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ChemicalBook >> CAS DataBase List >> tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate

tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate

tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate price.
  • $53 - $708.75
  • Product name: tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate
  • CAS: 1628047-84-6
  • MF: C18H17BrN2O3
  • MW: 389.24
  • EINECS:942-459-8
  • MDL Number:MFCD28334265
  • Synonyms:tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate;tert-butyl 4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate;ABT199 intermediate 2;4-Bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoic acid 1,1-dimethylethyl ester;2575SM2;Benzoic acid, 4-bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-, 1,1-dimethylethyl ester;2-Methyl-2-propanyl 4-bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate;Tert-butyl 4-bromo-2-{1H-pyrrolo[2,3-b]pyridine -5- yloxy}benzoate
9 prices
Selected condition：
Brand
  • Alichem
  • Chemenu
  • ChemScene
  • Crysdot
  • TRC
Package
  • 1g
  • 5g
  • 10g
  • 25g
  • ManufacturerAlichem
  • Product number1628047846
  • Product descriptiontert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate
  • Packaging25g
  • Price$708.75
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105014
  • Product descriptiontert-butyl4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+
  • Packaging10g
  • Price$268
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105014
  • Product descriptiontert-butyl4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+
  • Packaging5g
  • Price$141
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105014
  • Product descriptiontert-butyl4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+
  • Packaging1g
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-B1514
  • Product descriptiontert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate
  • Packaging5g
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-B1514
  • Product descriptiontert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate
  • Packaging10g
  • Price$178
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11242995
  • Product descriptiontert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 97%
  • Packaging10g
  • Price$295
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11242995
  • Product descriptiontert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 97%
  • Packaging5g
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB694160
  • Product descriptiontert-?Butyl4-?Bromo-?2-?(1H-?pyrrolo[2,?3-?b]?pyridin-?5-?yloxy)benzoate
  • Packaging5g
  • Price$495
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alichem 1628047846 tert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 25g $708.75 2021-12-16 Buy
Chemenu CM105014 tert-butyl4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+ 10g $268 2021-12-16 Buy
Chemenu CM105014 tert-butyl4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+ 5g $141 2021-12-16 Buy
Chemenu CM105014 tert-butyl4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+ 1g $53 2021-12-16 Buy
ChemScene CS-B1514 tert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 5g $95 2021-12-16 Buy
ChemScene CS-B1514 tert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 10g $178 2021-12-16 Buy
Crysdot CD11242995 tert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 97% 10g $295 2021-12-16 Buy
Crysdot CD11242995 tert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 97% 5g $150 2021-12-16 Buy
TRC B694160 tert-?Butyl4-?Bromo-?2-?(1H-?pyrrolo[2,?3-?b]?pyridin-?5-?yloxy)benzoate 5g $495 2021-12-16 Buy

Properties

Melting point :188 - 190°C
Density :1.445±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), DMSO (Slightly)
pka :13.26±0.40(Predicted)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

tert-?Butyl 4-?Bromo-?2-?(1H-?pyrrolo[2,?3-?b]?pyridin-?5-?yloxy)benzoate is used in the synthesis of apoptosis-inducing agents. Intermediate of Venetoclax (A112430), a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets.