N,O-Bis(trimethylsilyl)acetamide
- $18 - $3404.8
- Product name: N,O-Bis(trimethylsilyl)acetamide
- CAS: 10416-59-8
- MF: C8H21NOSi2
- MW: 203.43
- EINECS:233-892-7
- MDL Number:MFCD00008270
- Synonyms:n-(trimethylsilyl)-acetimidicacitrimethylsilylester ;n-(trimethylsilyl)-ethanimidicacitrimethylsilylester ;Trimethylsilyl N-trimethylsilylacetamidate;NO-Bis (trimethylsilyl) acetamide 90+ % gas chromatography;N,O-Bis(trimethylsilyl)acetamide Kit TMS-BA (25% in Acetonitrile) 1 ml * 8 / Reaction vial, capacity 2 ml * 8;Trimethylsilyl (1E)-N-[(E)-trimethylsilyl]ethanimidoate;Acetimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester;CB2500
46 prices
Selected condition:
Brand
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- Apolloscientific
- Biosynth Carbosynth
- Chem-Impex
- Frontier Specialty Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Oakwood
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- TRC
Package
- 5g
- 5ml
- 10ml
- 10x1ml
- 12mL
- 25g
- 25mL
- 50g
- 100g
- 100ml
- 250g
- 500g
- 1l
- 1kg
- 2Kg
- 5KG
- 10KG
- 1kit
- ManufacturerAK Scientific
- Product numberX7204
- Product descriptionN,O-Bis(trimethylsilyl)acetamide
- Packaging100g
- Price$126
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberL00183
- Product descriptionN,O-Bis(trimethylsilyl)acetamide, 95%
- Packaging25g
- Price$43.5
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberL00183
- Product descriptionN,O-Bis(trimethylsilyl)acetamide, 95%
- Packaging100g
- Price$108
- Updated2024-03-01
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberORS0004978
- Product descriptionN,O-BIS(TRIMETHYLSILYL)ACETAMIDE 95.00%
- Packaging100G
- Price$2333.1
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberOR5155A
- Product descriptionTrimethylsilyl N-(trimethylsilyl)acetimidate
- Packaging100g
- Price$21
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberOR5155A
- Product descriptionTrimethylsilyl N-(trimethylsilyl)acetimidate
- Packaging500g
- Price$57
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB03098
- Product descriptionN,O-Bis(trimethylsilyl) acetamide
- Packaging100g
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB03098
- Product descriptionN,O-Bis(trimethylsilyl) acetamide
- Packaging250g
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB03098
- Product descriptionN,O-Bis(trimethylsilyl) acetamide
- Packaging500g
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB03098
- Product descriptionN,O-Bis(trimethylsilyl) acetamide
- Packaging1kg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB03098
- Product descriptionN,O-Bis(trimethylsilyl) acetamide
- Packaging2Kg
- Price$380
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number30800
- Product descriptionN,O-Bis(trimethylsilyl)acetamide,≥98%(GC)Hazmat ≥98%(GC)
- Packaging25G
- Price$27.66
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number30800
- Product descriptionN,O-Bis(trimethylsilyl)acetamide,98%(GC) 98%(GC)
- Packaging100G
- Price$53.2
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number30800
- Product descriptionN,O-Bis(trimethylsilyl)acetamide,98%(GC) 98%(GC)
- Packaging250G
- Price$95.76
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number30800
- Product descriptionN,O-Bis(trimethylsilyl)acetamide,≥98%(GC)Hazmat ≥98%(GC)
- Packaging1KG
- Price$376.23
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number30800
- Product descriptionN,O-Bis(trimethylsilyl)acetamide,98%(GC) 98%(GC)
- Packaging5KG
- Price$1787.52
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | X7204 | N,O-Bis(trimethylsilyl)acetamide | 100g | $126 | 2021-12-16 | Buy |
Alfa Aesar | L00183 | N,O-Bis(trimethylsilyl)acetamide, 95% | 25g | $43.5 | 2024-03-01 | Buy |
Alfa Aesar | L00183 | N,O-Bis(trimethylsilyl)acetamide, 95% | 100g | $108 | 2024-03-01 | Buy |
American Custom Chemicals Corporation | ORS0004978 | N,O-BIS(TRIMETHYLSILYL)ACETAMIDE 95.00% | 100G | $2333.1 | 2021-12-16 | Buy |
Apolloscientific | OR5155A | Trimethylsilyl N-(trimethylsilyl)acetimidate | 100g | $21 | 2021-12-16 | Buy |
Apolloscientific | OR5155A | Trimethylsilyl N-(trimethylsilyl)acetimidate | 500g | $57 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB03098 | N,O-Bis(trimethylsilyl) acetamide | 100g | $55 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB03098 | N,O-Bis(trimethylsilyl) acetamide | 250g | $95 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB03098 | N,O-Bis(trimethylsilyl) acetamide | 500g | $130 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB03098 | N,O-Bis(trimethylsilyl) acetamide | 1kg | $200 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB03098 | N,O-Bis(trimethylsilyl) acetamide | 2Kg | $380 | 2021-12-16 | Buy |
Chem-Impex | 30800 | N,O-Bis(trimethylsilyl)acetamide,≥98%(GC)Hazmat ≥98%(GC) | 25G | $27.66 | 2021-12-16 | Buy |
Chem-Impex | 30800 | N,O-Bis(trimethylsilyl)acetamide,98%(GC) 98%(GC) | 100G | $53.2 | 2021-12-16 | Buy |
Chem-Impex | 30800 | N,O-Bis(trimethylsilyl)acetamide,98%(GC) 98%(GC) | 250G | $95.76 | 2021-12-16 | Buy |
Chem-Impex | 30800 | N,O-Bis(trimethylsilyl)acetamide,≥98%(GC)Hazmat ≥98%(GC) | 1KG | $376.23 | 2021-12-16 | Buy |
Chem-Impex | 30800 | N,O-Bis(trimethylsilyl)acetamide,98%(GC) 98%(GC) | 5KG | $1787.52 | 2021-12-16 | Buy |
Properties
Melting point :24 °C
Boiling point :71-73 °C35 mm Hg(lit.)
Density :0.832 g/mL at 20 °C(lit.)
vapor pressure :10 hPa (50 °C)
refractive index :n20/D 1.417(lit.)
Flash point :53 °F
storage temp. :Store below +30°C.
solubility :Miscible with many nonpolar and polar aprotic solvents.
form :Crystalline Powder, Crystals and/or Chunks
pka :5.82±0.50(Predicted)
Specific Gravity :0.832
color :Light yellow or beige to brown
Sensitive :Moisture Sensitive
Hydrolytic Sensitivity :7: reacts slowly with moisture/water
BRN :1306669
CAS DataBase Reference :10416-59-8(CAS DataBase Reference)
NIST Chemistry Reference :Ethanimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester(10416-59-8)
EPA Substance Registry System :Ethanimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester (10416-59-8)
Boiling point :71-73 °C35 mm Hg(lit.)
Density :0.832 g/mL at 20 °C(lit.)
vapor pressure :10 hPa (50 °C)
refractive index :n
Flash point :53 °F
storage temp. :Store below +30°C.
solubility :Miscible with many nonpolar and polar aprotic solvents.
form :Crystalline Powder, Crystals and/or Chunks
pka :5.82±0.50(Predicted)
Specific Gravity :0.832
color :Light yellow or beige to brown
Sensitive :Moisture Sensitive
Hydrolytic Sensitivity :7: reacts slowly with moisture/water
BRN :1306669
CAS DataBase Reference :10416-59-8(CAS DataBase Reference)
NIST Chemistry Reference :Ethanimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester(10416-59-8)
EPA Substance Registry System :Ethanimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester (10416-59-8)
Safety Information
Symbol(GHS): | |||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Danger | ||||||||||||||||||||||||||||
Hazard statements: |
|
||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
N,O-Bis(trimethylsilyl)acetamide is used as a regioselective desulfation reagent as well as a preparatory agent for carbohydrate and alcohol trimethylsilyl ethers. It is also used for the derivatization of polar functional groups such as carboxylic acids, phenols, steroids, amines, alcohols, alkaloids and amides. It is employed in the formation of stable trimethylsilyl derivatives. Further, it is used in analytical chemistry for the derivatization of compounds in analysis to increase their volatility and to introduce the trimethylsilyl protecting group in organic synthesis. In addition to this, it is used in the protection of hydroxyl groups in natural products, functional groups in organic intermediates and derivatization reagent for gas chromatography-Mass spectral analysis of phenolic acids in fruits.Related product price
- Thioacetamide
$9-1270 - 2-Cyanoacetamide
$5-2420.88 - N,N-Dimethylacetamide
$5-8510
Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Shanghai Daken Advanced Materials Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Shanghai Time Chemicals CO., Ltd.