Choline chloride
Product identifier
- Product name: Choline chloride
- CBnumber: CB6166667
- CAS: 67-48-1
- EINECS Number: 200-655-4
- Synonyms: choline chloride,CHOLINE CHLORIDE 60% CORN COB
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Not classified.
Label elements
Pictogram(s)
- Signal wordWarning
H303 May be harmfulif swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
none
none
none
none
Other hazards
no data available
Substance
- Product name: Choline chloride
- Synonyms: choline chloride,CHOLINE CHLORIDE 60% CORN COB
- CAS: 67-48-1
- EC number: 200-655-4
- MF: C5H14ClNO
- MW: 139.62
Description of first aid measures
If inhaledFresh air, rest.
Rinse and then wash skin with water and soap.
Rinse with plenty of water for several minutes (remove contact lenses if easily possible).
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms and effects, both acute and delayed
no data available
Indication of any immediate medical attention and special treatment needed
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Poisons A and B
Extinguishing media
To fight fires involving this chemical, you should be equipped with an air line or self-contained breathing apparatus. Extinguish with a dry chemical, carbon dioxide, foam or halon extinguisher. (NTP, 1992)
Specific Hazards Arising from the Chemical
This chemical is relatively nonflammable. (NTP, 1992)
Advice for firefighters
Use water spray, powder.
NFPA 704
| HEALTH | 0 | Poses no health hazard, no precautions necessary and would offer no hazard beyond that of ordinary combustible materials | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 1 | Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting.
Environmental precautions
Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from strong oxidants.
Control parameters
Occupational Exposure limit valuesno data available
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear safety spectacles.
Protective gloves.
Use ventilation.
no data available
Information on basic physicochemical properties
- Physical stateAdhering Crystals
- ColourWhite
- Odour
no data available
- Melting point/freezing point
Ca. 200 °C. Atm. press.:Ca. 1 013 mBar. Remarks:First signs of an exothermal reaction were denoted at 110°C, the maximum of this reaction was at 200°C.
- Boiling point or initial boiling point and boiling range
Ca. 300 °C. Atm. press.:Ca. 1 013 mBar. Remarks:First signs of an subsequent reaction were denoted at 250°C, the maximum of this reaction was at 300°C. However, the nature of the test method does not allow to differentiate between boiling and decomposition temperature.
- Flammability
Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
60°C(lit.)
- Auto-ignition temperature
330 °C. Remarks:No further details available.
- Decomposition temperature
no data available
- pH5.0-7.5 (25℃, 1M in H2O)
- Kinematic viscosity
dynamic viscosity (in mPa s) = 26.2. Temperature:20°C. Remarks:At 20°C, the behaviour of the test substance was found to be Newtonian over the measured shear range of 10 to 200 1/s.;dynamic viscosity (in mPa s) = 14.1. Temperature:40°C. Remarks:At 40°C, the behaviour of the test substance was found to be Newtonian over the measured shear range of 10 to 200 1/s.
- SolubilityH2O: 1 M, clear, colorless
- Partition coefficient n-octanol/water
Pow = 0. Temperature:25 °C. Remarks:Average of three independent determinations.;log Pow = -3.77. Temperature:25 °C. Remarks:Average of three independent determinations.
- Vapour pressure
0 Pa. Temperature:25 °C. Remarks:Modified Grain Method (MPBPWIN v1.43), calculated for pure choline chloride.;2 287.2 Pa. Temperature:25 °C. Remarks:Modified Grain Method (MPBPWIN v1.43), calculated for 75% aqueous solution of choline chloride.
- Density and/or relative density
1.1 g/cm3. Temperature:20 °C.
- Relative vapour density
no data available
- Particle characteristics
no data available
Reactivity
On combustion, forms toxic and corrosive fumes including hydrogen chloride. Reacts with strong oxidants.
Chemical stability
Keep tightly closed.
Possibility of hazardous reactions
Choline chloride is a quaternary ammonium salt. Quaternary ammonium salts often serve as catalysts in reactions. They are incompatible with many strong oxidizers and reducing agents, such as metal hydrides, alkali/active metals, and organometallics. Quaternary ammonium salts often serve as catalysts in reactions. They are incompatible with many strong oxidizers and reducing agents, such as metal hydrides, alkali/active metals, and organometallics. Unlike the ammonium ion, [NH4]+, and the primary, secondary, or tertiary ammonium cations, the quaternary ammonium cations are permanently charged, independent of the pH of their solution.
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
When heated to decomposition it emits toxic fumes of chloride, /sulfur oxides/, and /Nitrogen oxides/.
Acute toxicity
- Oral: LD0 - rat - >= 2 790 mg/kg bw. Remarks:Given on three consecutive days, hence LD0 can be calculated as intermittent total dose to 8.37 g/kg bw.
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
A nuisance-causing concentration of airborne particles can be reached quickly when dispersed.
Toxicity
- Toxicity to fish: LC50 - Leuciscus idus - > 10 000 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 500 mg/L - 48 h.
- Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - > 500 mg/L - 72 h.
- Toxicity to microorganisms: EC10 - Pseudomonas putida - 112.9 mg/L - 17 h.
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.