no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
Fresh air, rest.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth.
No toxicity (USCG, 1999)
Pancreatic beta cells are highly sensitive to oxidative stress, which might play an important role in beta cell death in diabetes. The protective effect of 6,6'-bieckol, a phlorotannin polyphenol compound purified from Ecklonia cava, against high glucose-induced glucotoxicity was investigated in rat insulinoma cells. High glucose (30 mM) treatment induced the death of rat insulinoma cells, but treatment with 10 or 50 ug/mL 6,6'-bieckol significantly inhibited the high glucose-induced glucotoxicity. Furthermore, treatment with 6,6'-bieckol dose-dependently reduced the level of thiobarbituric acid reactive substances, generation of intracellular reactive oxygen species, and the level of nitric oxide, all of which were increased by high glucose concentration. In addition, 6,6'-bieckol protected rat insulinoma cells from apoptosis under high-glucose conditions. These effects were associated with increased expression of the anti-apoptotic protein Bcl-2 and reduced expression of the pro-apoptotic protein Bax. These findings indicate that 6,6'-bieckol could be used as a potential nutraceutical agent offering protection against the glucotoxicity caused by hyperglycemia-induced oxidative stress associated with diabetes.
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
no data available
Wear self-contained breathing apparatus for firefighting if necessary.
| HEALTH | 0 | Poses no health hazard, no precautions necessary and would offer no hazard beyond that of ordinary combustible materials | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Sweep spilled substance into covered containers. Wash away remainder with plenty of water.
ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Avoid dust formation. Avoid breathing vapors, mist or gas; Environmental precautions: No special environmental precautions required; Methods and materials for containment and cleaning up: Sweep up and shovel. Keep in suitable, closed containers for disposal.
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Separated from strong oxidants. Well closed.Keep container tightly closed in a dry and well-ventilated place. Hygroscopic. Keep in a dry place.
no data available
no data available
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
Odorless
268°C(lit.)
87°C/0.1mmHg(lit.)
Combustible.
no data available
65°C(lit.)
Not flammable (USCG, 1999)
no data available
pH of 0.5 molar aqueous solution = 5.9 /alpha-glucose/
no data available
no data available
1.83E-08mmHg at 25°C
1.732 g/cm3
no data available
no data available
Reacts violently with strong oxidants.
Stable under recommended storage conditions.
Dust explosion possible if in powder or granular form, mixed with air.A weak reducing agent.
no data available
Incompatible materials: Strong oxidizing agents
When heated to decomposition it emits acrid smoke and irritating fumes.
no data available
no data available
no data available
no data available
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no data available
AEROBIC: D(+)-Glucose, present at 1000 mg/L, reached >90% of its theoretical BOD in 2 days using a non-adapted activated sludge inoculum at 1 g/L (dry matter) in a Zahn-Wellens static test(1). The biodegradation half-life of D(+)-glucose in aerobic aquifer material (not heavily polluted), including Ontario loam and sand, South Carolina sand and Holland sand, is reported to range from 0.6-1.1 days(2). Using an electrolytic respirometry method with a 100 mg/L compound concentration and an activated sludge inoculum, D(+)-glucose was easily biodegraded with a 46-56% theoretical BOD in 100-110 hours(3). Using standard and seawater dilution methods, the 5-day BOD of D(+)-glucose was determined as 74.8 and 75.2% respectively(4). D(+)-Glucose was readily biodegradable in batch tests using adapted activated sludge with a biodegradation rate of 180.0 mg COD/g-hour(5). Biodegradation of D(+)-glucose in various samples of aquifer, saturated zone, and surface soils was found to occur rapidly with somewhat slower rates in till soil samples(6); based on measured rate constants(6), the biodegradation half-life ranged from 0.25 to 19 days.
An estimated BCF of 3 was calculated in fish for D(+)-glucose(SRC), using a log Kow of -3.00(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Using a structure estimation method based on molecular connectivity indices(1), the Koc of D(+)-glucose can be estimated to be 10(SRC). According to a classification scheme(2), this estimated Koc value suggests that D(+)-glucose is expected to have very high mobility in soil.
no data available
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
ADR/RID: UN3439 (For reference only, please check.)
IMDG: UN3439 (For reference only, please check.)
IATA: UN3439 (For reference only, please check.)
ADR/RID: NITRILES, SOLID, TOXIC, N.O.S. (For reference only, please check.)
IMDG: NITRILES, SOLID, TOXIC, N.O.S. (For reference only, please check.)
IATA: NITRILES, SOLID, TOXIC, N.O.S. (For reference only, please check.)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
ADR/RID: No
IMDG: No
IATA: No
no data available
no data available
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.