Iodomethane
Product identifier
- Product name: Iodomethane
- CBnumber: CB9326765
- CAS: 74-88-4
- EINECS Number: 200-819-5
- Synonyms: ch3i,iodomethane
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Acute toxicity - Category 3, Oral
Acute toxicity - Category 4, Dermal
Skin irritation, Category 2
Acute toxicity - Category 3, Inhalation
Specific target organ toxicity – single exposure, Category 3
Carcinogenicity, Category 2
Label elements
Pictogram(s)
- Signal wordDanger
H225 Highly Flammable liquid and vapour
H301 Toxic if swalloed
H302 Harmful if swallowed
H311 Toxic in contact with skin
H312 Harmful in contact with skin
H313 May be harmful in contact with skin
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H331 Toxic if inhaled
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335 May cause respiratory irritation
H351 Suspected of causing cancer
H370 Causes damage to organs
P201 Obtain special instructions before use.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P311 Call a POISON CENTER or doctor/physician.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P405 Store locked up.
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P203 Obtain, read and follow all safety instructions before use.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P332+P317 If skin irritation occurs: Get medical help.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316 Get emergency medical help immediately.
P319 Get medical help if you feel unwell.
P318 IF exposed or concerned, get medical advice.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: Iodomethane
- Synonyms: ch3i,iodomethane
- CAS: 74-88-4
- EC number: 200-819-5
- MF: CH3I
- MW: 141.94
Description of first aid measures
If inhaledFresh air, rest. Refer immediately for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Do NOT induce vomiting. Give a slurry of activated charcoal in water to drink. Refer immediately for medical attention.
Most important symptoms and effects, both acute and delayed
Inhalation of vapor causes lung congestion and pulmonary edema. Higher concentrations causes rapid narcosis and death. Contact with liquid irritates eyes and burns skin. (USCG, 1999)
Indication of any immediate medical attention and special treatment needed
Flush eyes thoroughly with water and wash contaminated areas of body with soap and water. Treat skin burns as usual.
Extinguishing media
Self-contained breathing apparatus with a full facepiece operated in pressure-demand or other positive-pressure mode.
Specific Hazards Arising from the Chemical
Special Hazards of Combustion Products: Toxic and irritating gases are generated when exposed to fire or heat. Behavior in Fire: Containers may explode (USCG, 1999)
Advice for firefighters
In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep drums, etc., cool by spraying with water.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 1 | Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Evacuate danger area! Consult an expert! Personal protection: self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Environmental precautions
Evacuate danger area! Consult an expert! Personal protection: self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
1. ventilate area of spill or leak. 2. collect for reclamation or absorb in vermiculite, dry sand, earth, or similar material.
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Separated from strong oxidants and food and feedstuffs. Well closed. Ventilation along the floor. Store in an area without drain or sewer access.Keep containers closed and store in a dark place.
Control parameters
Occupational Exposure limit valuesTLV: 2 ppm as TWA; (skin).MAK: skin absorption (H); carcinogen category: 2
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear safety goggles or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
Information on basic physicochemical properties
- Physical stateLiquid
- ColourClear
- Odour
Pungent, ether-like odor.
- Melting point/freezing point
252°C(dec.)(lit.)
- Boiling point or initial boiling point and boiling range
41-43°C(lit.)
- Flammability
Noncombustible Liquid
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
-18°C
- Auto-ignition temperature
355°C
- Decomposition temperature
no data available
- pH5.2 (H2O, 25℃)
- Kinematic viscosity
0.606 cP at 0 deg C, 0.424 cP at 40 deg C.
- Solubilitywater: soluble14g/L at 20°C
- Partition coefficient n-octanol/water
log Kow= 1.51
- Vapour pressure24.09 psi ( 55 °C)
- Density and/or relative density2.280
- Relative vapour density2.280
- Particle characteristics
no data available
Reactivity
NIOSH considers methyl iodide to be a potential occupational carcinogen.
Decomposes above 270°C . This produces hydrogen iodide. Reacts with strong oxidants. This generates explosion hazard. Reacts with oxygen at 300°C. This generates explosion hazard.
Chemical stability
Colorless liquid that turns yellow, red or brown when exposed to light & moisture.
Possibility of hazardous reactions
Iodomethane is not flammable.The vapour is heavier than air and may accumulate in lowered spaces causing a deficiency of oxygen.Halogenated aliphatic compounds, such as METHYL IODIDE, are moderately or very reactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, alkylphosphines, nitrides, azo/diazo compounds, alkali metals (sodium), and epoxides.
Conditions to avoid
no data available
Incompatible materials
Strong oxidizers [Note: Decomposes at 518 degrees F].
Hazardous decomposition products
Iodide & hydrogen iodide may be released when methyl iodide undergoes thermal decomposition (270 deg c).
Acute toxicity
- Oral: no data available
- Inhalation: LCLO Mouse inhalation 78,693 ppm/10 min.
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Not Likely to be Carcinogenic to Humans at Doses that Do Not Alter Rat Thyroid Hormone Homeostasis
Reproductive toxicity
No information is available on the reproductive or developmental effects of methyl iodide in humans or animals.
STOT-single exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system. The effects may be delayed. Medical observation is indicated.
STOT-repeated exposure
Tumours have been detected in experimental animals but may not be relevant to humans.
Aspiration hazard
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
no data available
Bioaccumulative potential
An estimated BCF of 2.9 was calculated for methyl iodide(SRC), using a log Kow of 1.51(1,SRC) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low. While methyl iodide has been detected in various fish and shellfish, it is thought that the chemical may have been formed biogenically(4).
Mobility in soil
Using a structure estimation method based on molecular connectivity indices(1), the Koc for methyl iodide can be estimated to be 14(SRC). According to a classification scheme(2), this estimated Koc value suggests that methyl iodide should have very high mobility in soil. The soil/water distribution coefficient of methyl iodide in various soils were (soil, Kd): Greenfield sandy loam, 0.09; Linne clay loam, 0.15; Carsetas loamy sand, 0.16; and potting mix, 0.55(3).
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: UN2644 (For reference only, please check.)
IMDG: UN2644 (For reference only, please check.)
IATA: UN2644 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: METHYL IODIDE (For reference only, please check.)
IMDG: METHYL IODIDE (For reference only, please check.)
IATA: METHYL IODIDE (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
The symptoms of acute poisoning do not become manifest until hours or even days after exposure, and they are aggravated by physical effort.
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.