Glycine hydrochloride
Product identifier
- Product name: Glycine hydrochloride
- CBnumber: CB1224948
- CAS: 6000-43-7
- EINECS Number: 227-841-8
- Synonyms: Glycine Hydrochloride,Glycine Hcl
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordWarning
Substance
- Product name: Glycine hydrochloride
- Synonyms: Glycine Hydrochloride,Glycine Hcl
- CAS: 6000-43-7
- EC number: 227-841-8
- MF: C2H6ClNO2
- MW: 111.53
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Nitrogen oxides (NOx) Hydrogen chloride gas
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
Further information
No data available
NFPA 704
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Avoid formation of dust and aerosols.
Advice on protection against fire and explosion
Provide appropriate exhaust ventilation at places where dust is formed.
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentFace shield and safety glasses Use equipment for eye protection tested and
approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm Break through time: 480 min
Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)
Splash contact Material: Nitrile rubber
Minimum layer thickness: 0,11 mm Break through time: 480 min
Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This
recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Where risk assessment shows air-purifying respirators are appropriate use a full- face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Do not let product enter drains.
Information on basic physicochemical properties
- Appearancewhite powder
- OdourNo data available
- Odour ThresholdNo data available d) pH 1,2 at 100 g/l at 23,2 °C Melting point/freezing point Initial boiling point and boiling range 173,34 - 177,56 °C at 1.013,25 hPa - OECD Test Guideline 102 229,59 °C at 1.013,25 hPa - OECD Test Guideline 103 Flash point No data available Evaporation rate No data available Flammability (solid, gas) Upper/lower flammability or explosive limits The product is not flammable. - Test N.1: Test method for readily combustible solids No data available Vapour pressure 0,0000323 hPa at 20 °C - OECD Test Guideline 104 Vapour density No data available Relative density 1,45 at 20 °C - OECD Test Guideline 109 Water solubility 825,32 g/l at 20 °C - OECD Test Guideline 105 Partition coefficient: n-octanol/water log Pow: -3,25 at 20 °C - OECD Test Guideline 107 - Bioaccumulation is not expected. Autoignition does not ignite temperature Decomposition temperature 201,01 °C - Viscosity Viscosity, kinematic: No data available Viscosity, dynamic: No data available Explosive properties No data available Oxidizing properties No data available
- Melting point/freezing point173,34 - 177,56 °C at 1.013,25 hPa - OECD Test Guideline 102
- Initial boiling point and boiling range 229,59 °C at 1.013,25 hPa - OECD Test Guideline 103
- Flash pointNo data available
- Evaporation rateNo data available
- Flammability (solid, gas)The product is not flammable. - Test N.1: Test method for readily combustible solids
- Upper/lower flammability or explosive limitsNo data available
- Vapour pressure 0,0000323 hPa at 20 °C - OECD Test Guideline 104
- Vapour density No data available
- Relative density1,45 at 20 °C - OECD Test Guideline 109
- Water solubility825,32 g/l at 20 °C - OECD Test Guideline 105
- Partition coefficient: n-octanol/waterlog Pow: -3,25 at 20 °C - OECD Test Guideline 107 - Bioaccumulation is not expected.
- Autoignition temperaturedoes not ignite
- Decomposition temperature201,01 °C -
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: No data available
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
Other safety information
No data available
Reactivity
No data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
No data available
Conditions to avoid
No data available
Incompatible materials
Strong oxidizing agents
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityEscherichia coli/Salmonella typhimurium Result: negative
Toxicity
No data available
semi-static test EC50 - Daphnia magna (Water flea) - > 220 mg/l - 48 h
(OECD Test Guideline 202)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: glycine
Persistence and degradability
Biodegradability aerobic - Exposure time 14 d
Result: 76 - 82 % - Readily biodegradable. (OECD Test Guideline 301C)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: glycine
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
No data available
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.
Contaminated packaging
Dispose of as unused product.
UN number
ADR/RID: 3261 IMDG: 3261 IATA: 3261
UN proper shipping name
ADR/RID: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (glycine hydrochloride) IMDG: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (glycine hydrochloride) IATA: Corrosive solid, acidic, organic, n.o.s. (glycine hydrochloride)
Transport hazard class(es)
ADR/RID: 8 IMDG: 8 IATA: 8
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.