2-HYDROXYPROPYL ACRYLATE
Product identifier
- Product name: 2-HYDROXYPROPYL ACRYLATE
- CBnumber: CB0766917
- CAS: 999-61-1
- EINECS Number: 213-663-8
- Synonyms: 2-HYDROXYPROPYL ACRYLATE,2HPA
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Acute toxicity - Category 3, Oral
Acute toxicity - Category 3, Dermal
Skin corrosion, Sub-category 1B
Skin sensitization, Category 1
Acute toxicity - Category 3, Inhalation
Label elements
Pictogram(s)
-
Signal word
Danger
H301 Toxic if swallowed
H311 Toxic in contact with skin
H314 Causes severe skin burns and eye damage
H317 May cause an allergic skin reaction
H331 Toxic if inhaled
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P271 Use only outdoors or in a well-ventilated area.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P363 Wash contaminated clothing before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P333+P317 If skin irritation or rash occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: 2-HYDROXYPROPYL ACRYLATE
- Synonyms: 2-HYDROXYPROPYL ACRYLATE,2HPA
- CAS: 999-61-1
- EC number: 213-663-8
- MF: C6H10O3
- MW: 130.14
Description of first aid measures
If inhaledFresh air, rest. Half-upright position. Refer immediately for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower for at least 15 minutes. Refer immediately for medical attention.
Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention.
Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention.
Most important symptoms and effects, both acute and delayed
no data available
Indication of any immediate medical attention and special treatment needed
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Poisons A and B
Extinguishing media
Extinguishing methods: Alcohol foam
Specific Hazards Arising from the Chemical
Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Above 65°C explosive vapour/air mixtures may be formed.
Advice for firefighters
Use water spray, dry powder, alcohol-resistant foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
NFPA 704
| HEALTH | |||
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 1 | Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in covered containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in covered containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
ACCIDENTAL RELEASE MEASURES. Cover with dry-lime, sand, or soda ash. Place in covered containers using non-sparking tools and transport outdoors. Ventilate area and wash spill site after material pickup is complete.
Precautions for safe handling
NO open flames. Above 65°C use a closed system and ventilation. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from food and feedstuffs. Cool. Keep in the dark. Store only if stabilized. See Notes. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.Keep tightly closed.
Control parameters
Occupational Exposure limit valuesTLV: 0.5 ppm as TWA; (skin); (SEN)
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
Information on basic physicochemical properties
- Physical stateClear to light yellow liquid
- Colour
Colorless liquid
- Odour
Faint unpleasant odor
- Melting point/freezing point
Freezing point: -30 deg C
- Boiling point or initial boiling point and boiling range
77°C 5mm
- Flammability
Class IIIA Combustible Liquid: Fl.P. at or above 140°F and below 200°F.
- Lower and upper explosion limit/flammability limit
Lower 1.4 at 212 deg F (100 deg C)
- Flash point
79.9°C
- Auto-ignition temperature
no data available
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
8.2 mm2/s at 20°C
- Solubility
Miscible with water and oxygenated solvents
- Partition coefficient n-octanol/water
log Kow = 0.35
- Vapour pressure
0.17 mm Hg at 25 deg C (est)
- Density and/or relative density
1.049 g/cm3
- Relative vapour density
4.5 (Air = 1)
- Particle characteristics
no data available
Reactivity
The substance may polymerize due to heating and under the influence of light, and peroxides. Decomposes on heating. This produces toxic and corrosive fumes including acrolein. Reacts violently with strong acids, strong bases, strong oxidants and peroxides. This generates fire hazard.
The substance may polymerize due to heating and under the influence of light, and peroxides. Decomposes on heating. This produces toxic and corrosive fumes including acrolein. Reacts violently with strong acids, strong bases, strong oxidants and peroxides. This generates fire hazard.
Chemical stability
no data available
Possibility of hazardous reactions
No data.The substance may polymerize due to heating and under the influence of light, and peroxides. Decomposes on heating. This produces toxic and corrosive fumes including acrolein. Reacts violently with strong acids, strong bases, strong oxidants and peroxides. This generates fire hazard.
Conditions to avoid
no data available
Incompatible materials
Water [Note: Can become unstable at high temperatures & pressures or may react with water with some release of energy, but not violently.]
Hazardous decomposition products
When heated to decomposition it emits acrid smoke and fumes.
Acute toxicity
- Oral: LD50 Rat oral 250 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation may cause lung oedema, but only after initial corrosive effects on eyes and/or airways have become manifest. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis. See Notes.
STOT-repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. See Notes.
Aspiration hazard
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C.
Toxicity
- Toxicity to fish: LC50; Species: Pimephales promelas (Fathead minnow, juvenile age 28-34 days, weight 0.134 g, length 20.9 mm); Conditions: freshwater, flow through, hardness 45.3 mg/L CaCO3, alkalinity 47.0 mg/L CaCO3; Concentration: 3100 ug/L for 96 hr />97% purity
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna; Conditions: static; Concentration: 24 mg/L for 48 hr; Effect: immobilization
- Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata; Conditions: static; Concentration: 3.53 mg/L for 96 hr; Effect: biomass
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: Biodegradation data specific to 2-hydroxypropyl acrylate were not located; however, results from two ready biodegradation studies are available for the commercial hydroxypropyl acrylate isomer mixture which contains approximately 70-80% 2-hydroxypropyl acrylate and 20-30% 1-methyl-2-hydroxyethyl acrylate(1,2). Hydroxypropyl acrylate, present at 100 mg/L, reached 83% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1,2). Hydroypropyl acrylate, present at 3 mg/L, reached 34.9% of its theoretical BOD after 4 weeks using a domestic activated sludge inoculum in the closed bottle test for ready biodegradability(1).
Bioaccumulative potential
An estimated BCF of 3.2 was calculated in fish for 2-hydroxypropyl acrylate(SRC), using a log Kow of 0.35(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc of 2-hydroxypropyl acrylate is estimated as 4.4(SRC), using a log Kow of 0.35(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 2-hydroxypropyl acrylate is expected to have very high mobility in soil.
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: UN2927 (For reference only, please check.)
IMDG: UN2927 (For reference only, please check.)
IATA: UN2927 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: TOXIC LIQUID, CORROSIVE, ORGANIC, N.O.S. (For reference only, please check.)
IMDG: TOXIC LIQUID, CORROSIVE, ORGANIC, N.O.S. (For reference only, please check.)
IATA: TOXIC LIQUID, CORROSIVE, ORGANIC, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Do NOT take working clothes home.Skin cross-sensitization with other acrylates is possible.An added stabilizer or inhibitor can influence the toxicological properties of this substance; consult an expert.The effectiveness of phenolic inhibitors is dependent on the presence of oxygen. Store under air rather than inert atmosphere.See ICSC 1742.
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.