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Paclitaxel Injection Concentrate for Nanodispersion

Published:7 February 2020 DOI: 10.32388/3574l6

Abstract

A nanoparticle-based injectable concentrate containing the water-insoluble taxane paclitaxel, with potential antineoplastic activity. Upon reconstitution and administration, paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. Compared to paclitaxel alone, the nanodispersion-based formulation uses less toxic solvents and allows for administration of higher doses resulting in higher concentrations of paclitaxel at the tumor site, and an increased safety profile.

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Procduct Name CAS Molecular Formula Supplier Price
Paclitaxel 33069-62-4 C47H51NO14 1111 suppliers $30.00-$4200.00

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