Toluene
Product identifier
- Product name: Toluene
- CBnumber: CB4233905
- CAS: 108-88-3
- EINECS Number: 203-625-9
- Synonyms: toluene,Tol
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: Toluene
- Synonyms: toluene,Tol
- CAS: 108-88-3
- EC number: 203-625-9
- MF: C7H8
- MW: 92.14
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Environmental precautions
Do not let product enter drains. Risk of explosion.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb?). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.
Handle and store under inert gas.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU). Safety glasses
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Full contact Material: Viton?
Minimum layer thickness: 0,7 mm Break through time: 480 min
Material tested:Vitoject? (KCL 890 / Aldrich Z677698, Size M)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Splash contact Material: Viton?
Minimum layer thickness: 0,7 mm Break through time: 480 min
Material tested:Vitoject? (KCL 890 / Aldrich Z677698, Size M)
Flame retardant antistatic protective clothing.
Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- Appearance liquid
- Odourbenzene-like
- Odour Threshold0,2 ppm
- pHNot applicable
- Melting point/freezing pointMelting point/range: -93 °C
- Initial boiling point and boiling range110 - 111 °C
- Flash point4,0 °C - c.c.
- Evaporation rateNo data available
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 7,1 %(V) Lower explosion limit: 1,2 %(V)
- Vapour pressure 30,88 hPa at 21,1 °C
- Vapour density 3,18
- Relative density0.865～0.870(20/20℃)(Ph.Eur.)
- Water solubility0,58 g/l at 25 °C - partly soluble
- Partition coefficient: n-octanol/waterlog Pow: 2,73 at 20 °C - Bioaccumulation is not expected.
- Autoignition temperature 535,0 °C
- Decomposition temperature No data available
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: 0,56 mPa.s at 25 °C
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
- Henry's Law Constant1.05 at 40 °C, 1.68 at 50 °C, 2.62 at 60 °C, 3.15 at 70 °C, 3.97 at 80 °C (headspace-GC, Vane et al., 2001)
Other safety information
Conductivity < 0,01 μS/cm
Surface tension 27,73 mN/m at 0,516g/l at 25 °C
Relative vapor density
3,18
Reactivity
Vapors may form explosive mixture with air. Vapors may form explosive mixture with air.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) . The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
Risk of explosion with: fuming sulfuric acid Nitric acid
silver perchlorates nitrogen dioxide
nonmetallic halides acetic acid
halogen-halogen compounds uranium hexafluoride organic nitro compounds
Violent reactions possible with: Strong acids
Strong oxidizing agents sulfur
with Heat.
Conditions to avoid
Warming. Warming.
Incompatible materials
rubber, various plastics
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicity(Tested according to Directive 92/69/EEC.)
LC50 Inhalation - Rat - male and female - 4 h - 25,7 mg/l (OECD Test Guideline 403)
LD50 Dermal - Rabbit - > 5.000 mg/kg Remarks: (ECHA)
Result: irritating - 4 h Remarks: (ECHA)
Result: slight irritation (OECD Test Guideline 405)
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476
Result: negative
Test Type: Ames test
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: Mutagenicity (Salmonella typhimurium - reverse mutation assay) Result: negative
Test Type: Chromosome aberration test Species: Rat
Cell type: Bone marrow Application Route: i.p.
Result: negative Remarks: (ECHA)
Toxicity
Remarks: (ECHA)
EC50 - Ceriodaphnia dubia (water flea) - 3,78 mg/l - 48 h (US-EPA)
Remarks: (ECHA)
Persistence and degradability
Biodegradability aerobic - Exposure time 20 d
Result: 86 % - Readily biodegradable. Remarks: (IUCLID)
Bioaccumulative potential
Bioaccumulation Leuciscus idus (Golden orfe) - 3 d
- 0,05 mg/l(Toluene)
Bioconcentration factor (BCF): 90
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
No data available
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
IncompatibilitiesIncompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Violent reaction with mixtures of nitric and sulfuric acid.
Waste DisposalConsult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.
UN number
UN proper shipping name
Transport hazard class(es)
ADR/RID: 3 IMDG: 3 IATA: 3
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
Other Information
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.