Chloroacetamide
Product identifier
- Product name: Chloroacetamide
- CBnumber: CB5691957
- CAS: 79-07-2
- EINECS Number: 201-174-2
- Synonyms: 2-chloroacetamide,Chloroacetamide
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Acute toxicity - Category 3, Oral
Skin sensitization, Category 1
Reproductive toxicity, Category 2
Label elements
Pictogram(s)
- Signal wordDanger
H301 Toxic if swalloed
H317 May cause an allergic skin reaction
H361 Suspected of damaging fertility or the unborn child
H402 Harmful to aquatic life
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P318 IF exposed or concerned, get medical advice.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: Chloroacetamide
- Synonyms: 2-chloroacetamide,Chloroacetamide
- CAS: 79-07-2
- EC number: 201-174-2
- MF: C2H4ClNO
- MW: 93.51
Description of first aid measures
If inhaledFresh air, rest.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
Rinse with plenty of water for several minutes (remove contact lenses if easily possible).
Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention .
Most important symptoms and effects, both acute and delayed
no data available
Indication of any immediate medical attention and special treatment needed
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Poisons A and B
Extinguishing media
In case of fire in the surroundings, use appropriate extinguishing media.
Specific Hazards Arising from the Chemical
Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.
Advice for firefighters
In case of fire in the surroundings, use appropriate extinguishing media.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Spillage Disposal. Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from strong oxidants, strong bases, strong acids and food and feedstuffs. Ventilation along the floor. Store in an area without drain or sewer access.Separated from strong oxidants, strong bases, strong acids and food and feedstuffs. Ventilation along the floor. Store in an area without drain or sewer access.
Control parameters
Occupational Exposure limit valuesMAK skin absorption (H); MAK sensitization of skin (SH)
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear safety spectacles, face shield or eye protection in combination with breathing protection if powder.
Protective gloves. Protective clothing.
Use local exhaust or breathing protection.
no data available
Information on basic physicochemical properties
- Physical stateCrystalline Powder
- ColourWhite
- Odour
Characteristic odor
- Melting point/freezing point
118.4 °C. Remarks:Standard deviation: 0.1°C.
- Boiling point or initial boiling point and boiling range
Atm. press.:1 013.25 hPa. Remarks:No boiling point at atmospheric pressure because of decomposition.
- Flammability
Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
60°C(lit.)
- Auto-ignition temperature
no data available
- Decomposition temperature
225°C
- pH3.8-4.1 (40g/l, H2O, 20℃)
- Kinematic viscosity
no data available
- Solubilitymethanol: soluble1g/10 mL
- Partition coefficient n-octanol/water
log Pow = -0.63. Temperature:24.4 °C.;Pow = 0.233. Temperature:24.4 °C.
- Vapour pressure0.05 mm Hg ( 20 °C)
- Density and/or relative density
1.584. Temperature:20 °C.
- Relative vapour density
(air = 1): 3.2
- Particle characteristics
no data available
Reactivity
Decomposes on heating. This produces toxic fumes including nitrogen oxides and chlorine. Reacts with strong oxidants, strong reducing agents, strong acids and strong bases.
Chemical stability
Two isomorphous crystalline modifications: alpha-form, "stable form", obtained by sublimation and by crystallization from nonpolar solvents; beta-form, "unstable form", obtained by quenching the melt or by crystallization from polar solvents .
Possibility of hazardous reactions
Not combustible.
Conditions to avoid
no data available
Incompatible materials
Reacts with strong oxidants, strong reducing agents, strong acids and strong bases.
Hazardous decomposition products
Decomposes on heating. This produces toxic fumes including nitrogen oxides and chlorine.
Acute toxicity
- Oral: LD50 - rat (female) - 138 mg/kg bw.
- Inhalation: no data available
- Dermal: LD50 - rat (male/female) - > 2 000 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes and skin.
STOT-repeated exposure
Repeated or prolonged contact may cause skin sensitization. Animal tests show that this substance possibly causes toxicity to human reproduction or development.
Aspiration hazard
A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered.
Toxicity
- Toxicity to fish: LC50 - Leuciscus idus melanotus - 19.8 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 14 mg/L - 48 h.
- Toxicity to algae: EC10 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - 1.67 mg/L - 48 h.
- Toxicity to microorganisms: EC50 - activated sludge, domestic - 1 174 mg/L - 3 h. Remarks:Respiration rate.
Persistence and degradability
AEROBIC: Chloroacetamide underwent greater than 90% biodegradation in 6 days using an activated sludge inoculum and the Zahn-Wellens test(1).
Bioaccumulative potential
An estimated BCF of 3 was calculated in fish for chloroacetamide(SRC), using a log Kow of 0.53(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc of chloroacetamide is estimated as 4.2(SRC), using a log Kow of -0.53(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that chloroacetamide is expected to have very high mobility in soil.
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: UN2811 (For reference only, please check.)
IMDG: UN2811 (For reference only, please check.)
IATA: UN2811 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.)
IMDG: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.)
IATA: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Do NOT take working clothes home.
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.