-1-Phosphonoethyl)phosphonatetetrahydrate 95+% | 1g | $772 | 2021-12-16 | Buy |
| Matrix Scientific | 095289 | Sodium (1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl)phosphonate tetrahydrate 95+% | 1g | $1647 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 14214 | ZoledronicAcidDisodiumSaltTetrahydrate | 250mg | $1720 | 2021-12-16 | Buy |
| TRC | Z623500 | ZoledronicAcidDisodiumSaltTetrahydrate | 100mg | $250 | 2021-12-16 | Buy |
| Usbiological | Z0787 | Zoledronic Acid, Disodium Salt, Tetrahydrate | 50mg | $283 | 2021-12-16 | Buy |
Properties
Melting point :305-307°C
storage temp. :Sealed in dry,Room Temperature
solubility :Methanol (Slightly, Heated, Sonicated), Water (Slightly, Heated)
form :Solid
color :White to Off-White
storage temp. :Sealed in dry,Room Temperature
solubility :Methanol (Slightly, Heated, Sonicated), Water (Slightly, Heated)
form :Solid
color :White to Off-White
Safety Information
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Description
Zoledronate was introduced in Canada as a lyophilized powder in vials for infusion as solution in the treatment of tumor-induced hypercalcemia. This third-generation bisphosphonate can be obtained by reaction of 2-(1-imidazolyl)acetic acid hydrochloride with phosphorous trichloride followed by hydrolysis in concentrated hydrochloric acid, Zoledronate originated from a medicinal chemistry program started at Novartis, Switzerland in 1986 and aimed at discovering a follow-up to pamidronate for the treatment of osteoporosis and metastatic bone disease. It has highly potent inhibitory effect on hypercalcemia induced by vitamin Ds both in vitro in mouse calvarial cultures and in viva in the thyroparathyroidectomized rat. It is respectively 100 and 850-fold more potent than pamidronate in the former and latter tests. Clinically, it was demonstrated that zoledronate achieved normalized serum calcium concentrations in a significantly higher percentage of cancer patients compared to pamidronate. The 5 minute infusion with zoledronate was more convenient than the 2 hour infusion necessary with pamidronate.Related product price
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