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ChemicalBook >> CAS DataBase List >> 3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine

3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine

3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine price.
  • $37 - $2000
  • Product name: 3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine
  • CAS: 1254977-87-1
  • MF: C22H23F3N4
  • MW: 400.44
  • EINECS:
  • MDL Number:MFCD22199231
  • Synonyms:3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine;JNJ42153605 (on going);JNJ-42153605;JNJ42153605;CS-2446;3-(Cyclopropylmethyl)-7-(4-phenyl-1-piperidinyl)-8-(trifluorometh yl)[1,2,4]triazolo[4,3-a]pyridine;1,2,4-Triazolo[4,3-a]pyridine, 3-(cyclopropylmethyl)-7-(4-phenyl-1-piperidinyl)-8-(trifluoromethyl)-;Inhibitor,JNJ42153605,Metabotropic glutamate receptors,JNJ-42153605,inhibit,JNJ 42153605,mGluR
11 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number3032DH
  • Product description3-(Cyclopropylmethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
  • Packaging1mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21984
  • Product descriptionJNJ-42153605
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21984
  • Product descriptionJNJ-42153605
  • Packaging5mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21984
  • Product descriptionJNJ-42153605
  • Packaging10mg
  • Price$283
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21984
  • Product descriptionJNJ-42153605
  • Packaging25mg
  • Price$618
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6317
  • Product descriptionJNJ-42153605 99.00%
  • Packaging5mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6317
  • Product descriptionJNJ-42153605 99.00%
  • Packaging10mg
  • Price$264
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6317
  • Product descriptionJNJ-42153605 99.00%
  • Packaging50mg
  • Price$792
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6317
  • Product descriptionJNJ-42153605 99.00%
  • Packaging100mg
  • Price$1140
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7843
  • Product descriptionJNJ42153605 >98%
  • Packaging250mg
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7843
  • Product descriptionJNJ42153605 >98%
  • Packaging1g
  • Price$2000
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3032DH 3-(Cyclopropylmethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine 1mg $139 2021-12-16 Buy
Cayman Chemical 21984 JNJ-42153605 1mg $37 2024-03-01 Buy
Cayman Chemical 21984 JNJ-42153605 5mg $161 2024-03-01 Buy
Cayman Chemical 21984 JNJ-42153605 10mg $283 2024-03-01 Buy
Cayman Chemical 21984 JNJ-42153605 25mg $618 2024-03-01 Buy
ChemScene CS-6317 JNJ-42153605 99.00% 5mg $180 2021-12-16 Buy
ChemScene CS-6317 JNJ-42153605 99.00% 10mg $264 2021-12-16 Buy
ChemScene CS-6317 JNJ-42153605 99.00% 50mg $792 2021-12-16 Buy
ChemScene CS-6317 JNJ-42153605 99.00% 100mg $1140 2021-12-16 Buy
DC Chemicals DC7843 JNJ42153605 >98% 250mg $1000 2021-12-16 Buy
DC Chemicals DC7843 JNJ42153605 >98% 1g $2000 2021-12-16 Buy

Properties

Density :1.38±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF:30.0(Max Conc. mg/mL);74.92(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.62(Max Conc. mM)
DMSO:10.34(Max Conc. mg/mL);25.81(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);24.97(Max Conc. mM) form :A crystalline solid
pka :3.07±0.30(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

JNJ-42153605 is a positive allosteric modulator of metabotropic glutamate receptor 2 (mGluR2; EC50 = 17 nM in CHO cells expressing the human receptor). In vivo, JNJ-42153605 (3 mg/kg) inhibits mGluR2-mediated rapid eye movement (REM) sleep in rats. It also reverses phencyclidine-induced hyperlocomotion in mice (ED50 = 5.4 mg/kg).