| Identification | Back Directory | [Name]
tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate | [CAS]
1628047-84-6 | [Synonyms]
2575SM2
ABT199 intermediate 2
tert-butyl 4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate
tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate
2-Methyl-2-propanyl 4-bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate
4-Bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoic acid 1,1-dimethylethyl ester
Benzoic acid, 4-bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-, 1,1-dimethylethyl ester | [EINECS(EC#)]
942-459-8 | [Molecular Formula]
C18H17BrN2O3 | [MDL Number]
MFCD28334265 | [MOL File]
1628047-84-6.mol | [Molecular Weight]
389.24 |
| Chemical Properties | Back Directory | [Melting point ]
188 - 190°C | [density ]
1.445±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
13.26±0.40(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
tert-?Butyl 4-?Bromo-?2-?(1H-?pyrrolo[2,?3-?b]?pyridin-?5-?yloxy)benzoate is used in the synthesis of apoptosis-inducing agents. Intermediate of Venetoclax (A112430), a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets. |
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